American Airlines flights from Knoxville to Boston

Recent searches for flights from Knoxville to Boston

Sep 2026
From$432*
Updated: 21 minutes ago
Round tripIEconomy
Oct 2026
From$345*
Updated: 21 minutes ago
Round tripIEconomy
Nov 2026
From$345*
Updated: 21 minutes ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $351
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for September-2026
  • TYS–BOS, 09/13/26 – 09/20/26: From $723
    13

    Su

    SEP

  • TYS–BOS, 09/14/26 – 09/21/26: From $723
    14

    Mo

  • TYS–BOS, 09/15/26 – 09/22/26: From $723
    15

    Tu

  • TYS–BOS, 09/16/26 – 09/23/26: From $723
    16

    We

  • TYS–BOS, 09/17/26 – 09/24/26: From $723
    17

    Th

  • TYS–BOS, 09/18/26 – 09/25/26: From $748
    18

    Fr

  • TYS–BOS, 09/19/26 – 09/26/26: From $723
    19

    Sa

  • TYS–BOS, 09/20/26 – 09/27/26: From $691
    20

    Su

  • TYS–BOS, 09/21/26 – 09/28/26: From $642
    21

    Mo

  • TYS–BOS, 09/22/26 – 09/29/26: From $642
    22

    Tu

  • TYS–BOS, 09/23/26 – 09/30/26: From $642
    23

    We

  • TYS–BOS, 09/24/26 – 10/01/26: From $642
    24

    Th

  • TYS–BOS, 09/25/26 – 10/02/26: From $717
    25

    Fr

  • TYS–BOS, 09/26/26 – 10/03/26: From $642
    26

    Sa

  • TYS–BOS, 09/27/26 – 10/04/26: From $1,117
    27

    Su

  • TYS–BOS, 09/28/26 – 10/05/26: From $432
    28

    Mo

  • TYS–BOS, 09/29/26 – 10/06/26: From $432
    29

    Tu

  • TYS–BOS, 09/30/26 – 10/07/26: From $432
    30

    We

  • TYS–BOS, 10/01/26 – 10/06/26: From $432
    01

    Th

    OCT

  • TYS–BOS, 10/02/26 – 10/09/26: From $926
    02

    Fr

  • TYS–BOS, 10/03/26 – 10/10/26: From $642
    03

    Sa

  • TYS–BOS, 10/04/26 – 10/11/26: From $924
    04

    Su

  • TYS–BOS, 10/05/26 – 10/12/26: From $522
    05

    Mo

  • TYS–BOS, 10/06/26 – 10/13/26: From $351
    06

    Tu

  • TYS–BOS, 10/07/26 – 10/14/26: From $351
    07

    We

  • TYS–BOS, 10/08/26 – 10/15/26: From $479
    08

    Th

  • TYS–BOS, 10/09/26 – 10/12/26: From $491
    09

    Fr

  • TYS–BOS, 10/10/26 – 10/17/26: From $351
    10

    Sa

  • TYS–BOS: cmp-view-offers-disclaimer. Find Offers
    11

    Su

  • TYS–BOS: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

    • range$351-$1,117

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Knoxville to Boston flights

    $
    keyboard_arrow_down

    Knoxville (TYS)to

    Boston (BOS)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 17 hours ago

    Knoxville (TYS)to

    Boston (BOS)
    11/12/26 - 11/19/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 17 hours ago

    Knoxville (TYS)to

    Boston (BOS)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 21 minutes ago

    Knoxville (TYS)to

    Boston (BOS)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 21 minutes ago

    Knoxville (TYS)to

    Boston (BOS)
    10/25/26 - 11/01/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 21 minutes ago

    Knoxville (TYS)to

    Boston (BOS)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 21 minutes ago

    Knoxville (TYS)to

    Boston (BOS)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 21 minutes ago

    Knoxville (TYS)to

    Boston (BOS)
    12/04/26 - 12/11/26

    Round trip

    Economy

    from
    $345Fare subject to changes
    Updated: 21 minutes ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Knoxville to Boston

    Looking for lower fares on your trip from Knoxville to Boston? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Knoxville to Boston