American Airlines flights from Panama City to Cleveland

Recent searches for flights from Panama City to Cleveland

Aug 2026
From$281*
Updated: 3 hours ago
Round tripIEconomy
Sep 2026
From$263*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$263*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $272
cmp-daily-histogram-bars-legend-max-price-aria-label $681
Displaying fares for August-2026
  • ECP–CLE, 08/11/26 – 08/18/26: From $589
    11

    Tu

    AUG

  • ECP–CLE, 08/12/26 – 08/19/26: From $589
    12

    We

  • ECP–CLE, 08/13/26 – 08/20/26: From $681
    13

    Th

  • ECP–CLE, 08/14/26 – 08/21/26: From $681
    14

    Fr

  • ECP–CLE, 08/15/26 – 08/22/26: From $589
    15

    Sa

  • ECP–CLE, 08/16/26 – 08/23/26: From $681
    16

    Su

  • ECP–CLE, 08/17/26 – 08/24/26: From $573
    17

    Mo

  • ECP–CLE, 08/18/26 – 08/25/26: From $497
    18

    Tu

  • ECP–CLE, 08/19/26 – 08/26/26: From $497
    19

    We

  • ECP–CLE, 08/20/26 – 08/27/26: From $573
    20

    Th

  • ECP–CLE, 08/21/26 – 08/28/26: From $573
    21

    Fr

  • ECP–CLE, 08/22/26 – 08/29/26: From $497
    22

    Sa

  • ECP–CLE, 08/23/26 – 08/30/26: From $609
    23

    Su

  • ECP–CLE, 08/24/26 – 08/31/26: From $333
    24

    Mo

  • ECP–CLE, 08/25/26 – 09/01/26: From $303
    25

    Tu

  • ECP–CLE, 08/26/26 – 09/02/26: From $303
    26

    We

  • ECP–CLE, 08/27/26 – 09/03/26: From $546
    27

    Th

  • ECP–CLE, 08/28/26 – 09/04/26: From $512
    28

    Fr

  • ECP–CLE, 08/29/26 – 09/05/26: From $303
    29

    Sa

  • ECP–CLE, 08/30/26 – 09/06/26: From $411
    30

    Su

  • ECP–CLE, 08/31/26 – 09/07/26: From $281
    31

    Mo

  • ECP–CLE, 09/01/26 – 09/08/26: From $281
    01

    Tu

    SEP

  • ECP–CLE, 09/02/26 – 09/09/26: From $272
    02

    We

  • ECP–CLE, 09/03/26 – 09/07/26: From $281
    03

    Th

  • ECP–CLE, 09/04/26 – 09/11/26: From $334
    04

    Fr

  • ECP–CLE, 09/05/26 – 09/12/26: From $272
    05

    Sa

  • ECP–CLE, 09/06/26 – 09/13/26: From $371
    06

    Su

  • ECP–CLE, 09/07/26 – 09/14/26: From $616
    07

    Mo

  • ECP–CLE: cmp-view-offers-disclaimer. Find Offers
    08

    Tu

  • ECP–CLE: cmp-view-offers-disclaimer. Find Offers
    09

    We

  • ECP–CLE, 09/10/26 – 09/17/26: From $528
    10

    Th

    • range$272-$681

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Panama City to Cleveland flights

    $
    keyboard_arrow_down

    Panama City (ECP)to

    Cleveland (CLE)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    Panama City (ECP)to

    Cleveland (CLE)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    Panama City (ECP)to

    Cleveland (CLE)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    Panama City (ECP)to

    Cleveland (CLE)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    Panama City (ECP)to

    Cleveland (CLE)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    Panama City (ECP)to

    Cleveland (CLE)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    Panama City (ECP)to

    Cleveland (CLE)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    Panama City (ECP)to

    Cleveland (CLE)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $263Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Panama City to Cleveland

    Looking for lower fares on your trip from Panama City to Cleveland? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Panama City to Cleveland