American Airlines flights from Des Moines to San Jose

Recent searches for flights from Des Moines to San Jose

Sep 2026
From$406*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$369*
Updated: 1 hour ago
Round tripIEconomy
Nov 2026
From$369*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $369
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for September-2026
  • DSM–SJC, 09/09/26 – 09/16/26: From $1,060
    09

    We

    SEP

  • DSM–SJC, 09/10/26 – 09/17/26: From $1,062
    10

    Th

  • DSM–SJC, 09/11/26 – 09/18/26: From $1,062
    11

    Fr

  • DSM–SJC, 09/12/26 – 09/19/26: From $1,060
    12

    Sa

  • DSM–SJC, 09/13/26 – 09/20/26: From $1,062
    13

    Su

  • DSM–SJC, 09/14/26 – 09/21/26: From $1,062
    14

    Mo

  • DSM–SJC, 09/15/26 – 09/22/26: From $1,055
    15

    Tu

  • DSM–SJC, 09/16/26 – 09/23/26: From $842
    16

    We

  • DSM–SJC, 09/17/26 – 09/24/26: From $873
    17

    Th

  • DSM–SJC, 09/18/26 – 09/25/26: From $873
    18

    Fr

  • DSM–SJC, 09/19/26 – 09/26/26: From $842
    19

    Sa

  • DSM–SJC, 09/20/26 – 09/27/26: From $842
    20

    Su

  • DSM–SJC, 09/21/26 – 09/28/26: From $842
    21

    Mo

  • DSM–SJC, 09/22/26 – 09/29/26: From $842
    22

    Tu

  • DSM–SJC, 09/23/26 – 09/30/26: From $483
    23

    We

  • DSM–SJC, 09/24/26 – 10/01/26: From $483
    24

    Th

  • DSM–SJC, 09/25/26 – 10/02/26: From $503
    25

    Fr

  • DSM–SJC, 09/26/26 – 10/03/26: From $483
    26

    Sa

  • DSM–SJC, 09/27/26 – 10/04/26: From $632
    27

    Su

  • DSM–SJC, 09/28/26 – 10/05/26: From $483
    28

    Mo

  • DSM–SJC, 09/29/26 – 10/06/26: From $483
    29

    Tu

  • DSM–SJC, 09/30/26 – 10/07/26: From $406
    30

    We

  • DSM–SJC, 10/01/26 – 10/08/26: From $459
    01

    Th

    OCT

  • DSM–SJC, 10/02/26 – 10/09/26: From $431
    02

    Fr

  • DSM–SJC, 10/03/26 – 10/10/26: From $369
    03

    Sa

  • DSM–SJC, 10/04/26 – 10/11/26: From $591
    04

    Su

  • DSM–SJC, 10/05/26 – 10/12/26: From $389
    05

    Mo

  • DSM–SJC, 10/06/26 – 10/13/26: From $369
    06

    Tu

  • DSM–SJC: cmp-view-offers-disclaimer. Find Offers
    07

    We

  • DSM–SJC: cmp-view-offers-disclaimer. Find Offers
    08

    Th

    • range$369-$1,062

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to San Jose flights

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    Des Moines (DSM)to

    San Jose (SJC)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    San Jose (SJC)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    San Jose (SJC)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    San Jose (SJC)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    San Jose (SJC)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    San Jose (SJC)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    San Jose (SJC)
    11/02/26 - 11/09/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    Des Moines (DSM)to

    San Jose (SJC)
    11/09/26 - 11/16/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Des Moines to San Jose

    Looking for lower fares on your trip from Des Moines to San Jose? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Des Moines to San Jose