American Airlines flights to Knoxville

Popular flights to Knoxville

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

More Destinations Together

Our partnership with Qantas takes you to the U.S. and beyond. When you fly with American or Qantas, you can earn and redeem AAdvantage® Miles, plus, enjoy the benefits of AAdvantage® status on both airlines.

American Airlines flights to Knoxville from **Flights.FromLowestPrice***

Which airport in Knoxville does American Airlines fly to?

American flies into McGhee Tyson Airport (TYS), located about 12 miles south of downtown Knoxville. The airport is a gateway to the city's business core, local universities and scenic routes into the Smoky Mountains.

Getting from McGhee Tyson Airport to downtown Knoxville 

From TYS, several transportation options are available to connect you with your hotel, meeting location or favorite spots in and around Knoxville.

  • Public transportation: Limited bus service is available to select destinations. Check local routes for the latest schedules. 
  • Taxis / rideshare: Taxi and rideshare services are available curbside at the terminal. 
  • Hotel shuttles: Many hotels offer pre-arranged shuttle service so confirm directly with your stay. 
  • Rental cars: Major rental agencies operate on-site with access from the terminal. 

Check out TYS Airport's official website for more transportation details. 

Discover Knoxville 

Best time to visit Knoxville 

Knoxville offers 4 distinct seasons, each with something unique to offer travelers, including music, sports, festivals and fall colors. 

  • Spring (March – May): Spring welcomes blooming dogwoods and the start of the festival season, making it scenic and fun-filled. 
  • Fall (September – November): Crisp air and colorful foliage attract visitors for hiking, football weekends and local events. 

Keep in mind:

  • Summer (June – August): Warm weather pairs well with riverfront concerts and downtown nightlife. It’s also peak season for travelers heading to the Smokies.
  • Winter (December – February): Light snow and quiet downtown charm make winter a good time for indoor attractions and cozy cafes.

Top things to see and do in Knoxville 

Knoxville combines Appalachian charm with downtown culture, creating a destination with something for every kind of traveler.

  • Market Square: The walkable district is filled with restaurants, live music and seasonal farmers markets.
  • Ijams Nature Center: A favorite for hiking, paddling and connecting with nature, this center is just minutes from downtown.
  • Knoxville Museum of Art: Art lovers will enjoy this museum’s regional works and free admission.
  • World's Fair Park: Known for the Sunsphere, the park hosts events throughout the year, including music festivals and cultural fairs.
  • Old City: The historic area that now buzzes with bars, galleries and late-night venues that are ideal for evening downtime.

Booking your trip to Knoxville with American Airlines

Whether you're planning meetings in the city or a weekend exploring Tennessee trails, you’ll be welcomed by Knoxville's Southern hospitality and energy. American is here to support your trip to Knoxville, so get ready to book today.

Find deals on flights to Knoxville

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.