American Airlines flights from Knoxville to Portland, OR

Recent searches for flights from Knoxville to Portland, OR

Aug 2026
From$423*
Updated: 2 hours ago
Round tripIEconomy
Sep 2026
From$364*
Updated: 2 hours ago
Round tripIEconomy
Oct 2026
From$404*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $423
cmp-daily-histogram-bars-legend-max-price-aria-label $940
Displaying fares for August-2026
  • TYS–PDX, 08/01/26 – 08/08/26: From $795
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    AUG

  • TYS–PDX, 08/02/26 – 08/09/26: From $940
    02

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  • TYS–PDX, 08/03/26 – 08/10/26: From $940
    03

    Mo

  • TYS–PDX, 08/04/26 – 08/11/26: From $795
    04

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  • TYS–PDX, 08/05/26 – 08/12/26: From $795
    05

    We

  • TYS–PDX, 08/06/26 – 08/13/26: From $795
    06

    Th

  • TYS–PDX, 08/07/26 – 08/14/26: From $795
    07

    Fr

  • TYS–PDX, 08/08/26 – 08/15/26: From $665
    08

    Sa

  • TYS–PDX, 08/09/26 – 08/16/26: From $665
    09

    Su

  • TYS–PDX, 08/10/26 – 08/17/26: From $665
    10

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  • TYS–PDX, 08/11/26 – 08/18/26: From $665
    11

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  • TYS–PDX, 08/12/26 – 08/19/26: From $665
    12

    We

  • TYS–PDX, 08/13/26 – 08/20/26: From $665
    13

    Th

  • TYS–PDX, 08/14/26 – 08/21/26: From $665
    14

    Fr

  • TYS–PDX, 08/15/26 – 08/22/26: From $505
    15

    Sa

  • TYS–PDX, 08/16/26 – 08/23/26: From $557
    16

    Su

  • TYS–PDX, 08/17/26 – 08/24/26: From $505
    17

    Mo

  • TYS–PDX, 08/18/26 – 08/25/26: From $505
    18

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  • TYS–PDX, 08/19/26 – 08/26/26: From $505
    19

    We

  • TYS–PDX, 08/20/26 – 08/27/26: From $505
    20

    Th

  • TYS–PDX, 08/21/26 – 08/28/26: From $516
    21

    Fr

  • TYS–PDX, 08/22/26 – 08/29/26: From $423
    22

    Sa

  • TYS–PDX, 08/23/26 – 08/30/26: From $527
    23

    Su

  • TYS–PDX, 08/24/26 – 08/31/26: From $423
    24

    Mo

  • TYS–PDX, 08/25/26 – 09/01/26: From $423
    25

    Tu

  • TYS–PDX, 08/26/26 – 09/02/26: From $423
    26

    We

  • TYS–PDX, 08/27/26 – 09/03/26: From $455
    27

    Th

  • TYS–PDX, 08/28/26 – 09/04/26: From $445
    28

    Fr

  • TYS–PDX: cmp-view-offers-disclaimer. Find Offers
    29

    Sa

  • TYS–PDX: cmp-view-offers-disclaimer. Find Offers
    30

    Su

  • TYS–PDX, 08/31/26 – 09/07/26: From $505
    31

    Mo

    • range$423-$940

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Knoxville to Portland, OR flights

    $
    keyboard_arrow_down

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $364Fare subject to changes
    Updated: 2 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/02/26 - 09/09/26

    Round trip

    Economy

    from
    $394Fare subject to changes
    Updated: 2 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/03/26 - 09/10/26

    Round trip

    Economy

    from
    $394Fare subject to changes
    Updated: 2 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $394Fare subject to changes
    Updated: 2 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/04/26 - 09/11/26

    Round trip

    Economy

    from
    $404Fare subject to changes
    Updated: 2 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    10/23/26 - 10/30/26

    Round trip

    Economy

    from
    $404Fare subject to changes
    Updated: 2 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/11/26 - 09/18/26

    Round trip

    Economy

    from
    $404Fare subject to changes
    Updated: 2 hours ago

    Knoxville (TYS)to

    Portland, OR (PDX)
    09/06/26 - 09/13/26

    Round trip

    Economy

    from
    $415Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Knoxville to Portland, OR

    Looking for lower fares on your trip from Knoxville to Portland, OR? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Knoxville to Portland, OR