American Airlines flights from Knoxville to Fort Myers

Recent searches for flights from Knoxville to Fort Myers

Sep 2026
From$363*
Updated: 9 hours ago
Round tripIEconomy
Oct 2026
From$259*
Updated: 9 hours ago
Round tripIEconomy
Nov 2026
From$259*
Updated: 9 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $259
cmp-daily-histogram-bars-legend-max-price-aria-label $887
Displaying fares for September-2026
  • TYS–RSW, 09/11/26 – 09/18/26: From $784
    11

    Fr

    SEP

  • TYS–RSW, 09/12/26 – 09/19/26: From $521
    12

    Sa

  • TYS–RSW, 09/13/26 – 09/20/26: From $679
    13

    Su

  • TYS–RSW, 09/14/26 – 09/21/26: From $679
    14

    Mo

  • TYS–RSW, 09/15/26 – 09/22/26: From $521
    15

    Tu

  • TYS–RSW, 09/16/26 – 09/23/26: From $521
    16

    We

  • TYS–RSW, 09/17/26 – 09/24/26: From $679
    17

    Th

  • TYS–RSW, 09/18/26 – 09/25/26: From $887
    18

    Fr

  • TYS–RSW, 09/19/26 – 09/26/26: From $484
    19

    Sa

  • TYS–RSW, 09/20/26 – 09/27/26: From $707
    20

    Su

  • TYS–RSW, 09/21/26 – 09/28/26: From $617
    21

    Mo

  • TYS–RSW, 09/22/26 – 09/29/26: From $484
    22

    Tu

  • TYS–RSW, 09/23/26 – 09/30/26: From $484
    23

    We

  • TYS–RSW, 09/24/26 – 10/01/26: From $457
    24

    Th

  • TYS–RSW, 09/25/26 – 10/02/26: From $457
    25

    Fr

  • TYS–RSW, 09/26/26 – 10/03/26: From $393
    26

    Sa

  • TYS–RSW, 09/27/26 – 10/04/26: From $792
    27

    Su

  • TYS–RSW, 09/28/26 – 10/05/26: From $363
    28

    Mo

  • TYS–RSW, 09/29/26 – 10/06/26: From $457
    29

    Tu

  • TYS–RSW, 09/30/26 – 10/07/26: From $393
    30

    We

  • TYS–RSW, 10/01/26 – 10/08/26: From $563
    01

    Th

    OCT

  • TYS–RSW, 10/02/26 – 10/09/26: From $681
    02

    Fr

  • TYS–RSW, 10/03/26 – 10/10/26: From $719
    03

    Sa

  • TYS–RSW, 10/04/26 – 10/11/26: From $828
    04

    Su

  • TYS–RSW, 10/05/26 – 10/12/26: From $299
    05

    Mo

  • TYS–RSW, 10/06/26 – 10/13/26: From $259
    06

    Tu

  • TYS–RSW, 10/07/26 – 10/14/26: From $293
    07

    We

  • TYS–RSW: cmp-view-offers-disclaimer. Find Offers
    08

    Th

  • TYS–RSW: cmp-view-offers-disclaimer. Find Offers
    09

    Fr

  • TYS–RSW: cmp-view-offers-disclaimer. Find Offers
    10

    Sa

    • range$259-$887

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Knoxville to Fort Myers flights

    $
    keyboard_arrow_down

    Knoxville (TYS)to

    Fort Myers (RSW)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    Knoxville (TYS)to

    Fort Myers (RSW)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    Knoxville (TYS)to

    Fort Myers (RSW)
    11/16/26 - 11/23/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    Knoxville (TYS)to

    Fort Myers (RSW)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    Knoxville (TYS)to

    Fort Myers (RSW)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    Knoxville (TYS)to

    Fort Myers (RSW)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    Knoxville (TYS)to

    Fort Myers (RSW)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    Knoxville (TYS)to

    Fort Myers (RSW)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $259Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Knoxville to Fort Myers

    Looking for lower fares on your trip from Knoxville to Fort Myers? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Knoxville to Fort Myers