American Airlines flights from Des Moines to Rome

Recent searches for flights from Des Moines to Rome

Sep 2026
From$927*
Updated: 6 hours ago
Round tripIEconomy
Oct 2026
From$818*
Updated: 6 hours ago
Round tripIEconomy
Nov 2026
From$752*
Updated: 6 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $927
cmp-daily-histogram-bars-legend-max-price-aria-label $3.5K
Displaying fares for September-2026
  • DSM–FCO, 09/11/26 – 09/18/26: From $3,545
    11

    Fr

    SEP

  • DSM–FCO, 09/12/26 – 09/19/26: From $1,344
    12

    Sa

  • DSM–FCO, 09/13/26 – 09/20/26: From $1,145
    13

    Su

  • DSM–FCO, 09/14/26 – 09/21/26: From $1,145
    14

    Mo

  • DSM–FCO, 09/15/26 – 09/22/26: From $1,085
    15

    Tu

  • DSM–FCO, 09/16/26 – 09/23/26: From $1,085
    16

    We

  • DSM–FCO, 09/17/26 – 09/24/26: From $1,145
    17

    Th

  • DSM–FCO, 09/18/26 – 09/25/26: From $1,377
    18

    Fr

  • DSM–FCO, 09/19/26 – 09/26/26: From $1,264
    19

    Sa

  • DSM–FCO, 09/20/26 – 09/27/26: From $1,204
    20

    Su

  • DSM–FCO, 09/21/26 – 09/28/26: From $1,211
    21

    Mo

  • DSM–FCO, 09/22/26 – 09/29/26: From $1,073
    22

    Tu

  • DSM–FCO, 09/23/26 – 09/30/26: From $1,012
    23

    We

  • DSM–FCO, 09/24/26 – 10/01/26: From $994
    24

    Th

  • DSM–FCO, 09/25/26 – 10/02/26: From $1,069
    25

    Fr

  • DSM–FCO, 09/26/26 – 10/03/26: From $1,193
    26

    Sa

  • DSM–FCO, 09/27/26 – 10/04/26: From $1,293
    27

    Su

  • DSM–FCO, 09/28/26 – 10/05/26: From $1,068
    28

    Mo

  • DSM–FCO, 09/29/26 – 10/06/26: From $930
    29

    Tu

  • DSM–FCO, 09/30/26 – 10/07/26: From $927
    30

    We

  • DSM–FCO, 10/01/26 – 10/08/26: From $987
    01

    Th

    OCT

  • DSM–FCO, 10/02/26 – 10/09/26: From $1,298
    02

    Fr

  • DSM–FCO, 10/03/26 – 10/10/26: From $1,460
    03

    Sa

  • DSM–FCO, 10/04/26 – 10/11/26: From $1,313
    04

    Su

  • DSM–FCO, 10/05/26 – 10/12/26: From $1,209
    05

    Mo

  • DSM–FCO, 10/06/26 – 10/13/26: From $1,008
    06

    Tu

  • DSM–FCO, 10/07/26 – 10/14/26: From $1,147
    07

    We

  • DSM–FCO, 10/08/26 – 10/15/26: From $1,065
    08

    Th

  • DSM–FCO, 10/09/26 – 10/16/26: From $1,468
    09

    Fr

  • DSM–FCO, 10/10/26 – 10/17/26: From $1,337
    10

    Sa

    • range$927-$3,545

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Rome flights

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    Des Moines (DSM)to

    Rome (FCO)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $749Fare subject to changes
    Updated: 6 hours ago

    Des Moines (DSM)to

    Rome (FCO)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $750Fare subject to changes
    Updated: 6 hours ago

    Des Moines (DSM)to

    Rome (FCO)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $752Fare subject to changes
    Updated: 6 hours ago

    Des Moines (DSM)to

    Rome (FCO)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $752Fare subject to changes
    Updated: 6 hours ago

    Des Moines (DSM)to

    Rome (FCO)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $752Fare subject to changes
    Updated: 6 hours ago

    Des Moines (DSM)to

    Rome (FCO)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $756Fare subject to changes
    Updated: 6 hours ago

    Des Moines (DSM)to

    Rome (FCO)
    11/25/26 - 12/02/26

    Round trip

    Economy

    from
    $762Fare subject to changes
    Updated: 6 hours ago

    Des Moines (DSM)to

    Rome (FCO)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $765Fare subject to changes
    Updated: 6 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Des Moines to Rome

    Looking for lower fares on your trip from Des Moines to Rome? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Des Moines to Rome