American Airlines flights from Des Moines to Memphis

Recent searches for flights from Des Moines to Memphis

Aug 2026
From$299*
Updated: 9 hours ago
Round tripIEconomy
Sep 2026
From$281*
Updated: 9 hours ago
Round tripIEconomy
Oct 2026
From$299*
Updated: 9 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $299
cmp-daily-histogram-bars-legend-max-price-aria-label $774
Displaying fares for August-2026
  • DSM–MEM: cmp-view-offers-disclaimer. Find Offers
    01

    Sa

    AUG

  • DSM–MEM, 08/02/26 – 08/09/26: From $712
    02

    Su

  • DSM–MEM, 08/03/26 – 08/10/26: From $712
    03

    Mo

  • DSM–MEM, 08/04/26 – 08/11/26: From $712
    04

    Tu

  • DSM–MEM, 08/05/26 – 08/12/26: From $712
    05

    We

  • DSM–MEM, 08/06/26 – 08/13/26: From $712
    06

    Th

  • DSM–MEM, 08/07/26 – 08/14/26: From $712
    07

    Fr

  • DSM–MEM, 08/08/26 – 08/15/26: From $593
    08

    Sa

  • DSM–MEM, 08/09/26 – 08/16/26: From $774
    09

    Su

  • DSM–MEM, 08/10/26 – 08/17/26: From $593
    10

    Mo

  • DSM–MEM, 08/11/26 – 08/18/26: From $593
    11

    Tu

  • DSM–MEM, 08/12/26 – 08/19/26: From $593
    12

    We

  • DSM–MEM, 08/13/26 – 08/20/26: From $593
    13

    Th

  • DSM–MEM, 08/14/26 – 08/21/26: From $593
    14

    Fr

  • DSM–MEM, 08/15/26 – 08/22/26: From $384
    15

    Sa

  • DSM–MEM, 08/16/26 – 08/23/26: From $557
    16

    Su

  • DSM–MEM, 08/17/26 – 08/24/26: From $384
    17

    Mo

  • DSM–MEM, 08/18/26 – 08/25/26: From $384
    18

    Tu

  • DSM–MEM, 08/19/26 – 08/26/26: From $384
    19

    We

  • DSM–MEM, 08/20/26 – 08/27/26: From $384
    20

    Th

  • DSM–MEM, 08/21/26 – 08/23/26: From $363
    21

    Fr

  • DSM–MEM, 08/22/26 – 08/29/26: From $299
    22

    Sa

  • DSM–MEM, 08/23/26 – 08/30/26: From $397
    23

    Su

  • DSM–MEM, 08/24/26 – 08/31/26: From $299
    24

    Mo

  • DSM–MEM, 08/25/26 – 09/01/26: From $299
    25

    Tu

  • DSM–MEM, 08/26/26 – 09/02/26: From $299
    26

    We

  • DSM–MEM, 08/27/26 – 09/03/26: From $299
    27

    Th

  • DSM–MEM, 08/28/26 – 09/04/26: From $354
    28

    Fr

  • DSM–MEM: cmp-view-offers-disclaimer. Find Offers
    29

    Sa

  • DSM–MEM: cmp-view-offers-disclaimer. Find Offers
    30

    Su

  • DSM–MEM: cmp-view-offers-disclaimer. Find Offers
    31

    Mo

    • range$299-$774

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Memphis flights

    $
    keyboard_arrow_down

    Des Moines (DSM)to

    Memphis (MEM)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $281Fare subject to changes
    Updated: 9 hours ago

    Des Moines (DSM)to

    Memphis (MEM)
    09/02/26 - 09/09/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 9 hours ago

    Des Moines (DSM)to

    Memphis (MEM)
    09/03/26 - 09/10/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 9 hours ago

    Des Moines (DSM)to

    Memphis (MEM)
    09/09/26 - 09/16/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 9 hours ago

    Des Moines (DSM)to

    Memphis (MEM)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 9 hours ago

    Des Moines (DSM)to

    Memphis (MEM)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 9 hours ago

    Des Moines (DSM)to

    Memphis (MEM)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 9 hours ago

    Des Moines (DSM)to

    Memphis (MEM)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Des Moines to Memphis

    Looking for lower fares on your trip from Des Moines to Memphis? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Des Moines to Memphis