American Airlines flights from Detroit to San Antonio

Recent searches for flights from Detroit to San Antonio

Aug 2026
From$814*
Updated: 9 hours ago
Round tripIEconomy
Sep 2026
From$449*
Updated: 20 hours ago
Round tripIEconomy
Oct 2026
From$449*
Updated: 9 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $449
cmp-daily-histogram-bars-legend-max-price-aria-label $818
Displaying fares for August-2026
  • DTW–SAT, 08/28/26 – 09/04/26: From $814
    28

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    AUG

  • DTW–SAT, 08/29/26 – 09/05/26: From $814
    29

    Sa

  • DTW–SAT, 08/30/26 – 09/06/26: From $814
    30

    Su

  • DTW–SAT, 08/31/26 – 09/07/26: From $814
    31

    Mo

  • DTW–SAT, 09/01/26 – 09/08/26: From $814
    01

    Tu

    SEP

  • DTW–SAT, 09/02/26 – 09/09/26: From $814
    02

    We

  • DTW–SAT, 09/03/26 – 09/10/26: From $744
    03

    Th

  • DTW–SAT, 09/04/26 – 09/11/26: From $744
    04

    Fr

  • DTW–SAT, 09/05/26 – 09/12/26: From $744
    05

    Sa

  • DTW–SAT, 09/06/26 – 09/13/26: From $744
    06

    Su

  • DTW–SAT, 09/07/26 – 09/14/26: From $744
    07

    Mo

  • DTW–SAT, 09/08/26 – 09/15/26: From $744
    08

    Tu

  • DTW–SAT, 09/09/26 – 09/16/26: From $732
    09

    We

  • DTW–SAT, 09/10/26 – 09/17/26: From $599
    10

    Th

  • DTW–SAT, 09/11/26 – 09/18/26: From $599
    11

    Fr

  • DTW–SAT, 09/12/26 – 09/19/26: From $576
    12

    Sa

  • DTW–SAT, 09/13/26 – 09/20/26: From $818
    13

    Su

  • DTW–SAT, 09/14/26 – 09/21/26: From $743
    14

    Mo

  • DTW–SAT, 09/15/26 – 09/22/26: From $576
    15

    Tu

  • DTW–SAT, 09/16/26 – 09/23/26: From $576
    16

    We

  • DTW–SAT, 09/17/26 – 09/24/26: From $539
    17

    Th

  • DTW–SAT, 09/18/26 – 09/25/26: From $549
    18

    Fr

  • DTW–SAT, 09/19/26 – 09/26/26: From $476
    19

    Sa

  • DTW–SAT, 09/20/26 – 09/27/26: From $499
    20

    Su

  • DTW–SAT, 09/21/26 – 09/28/26: From $499
    21

    Mo

  • DTW–SAT, 09/22/26 – 09/29/26: From $476
    22

    Tu

  • DTW–SAT, 09/23/26 – 09/30/26: From $499
    23

    We

  • DTW–SAT, 09/24/26 – 10/01/26: From $499
    24

    Th

  • DTW–SAT: cmp-view-offers-disclaimer. Find Offers
    25

    Fr

  • DTW–SAT: cmp-view-offers-disclaimer. Find Offers
    26

    Sa

  • DTW–SAT, 09/27/26 – 10/04/26: From $449
    27

    Su

    • range$449-$818

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Detroit to San Antonio flights

    $
    keyboard_arrow_down

    Detroit (DTW)to

    San Antonio (SAT)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    San Antonio (SAT)
    10/12/26 - 10/19/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    San Antonio (SAT)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    San Antonio (SAT)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    San Antonio (SAT)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    San Antonio (SAT)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    San Antonio (SAT)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    Detroit (DTW)to

    San Antonio (SAT)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $449Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Detroit to San Antonio

    Looking for lower fares on your trip from Detroit to San Antonio? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Detroit to San Antonio