American Airlines flights from Charleston, SC to Louisville

Recent searches for flights from Charleston, SC to Louisville

Sep 2026
From$474*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$365*
Updated: 5 hours ago
Round tripIEconomy
Nov 2026
From$365*
Updated: 5 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $394
cmp-daily-histogram-bars-legend-max-price-aria-label $1.0K
Displaying fares for September-2026
  • CHS–SDF, 09/13/26 – 09/20/26: From $810
    13

    Su

    SEP

  • CHS–SDF, 09/14/26 – 09/21/26: From $810
    14

    Mo

  • CHS–SDF, 09/15/26 – 09/22/26: From $810
    15

    Tu

  • CHS–SDF, 09/16/26 – 09/23/26: From $810
    16

    We

  • CHS–SDF, 09/17/26 – 09/24/26: From $810
    17

    Th

  • CHS–SDF, 09/18/26 – 09/25/26: From $810
    18

    Fr

  • CHS–SDF, 09/19/26 – 09/26/26: From $810
    19

    Sa

  • CHS–SDF, 09/20/26 – 09/27/26: From $672
    20

    Su

  • CHS–SDF, 09/21/26 – 09/28/26: From $1,028
    21

    Mo

  • CHS–SDF, 09/22/26 – 09/29/26: From $672
    22

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  • CHS–SDF, 09/23/26 – 09/30/26: From $672
    23

    We

  • CHS–SDF, 09/24/26 – 10/01/26: From $672
    24

    Th

  • CHS–SDF, 09/25/26 – 10/02/26: From $672
    25

    Fr

  • CHS–SDF, 09/26/26 – 10/03/26: From $672
    26

    Sa

  • CHS–SDF, 09/27/26 – 10/04/26: From $475
    27

    Su

  • CHS–SDF, 09/28/26 – 10/05/26: From $474
    28

    Mo

  • CHS–SDF, 09/29/26 – 10/06/26: From $474
    29

    Tu

  • CHS–SDF, 09/30/26 – 10/07/26: From $474
    30

    We

  • CHS–SDF, 10/01/26 – 10/08/26: From $627
    01

    Th

    OCT

  • CHS–SDF, 10/02/26 – 10/09/26: From $474
    02

    Fr

  • CHS–SDF, 10/03/26 – 10/10/26: From $474
    03

    Sa

  • CHS–SDF, 10/04/26 – 10/11/26: From $475
    04

    Su

  • CHS–SDF, 10/05/26 – 10/12/26: From $423
    05

    Mo

  • CHS–SDF, 10/06/26 – 10/13/26: From $394
    06

    Tu

  • CHS–SDF, 10/07/26 – 10/14/26: From $394
    07

    We

  • CHS–SDF, 10/08/26 – 10/15/26: From $414
    08

    Th

  • CHS–SDF, 10/09/26 – 10/16/26: From $414
    09

    Fr

  • CHS–SDF, 10/10/26 – 10/17/26: From $414
    10

    Sa

  • CHS–SDF: cmp-view-offers-disclaimer. Find Offers
    11

    Su

  • CHS–SDF: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

    • range$394-$1,028

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Charleston, SC to Louisville flights

    $
    keyboard_arrow_down

    Charleston, SC (CHS)to

    Louisville (SDF)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    Charleston, SC (CHS)to

    Louisville (SDF)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    Charleston, SC (CHS)to

    Louisville (SDF)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    Charleston, SC (CHS)to

    Louisville (SDF)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    Charleston, SC (CHS)to

    Louisville (SDF)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    Charleston, SC (CHS)to

    Louisville (SDF)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    Charleston, SC (CHS)to

    Louisville (SDF)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    Charleston, SC (CHS)to

    Louisville (SDF)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $365Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Charleston, SC to Louisville

    Looking for lower fares on your trip from Charleston, SC to Louisville? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Charleston, SC to Louisville