American Airlines flights from Des Moines to Guadalajara

Recent searches for flights from Des Moines to Guadalajara

Aug 2026
From$759*
Updated: 18 hours ago
Round tripIEconomy
Sep 2026
From$643*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$643*
Updated: 5 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $688
cmp-daily-histogram-bars-legend-max-price-aria-label $1.2K
Displaying fares for August-2026
  • DSM–GDL, 08/28/26 – 09/04/26: From $759
    28

    Fr

    AUG

  • DSM–GDL, 08/29/26 – 09/05/26: From $819
    29

    Sa

  • DSM–GDL, 08/30/26 – 09/06/26: From $824
    30

    Su

  • DSM–GDL, 08/31/26 – 09/07/26: From $802
    31

    Mo

  • DSM–GDL, 09/01/26 – 09/08/26: From $759
    01

    Tu

    SEP

  • DSM–GDL, 09/02/26 – 09/09/26: From $788
    02

    We

  • DSM–GDL, 09/03/26 – 09/10/26: From $907
    03

    Th

  • DSM–GDL, 09/04/26 – 09/11/26: From $1,224
    04

    Fr

  • DSM–GDL, 09/05/26 – 09/12/26: From $819
    05

    Sa

  • DSM–GDL, 09/06/26 – 09/13/26: From $824
    06

    Su

  • DSM–GDL, 09/07/26 – 09/14/26: From $802
    07

    Mo

  • DSM–GDL, 09/08/26 – 09/15/26: From $759
    08

    Tu

  • DSM–GDL, 09/09/26 – 09/16/26: From $759
    09

    We

  • DSM–GDL, 09/10/26 – 09/17/26: From $759
    10

    Th

  • DSM–GDL, 09/11/26 – 09/18/26: From $746
    11

    Fr

  • DSM–GDL, 09/12/26 – 09/19/26: From $806
    12

    Sa

  • DSM–GDL, 09/13/26 – 09/20/26: From $811
    13

    Su

  • DSM–GDL, 09/14/26 – 09/21/26: From $789
    14

    Mo

  • DSM–GDL, 09/15/26 – 09/22/26: From $746
    15

    Tu

  • DSM–GDL, 09/16/26 – 09/23/26: From $746
    16

    We

  • DSM–GDL, 09/17/26 – 09/24/26: From $746
    17

    Th

  • DSM–GDL, 09/18/26 – 09/25/26: From $688
    18

    Fr

  • DSM–GDL, 09/19/26 – 09/26/26: From $748
    19

    Sa

  • DSM–GDL, 09/20/26 – 09/27/26: From $753
    20

    Su

  • DSM–GDL, 09/21/26 – 09/28/26: From $731
    21

    Mo

  • DSM–GDL, 09/22/26 – 09/29/26: From $688
    22

    Tu

  • DSM–GDL, 09/23/26 – 09/30/26: From $688
    23

    We

  • DSM–GDL, 09/24/26 – 10/01/26: From $777
    24

    Th

  • DSM–GDL, 09/25/26 – 10/02/26: From $701
    25

    Fr

  • DSM–GDL, 09/26/26 – 10/03/26: From $703
    26

    Sa

  • DSM–GDL, 09/27/26 – 10/04/26: From $720
    27

    Su

    • range$688-$1,224

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Guadalajara flights

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    Des Moines (DSM)to

    Guadalajara (GDL)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    Des Moines (DSM)to

    Guadalajara (GDL)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    Des Moines (DSM)to

    Guadalajara (GDL)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    Des Moines (DSM)to

    Guadalajara (GDL)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    Des Moines (DSM)to

    Guadalajara (GDL)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    Des Moines (DSM)to

    Guadalajara (GDL)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    Des Moines (DSM)to

    Guadalajara (GDL)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    Des Moines (DSM)to

    Guadalajara (GDL)
    11/12/26 - 11/19/26

    Round trip

    Economy

    from
    $643Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Des Moines to Guadalajara

    Looking for lower fares on your trip from Des Moines to Guadalajara? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Des Moines to Guadalajara