American Airlines flights from Knoxville to Portland, OR

Recent searches for flights from Knoxville to Portland, OR

Aug 2026
From$665*
Updated: 10 hours ago
Round tripIEconomy
Sep 2026
From$337*
Updated: 10 hours ago
Round tripIEconomy
Oct 2026
From$337*
Updated: 10 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $337
cmp-daily-histogram-bars-legend-max-price-aria-label $795
Displaying fares for August-2026
  • TYS–PDX, 08/21/26 – 08/28/26: From $795
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  • TYS–PDX, 08/22/26 – 08/29/26: From $795
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  • TYS–PDX, 08/23/26 – 08/30/26: From $795
    23

    Su

  • TYS–PDX, 08/24/26 – 08/31/26: From $795
    24

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  • TYS–PDX, 08/25/26 – 09/01/26: From $795
    25

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  • TYS–PDX, 08/26/26 – 09/02/26: From $795
    26

    We

  • TYS–PDX, 08/27/26 – 09/03/26: From $795
    27

    Th

  • TYS–PDX, 08/28/26 – 09/04/26: From $665
    28

    Fr

  • TYS–PDX, 08/29/26 – 09/05/26: From $665
    29

    Sa

  • TYS–PDX, 08/30/26 – 09/06/26: From $665
    30

    Su

  • TYS–PDX, 08/31/26 – 09/07/26: From $795
    31

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  • TYS–PDX, 09/01/26 – 09/08/26: From $665
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    SEP

  • TYS–PDX, 09/02/26 – 09/09/26: From $665
    02

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  • TYS–PDX, 09/03/26 – 09/13/26: From $635
    03

    Th

  • TYS–PDX, 09/04/26 – 09/11/26: From $486
    04

    Fr

  • TYS–PDX, 09/05/26 – 09/12/26: From $337
    05

    Sa

  • TYS–PDX, 09/06/26 – 09/22/26: From $337
    06

    Su

  • TYS–PDX, 09/07/26 – 09/14/26: From $538
    07

    Mo

  • TYS–PDX, 09/08/26 – 09/15/26: From $462
    08

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  • TYS–PDX, 09/09/26 – 09/16/26: From $382
    09

    We

  • TYS–PDX, 09/10/26 – 09/17/26: From $521
    10

    Th

  • TYS–PDX, 09/11/26 – 09/18/26: From $361
    11

    Fr

  • TYS–PDX, 09/12/26 – 09/19/26: From $337
    12

    Sa

  • TYS–PDX, 09/13/26 – 09/20/26: From $497
    13

    Su

  • TYS–PDX, 09/14/26 – 09/21/26: From $408
    14

    Mo

  • TYS–PDX, 09/15/26 – 09/22/26: From $337
    15

    Tu

  • TYS–PDX, 09/16/26 – 09/23/26: From $408
    16

    We

  • TYS–PDX, 09/17/26 – 09/24/26: From $521
    17

    Th

  • TYS–PDX: cmp-view-offers-disclaimer. Find Offers
    18

    Fr

  • TYS–PDX: cmp-view-offers-disclaimer. Find Offers
    19

    Sa

  • TYS–PDX, 09/20/26 – 09/27/26: From $657
    20

    Su

    • range$337-$795

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Knoxville to Portland, OR flights

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    Knoxville (TYS)to

    Portland, OR (PDX)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $337Fare subject to changes
    Updated: 10 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Knoxville to Portland, OR

    Looking for lower fares on your trip from Knoxville to Portland, OR? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Knoxville to Portland, OR