American Airlines flights from Knoxville to Portland, ME

Recent searches for flights from Knoxville to Portland, ME

Aug 2026
From$351*
Updated: 10 hours ago
Round tripIEconomy
Sep 2026
From$331*
Updated: 10 hours ago
Round tripIEconomy
Oct 2026
From$363*
Updated: 10 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $331
cmp-daily-histogram-bars-legend-max-price-aria-label $960
Displaying fares for August-2026
  • TYS–PWM, 08/09/26 – 08/16/26: From $960
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    AUG

  • TYS–PWM, 08/10/26 – 08/17/26: From $702
    10

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  • TYS–PWM, 08/11/26 – 08/18/26: From $565
    11

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  • TYS–PWM, 08/12/26 – 08/19/26: From $565
    12

    We

  • TYS–PWM, 08/13/26 – 08/20/26: From $702
    13

    Th

  • TYS–PWM, 08/14/26 – 08/21/26: From $702
    14

    Fr

  • TYS–PWM, 08/15/26 – 08/22/26: From $565
    15

    Sa

  • TYS–PWM, 08/16/26 – 08/23/26: From $628
    16

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  • TYS–PWM, 08/17/26 – 08/24/26: From $628
    17

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  • TYS–PWM, 08/18/26 – 08/25/26: From $562
    18

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  • TYS–PWM, 08/19/26 – 08/26/26: From $562
    19

    We

  • TYS–PWM, 08/20/26 – 08/27/26: From $627
    20

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  • TYS–PWM, 08/21/26 – 08/28/26: From $627
    21

    Fr

  • TYS–PWM, 08/22/26 – 08/29/26: From $562
    22

    Sa

  • TYS–PWM, 08/23/26 – 08/30/26: From $457
    23

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  • TYS–PWM, 08/24/26 – 08/31/26: From $457
    24

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  • TYS–PWM, 08/25/26 – 09/01/26: From $457
    25

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  • TYS–PWM, 08/26/26 – 09/02/26: From $457
    26

    We

  • TYS–PWM, 08/27/26 – 09/03/26: From $457
    27

    Th

  • TYS–PWM, 08/28/26 – 09/04/26: From $457
    28

    Fr

  • TYS–PWM, 08/29/26 – 09/05/26: From $381
    29

    Sa

  • TYS–PWM, 08/30/26 – 09/06/26: From $351
    30

    Su

  • TYS–PWM, 08/31/26 – 09/07/26: From $533
    31

    Mo

  • TYS–PWM, 09/01/26 – 09/08/26: From $533
    01

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    SEP

  • TYS–PWM, 09/02/26 – 09/09/26: From $407
    02

    We

  • TYS–PWM, 09/03/26 – 09/10/26: From $407
    03

    Th

  • TYS–PWM, 09/04/26 – 09/11/26: From $457
    04

    Fr

  • TYS–PWM, 09/05/26 – 09/12/26: From $331
    05

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  • TYS–PWM: cmp-view-offers-disclaimer. Find Offers
    06

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  • TYS–PWM: cmp-view-offers-disclaimer. Find Offers
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  • TYS–PWM: cmp-view-offers-disclaimer. Find Offers
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    • range$331-$960

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Knoxville to Portland, ME flights

    $
    keyboard_arrow_down

    Knoxville (TYS)to

    Portland, ME (PWM)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $331Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    08/30/26 - 09/06/26

    Round trip

    Economy

    from
    $351Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    10/23/26 - 10/30/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $381Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    10/05/26 - 10/12/26

    Round trip

    Economy

    from
    $387Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    10/15/26 - 10/22/26

    Round trip

    Economy

    from
    $387Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $387Fare subject to changes
    Updated: 10 hours ago

    Knoxville (TYS)to

    Portland, ME (PWM)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $387Fare subject to changes
    Updated: 10 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Knoxville to Portland, ME

    Looking for lower fares on your trip from Knoxville to Portland, ME? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Knoxville to Portland, ME