American Airlines flights from Knoxville to Portland, ME

Recent searches for flights from Knoxville to Portland, ME

Sep 2026
From$440*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$373*
Updated: 5 hours ago
Round tripIEconomy
Nov 2026
From$373*
Updated: 14 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $440
cmp-daily-histogram-bars-legend-max-price-aria-label $1.0K
Displaying fares for September-2026
  • TYS–PWM, 09/13/26 – 09/20/26: From $722
    13

    Su

    SEP

  • TYS–PWM, 09/14/26 – 09/21/26: From $722
    14

    Mo

  • TYS–PWM, 09/15/26 – 09/22/26: From $585
    15

    Tu

  • TYS–PWM, 09/16/26 – 09/23/26: From $585
    16

    We

  • TYS–PWM, 09/17/26 – 09/24/26: From $722
    17

    Th

  • TYS–PWM, 09/18/26 – 09/25/26: From $722
    18

    Fr

  • TYS–PWM, 09/19/26 – 09/26/26: From $585
    19

    Sa

  • TYS–PWM, 09/20/26 – 09/27/26: From $678
    20

    Su

  • TYS–PWM, 09/21/26 – 09/28/26: From $648
    21

    Mo

  • TYS–PWM, 09/22/26 – 09/29/26: From $582
    22

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  • TYS–PWM, 09/23/26 – 09/30/26: From $582
    23

    We

  • TYS–PWM, 09/24/26 – 10/01/26: From $678
    24

    Th

  • TYS–PWM, 09/25/26 – 10/02/26: From $648
    25

    Fr

  • TYS–PWM, 09/26/26 – 10/03/26: From $582
    26

    Sa

  • TYS–PWM, 09/27/26 – 10/04/26: From $841
    27

    Su

  • TYS–PWM, 09/28/26 – 10/05/26: From $569
    28

    Mo

  • TYS–PWM, 09/29/26 – 10/06/26: From $440
    29

    Tu

  • TYS–PWM, 09/30/26 – 10/07/26: From $440
    30

    We

  • TYS–PWM, 10/01/26 – 10/08/26: From $752
    01

    Th

    OCT

  • TYS–PWM, 10/02/26 – 10/09/26: From $945
    02

    Fr

  • TYS–PWM, 10/03/26 – 10/10/26: From $829
    03

    Sa

  • TYS–PWM, 10/04/26 – 10/11/26: From $1,041
    04

    Su

  • TYS–PWM, 10/05/26 – 10/12/26: From $690
    05

    Mo

  • TYS–PWM, 10/06/26 – 10/13/26: From $596
    06

    Tu

  • TYS–PWM, 10/07/26 – 10/14/26: From $506
    07

    We

  • TYS–PWM, 10/08/26 – 10/15/26: From $652
    08

    Th

  • TYS–PWM, 10/09/26 – 10/16/26: From $652
    09

    Fr

  • TYS–PWM, 10/10/26 – 10/17/26: From $555
    10

    Sa

  • TYS–PWM: cmp-view-offers-disclaimer. Find Offers
    11

    Su

  • TYS–PWM: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

    • range$440-$1,041

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Knoxville to Portland, ME flights

    $
    keyboard_arrow_down

    Knoxville (TYS)to

    Portland, ME (PWM)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    12/04/26 - 12/11/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    11/09/26 - 11/16/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    11/19/26 - 11/26/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    10/23/26 - 10/30/26

    Round trip

    Economy

    from
    $373Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Knoxville to Portland, ME

    Looking for lower fares on your trip from Knoxville to Portland, ME? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Knoxville to Portland, ME