American Airlines flights from Des Moines to Pensacola

Recent searches for flights from Des Moines to Pensacola

Sep 2026
From$325*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$325*
Updated: 11 hours ago
Round tripIEconomy
Nov 2026
From$325*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $325
cmp-daily-histogram-bars-legend-max-price-aria-label $788
Displaying fares for September-2026
  • DSM–PNS, 09/03/26 – 09/10/26: From $788
    03

    Th

    SEP

  • DSM–PNS, 09/04/26 – 09/11/26: From $597
    04

    Fr

  • DSM–PNS, 09/05/26 – 09/12/26: From $517
    05

    Sa

  • DSM–PNS, 09/06/26 – 09/13/26: From $597
    06

    Su

  • DSM–PNS, 09/07/26 – 09/14/26: From $597
    07

    Mo

  • DSM–PNS, 09/08/26 – 09/15/26: From $517
    08

    Tu

  • DSM–PNS, 09/09/26 – 09/16/26: From $507
    09

    We

  • DSM–PNS, 09/10/26 – 09/17/26: From $583
    10

    Th

  • DSM–PNS, 09/11/26 – 09/18/26: From $415
    11

    Fr

  • DSM–PNS, 09/12/26 – 09/19/26: From $507
    12

    Sa

  • DSM–PNS, 09/13/26 – 09/20/26: From $597
    13

    Su

  • DSM–PNS, 09/14/26 – 09/21/26: From $597
    14

    Mo

  • DSM–PNS, 09/15/26 – 09/22/26: From $507
    15

    Tu

  • DSM–PNS, 09/16/26 – 09/23/26: From $421
    16

    We

  • DSM–PNS, 09/17/26 – 09/24/26: From $411
    17

    Th

  • DSM–PNS, 09/18/26 – 09/25/26: From $521
    18

    Fr

  • DSM–PNS, 09/19/26 – 09/26/26: From $421
    19

    Sa

  • DSM–PNS, 09/20/26 – 09/27/26: From $557
    20

    Su

  • DSM–PNS, 09/21/26 – 09/28/26: From $583
    21

    Mo

  • DSM–PNS, 09/22/26 – 09/29/26: From $421
    22

    Tu

  • DSM–PNS, 09/23/26 – 09/30/26: From $421
    23

    We

  • DSM–PNS, 09/24/26 – 10/01/26: From $535
    24

    Th

  • DSM–PNS, 09/25/26 – 10/02/26: From $520
    25

    Fr

  • DSM–PNS, 09/26/26 – 10/03/26: From $325
    26

    Sa

  • DSM–PNS, 09/27/26 – 10/04/26: From $452
    27

    Su

  • DSM–PNS, 09/28/26 – 10/05/26: From $424
    28

    Mo

  • DSM–PNS, 09/29/26 – 10/06/26: From $421
    29

    Tu

  • DSM–PNS, 09/30/26 – 10/07/26: From $421
    30

    We

  • DSM–PNS: cmp-view-offers-disclaimer. Find Offers
    01

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    OCT

  • DSM–PNS: cmp-view-offers-disclaimer. Find Offers
    02

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    • range$325-$788

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Pensacola flights

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    Des Moines (DSM)to

    Pensacola (PNS)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    Pensacola (PNS)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    Pensacola (PNS)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    Pensacola (PNS)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    Pensacola (PNS)
    11/09/26 - 11/16/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    Pensacola (PNS)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    Pensacola (PNS)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    Pensacola (PNS)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $325Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Des Moines to Pensacola

    Looking for lower fares on your trip from Des Moines to Pensacola? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Des Moines to Pensacola