American Airlines flights from Des Moines to Mcallen

Recent searches for flights from Des Moines to Mcallen

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Jul 2026
No results available
Aug 2026
From$322*
Updated: 8 hours ago
Round tripIEconomy
Sep 2026
From$295*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $322
cmp-daily-histogram-bars-legend-max-price-aria-label $836
Displaying fares for July-2026
  • DSM–MFE: cmp-view-offers-disclaimer. Find Offers
    31

    Fr

    JUL

  • DSM–MFE, 08/01/26 – 08/08/26: From $423
    01

    Sa

  • DSM–MFE, 08/02/26 – 08/09/26: From $603
    02

    Su

  • DSM–MFE, 08/03/26 – 08/10/26: From $812
    03

    Mo

  • DSM–MFE, 08/04/26 – 08/11/26: From $380
    04

    Tu

  • DSM–MFE, 08/05/26 – 08/12/26: From $767
    05

    We

  • DSM–MFE, 08/06/26 – 08/13/26: From $831
    06

    Th

  • DSM–MFE, 08/07/26 – 08/14/26: From $831
    07

    Fr

  • DSM–MFE, 08/08/26 – 08/15/26: From $805
    08

    Sa

  • DSM–MFE, 08/09/26 – 08/16/26: From $836
    09

    Su

  • DSM–MFE, 08/10/26 – 08/17/26: From $495
    10

    Mo

  • DSM–MFE, 08/11/26 – 08/18/26: From $400
    11

    Tu

  • DSM–MFE, 08/12/26 – 08/19/26: From $486
    12

    We

  • DSM–MFE, 08/13/26 – 08/20/26: From $517
    13

    Th

  • DSM–MFE, 08/14/26 – 08/21/26: From $471
    14

    Fr

  • DSM–MFE, 08/15/26 – 08/22/26: From $380
    15

    Sa

  • DSM–MFE, 08/16/26 – 08/23/26: From $603
    16

    Su

  • DSM–MFE, 08/17/26 – 08/24/26: From $445
    17

    Mo

  • DSM–MFE, 08/18/26 – 08/25/26: From $352
    18

    Tu

  • DSM–MFE, 08/19/26 – 08/26/26: From $352
    19

    We

  • DSM–MFE, 08/20/26 – 08/27/26: From $374
    20

    Th

  • DSM–MFE, 08/21/26 – 08/28/26: From $349
    21

    Fr

  • DSM–MFE, 08/22/26 – 08/29/26: From $349
    22

    Sa

  • DSM–MFE, 08/23/26 – 08/30/26: From $398
    23

    Su

  • DSM–MFE, 08/24/26 – 08/31/26: From $347
    24

    Mo

  • DSM–MFE, 08/25/26 – 09/01/26: From $322
    25

    Tu

  • DSM–MFE, 08/26/26 – 09/02/26: From $322
    26

    We

  • DSM–MFE, 08/27/26 – 09/03/26: From $347
    27

    Th

  • DSM–MFE: cmp-view-offers-disclaimer. Find Offers
    28

    Fr

  • DSM–MFE: cmp-view-offers-disclaimer. Find Offers
    29

    Sa

  • DSM–MFE: cmp-view-offers-disclaimer. Find Offers
    30

    Su

    • range$322-$836

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Mcallen flights

    $
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    Des Moines (DSM)to

    Mcallen (MFE)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Mcallen (MFE)
    09/02/26 - 09/09/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Mcallen (MFE)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Mcallen (MFE)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Mcallen (MFE)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Mcallen (MFE)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Mcallen (MFE)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    Des Moines (DSM)to

    Mcallen (MFE)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $295Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Des Moines to Mcallen

    Looking for lower fares on your trip from Des Moines to Mcallen? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Des Moines to Mcallen