American Airlines flights from Jacksonville to Santiago, DR

Recent searches for flights from Jacksonville to Santiago, DR

Sep 2026
From$445*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$429*
Updated: 3 hours ago
Round tripIEconomy
Nov 2026
From$424*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $445
cmp-daily-histogram-bars-legend-max-price-aria-label $3.2K
Displaying fares for September-2026
  • JAX–STI, 09/06/26 – 09/13/26: From $3,223
    06

    Su

    SEP

  • JAX–STI, 09/07/26 – 09/14/26: From $1,021
    07

    Mo

  • JAX–STI, 09/08/26 – 09/15/26: From $924
    08

    Tu

  • JAX–STI, 09/09/26 – 09/16/26: From $924
    09

    We

  • JAX–STI, 09/10/26 – 09/17/26: From $861
    10

    Th

  • JAX–STI, 09/11/26 – 09/18/26: From $856
    11

    Fr

  • JAX–STI, 09/12/26 – 09/19/26: From $894
    12

    Sa

  • JAX–STI, 09/13/26 – 09/20/26: From $894
    13

    Su

  • JAX–STI, 09/14/26 – 09/21/26: From $898
    14

    Mo

  • JAX–STI, 09/15/26 – 09/22/26: From $904
    15

    Tu

  • JAX–STI, 09/16/26 – 09/23/26: From $809
    16

    We

  • JAX–STI, 09/17/26 – 09/24/26: From $746
    17

    Th

  • JAX–STI, 09/18/26 – 09/25/26: From $741
    18

    Fr

  • JAX–STI, 09/19/26 – 09/26/26: From $865
    19

    Sa

  • JAX–STI, 09/20/26 – 09/27/26: From $870
    20

    Su

  • JAX–STI, 09/21/26 – 09/28/26: From $897
    21

    Mo

  • JAX–STI, 09/22/26 – 09/29/26: From $648
    22

    Tu

  • JAX–STI, 09/23/26 – 09/30/26: From $629
    23

    We

  • JAX–STI, 09/24/26 – 10/01/26: From $551
    24

    Th

  • JAX–STI, 09/25/26 – 10/02/26: From $609
    25

    Fr

  • JAX–STI, 09/26/26 – 10/03/26: From $760
    26

    Sa

  • JAX–STI, 09/27/26 – 10/04/26: From $760
    27

    Su

  • JAX–STI, 09/28/26 – 10/05/26: From $569
    28

    Mo

  • JAX–STI, 09/29/26 – 10/06/26: From $445
    29

    Tu

  • JAX–STI, 09/30/26 – 10/07/26: From $528
    30

    We

  • JAX–STI, 10/01/26 – 10/08/26: From $528
    01

    Th

    OCT

  • JAX–STI, 10/02/26 – 10/09/26: From $641
    02

    Fr

  • JAX–STI, 10/03/26 – 10/10/26: From $667
    03

    Sa

  • JAX–STI, 10/04/26 – 10/11/26: From $667
    04

    Su

  • JAX–STI, 10/05/26 – 10/12/26: From $548
    05

    Mo

    • range$445-$3,223

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Jacksonville to Santiago, DR flights

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    keyboard_arrow_down

    Jacksonville (JAX)to

    Santiago, DR (STI)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Santiago, DR (STI)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Santiago, DR (STI)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Santiago, DR (STI)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Santiago, DR (STI)
    11/05/26 - 11/12/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Santiago, DR (STI)
    11/12/26 - 11/19/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Santiago, DR (STI)
    11/13/26 - 11/20/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Santiago, DR (STI)
    11/24/26 - 12/01/26

    Round trip

    Economy

    from
    $424Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Jacksonville to Santiago, DR

    Looking for lower fares on your trip from Jacksonville to Santiago, DR? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
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    American Airlines flights from Jacksonville to Santiago, DR