American Airlines flights from Des Moines to Amarillo

Recent searches for flights from Des Moines to Amarillo

Sep 2026
From$309*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$309*
Updated: 8 hours ago
Round tripIEconomy
Nov 2026
From$309*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $309
cmp-daily-histogram-bars-legend-max-price-aria-label $742
Displaying fares for September-2026
  • DSM–AMA, 09/09/26 – 09/16/26: From $742
    09

    We

    SEP

  • DSM–AMA, 09/10/26 – 09/17/26: From $742
    10

    Th

  • DSM–AMA, 09/11/26 – 09/18/26: From $742
    11

    Fr

  • DSM–AMA, 09/12/26 – 09/19/26: From $742
    12

    Sa

  • DSM–AMA, 09/13/26 – 09/20/26: From $742
    13

    Su

  • DSM–AMA, 09/14/26 – 09/21/26: From $742
    14

    Mo

  • DSM–AMA, 09/15/26 – 09/22/26: From $742
    15

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  • DSM–AMA, 09/16/26 – 09/23/26: From $612
    16

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  • DSM–AMA, 09/17/26 – 09/24/26: From $612
    17

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  • DSM–AMA, 09/18/26 – 09/25/26: From $612
    18

    Fr

  • DSM–AMA, 09/19/26 – 09/26/26: From $612
    19

    Sa

  • DSM–AMA, 09/20/26 – 09/27/26: From $612
    20

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  • DSM–AMA, 09/21/26 – 09/28/26: From $612
    21

    Mo

  • DSM–AMA, 09/22/26 – 09/29/26: From $612
    22

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  • DSM–AMA, 09/23/26 – 09/30/26: From $393
    23

    We

  • DSM–AMA, 09/24/26 – 10/01/26: From $477
    24

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  • DSM–AMA, 09/25/26 – 10/02/26: From $416
    25

    Fr

  • DSM–AMA, 09/26/26 – 10/03/26: From $393
    26

    Sa

  • DSM–AMA, 09/27/26 – 10/04/26: From $447
    27

    Su

  • DSM–AMA, 09/28/26 – 10/05/26: From $393
    28

    Mo

  • DSM–AMA, 09/29/26 – 10/06/26: From $393
    29

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  • DSM–AMA, 09/30/26 – 10/07/26: From $309
    30

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  • DSM–AMA, 10/01/26 – 10/08/26: From $332
    01

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    OCT

  • DSM–AMA, 10/02/26 – 10/09/26: From $355
    02

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  • DSM–AMA, 10/03/26 – 10/10/26: From $309
    03

    Sa

  • DSM–AMA, 10/04/26 – 10/11/26: From $437
    04

    Su

  • DSM–AMA, 10/05/26 – 10/12/26: From $355
    05

    Mo

  • DSM–AMA, 10/06/26 – 10/13/26: From $309
    06

    Tu

  • DSM–AMA: cmp-view-offers-disclaimer. Find Offers
    07

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  • DSM–AMA: cmp-view-offers-disclaimer. Find Offers
    08

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    • range$309-$742

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Amarillo flights

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    Des Moines (DSM)to

    Amarillo (AMA)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Amarillo (AMA)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Amarillo (AMA)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Amarillo (AMA)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Amarillo (AMA)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Amarillo (AMA)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Amarillo (AMA)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Amarillo (AMA)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Des Moines to Amarillo

    Looking for lower fares on your trip from Des Moines to Amarillo? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Des Moines to Amarillo