American Airlines flights from Columbus to Greenville

Recent searches for flights from Columbus to Greenville

Aug 2026
From$498*
Updated: 14 hours ago
Round tripIEconomy
Sep 2026
From$257*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$279*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $257
cmp-daily-histogram-bars-legend-max-price-aria-label $695
Displaying fares for August-2026
  • CMH–GSP, 08/20/26 – 08/23/26: From $695
    20

    Th

    AUG

  • CMH–GSP, 08/21/26 – 08/28/26: From $671
    21

    Fr

  • CMH–GSP, 08/22/26 – 08/29/26: From $581
    22

    Sa

  • CMH–GSP, 08/23/26 – 08/30/26: From $671
    23

    Su

  • CMH–GSP, 08/24/26 – 08/31/26: From $671
    24

    Mo

  • CMH–GSP, 08/25/26 – 09/01/26: From $581
    25

    Tu

  • CMH–GSP, 08/26/26 – 09/02/26: From $581
    26

    We

  • CMH–GSP, 08/27/26 – 09/02/26: From $498
    27

    Th

  • CMH–GSP, 08/28/26 – 09/04/26: From $552
    28

    Fr

  • CMH–GSP, 08/29/26 – 09/05/26: From $521
    29

    Sa

  • CMH–GSP, 08/30/26 – 09/06/26: From $589
    30

    Su

  • CMH–GSP, 08/31/26 – 09/07/26: From $589
    31

    Mo

  • CMH–GSP, 09/01/26 – 09/08/26: From $521
    01

    Tu

    SEP

  • CMH–GSP, 09/02/26 – 09/09/26: From $521
    02

    We

  • CMH–GSP, 09/03/26 – 09/10/26: From $370
    03

    Th

  • CMH–GSP, 09/04/26 – 09/11/26: From $322
    04

    Fr

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    05

    Sa

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    06

    Su

  • CMH–GSP, 09/07/26 – 09/14/26: From $359
    07

    Mo

  • CMH–GSP, 09/08/26 – 09/15/26: From $370
    08

    Tu

  • CMH–GSP, 09/09/26 – 09/16/26: From $345
    09

    We

  • CMH–GSP, 09/10/26 – 09/17/26: From $429
    10

    Th

  • CMH–GSP, 09/11/26 – 09/18/26: From $257
    11

    Fr

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    12

    Sa

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    13

    Su

  • CMH–GSP, 09/14/26 – 09/21/26: From $294
    14

    Mo

  • CMH–GSP, 09/15/26 – 09/22/26: From $279
    15

    Tu

  • CMH–GSP, 09/16/26 – 09/23/26: From $279
    16

    We

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    17

    Th

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    18

    Fr

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    19

    Sa

    • range$257-$695

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Columbus to Greenville flights

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    keyboard_arrow_down

    Columbus (CMH)to

    Greenville (GSP)
    11/09/26 - 11/16/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Columbus (CMH)to

    Greenville (GSP)
    11/02/26 - 11/09/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Columbus (CMH)to

    Greenville (GSP)
    09/11/26 - 09/18/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Columbus (CMH)to

    Greenville (GSP)
    09/28/26 - 10/05/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 1 hour ago

    Columbus (CMH)to

    Greenville (GSP)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 1 hour ago

    Columbus (CMH)to

    Greenville (GSP)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 1 hour ago

    Columbus (CMH)to

    Greenville (GSP)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 1 hour ago

    Columbus (CMH)to

    Greenville (GSP)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Columbus to Greenville

    Looking for lower fares on your trip from Columbus to Greenville? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Columbus to Greenville