American Airlines flights from Destin to Madison

Recent searches for flights from Destin to Madison

Aug 2026
From$496*
Updated: 5 hours ago
Round tripIEconomy
Sep 2026
From$427*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$427*
Updated: 5 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $441
cmp-daily-histogram-bars-legend-max-price-aria-label $715
Displaying fares for August-2026
  • VPS–MSN, 08/18/26 – 08/25/26: From $529
    18

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    AUG

  • VPS–MSN, 08/19/26 – 08/26/26: From $529
    19

    We

  • VPS–MSN, 08/20/26 – 08/27/26: From $659
    20

    Th

  • VPS–MSN, 08/21/26 – 08/28/26: From $659
    21

    Fr

  • VPS–MSN, 08/22/26 – 08/29/26: From $529
    22

    Sa

  • VPS–MSN, 08/23/26 – 08/30/26: From $659
    23

    Su

  • VPS–MSN, 08/24/26 – 08/31/26: From $628
    24

    Mo

  • VPS–MSN, 08/25/26 – 09/01/26: From $523
    25

    Tu

  • VPS–MSN, 08/26/26 – 09/02/26: From $523
    26

    We

  • VPS–MSN, 08/27/26 – 09/03/26: From $628
    27

    Th

  • VPS–MSN, 08/28/26 – 09/04/26: From $628
    28

    Fr

  • VPS–MSN, 08/29/26 – 09/05/26: From $523
    29

    Sa

  • VPS–MSN, 08/30/26 – 09/06/26: From $628
    30

    Su

  • VPS–MSN, 08/31/26 – 09/07/26: From $496
    31

    Mo

  • VPS–MSN, 09/01/26 – 09/08/26: From $496
    01

    Tu

    SEP

  • VPS–MSN, 09/02/26 – 09/09/26: From $606
    02

    We

  • VPS–MSN, 09/03/26 – 09/10/26: From $496
    03

    Th

  • VPS–MSN, 09/04/26 – 09/11/26: From $496
    04

    Fr

  • VPS–MSN, 09/05/26 – 09/12/26: From $451
    05

    Sa

  • VPS–MSN, 09/06/26 – 09/13/26: From $451
    06

    Su

  • VPS–MSN, 09/07/26 – 09/14/26: From $715
    07

    Mo

  • VPS–MSN, 09/08/26 – 09/15/26: From $585
    08

    Tu

  • VPS–MSN, 09/09/26 – 09/16/26: From $546
    09

    We

  • VPS–MSN, 09/10/26 – 09/17/26: From $441
    10

    Th

  • VPS–MSN, 09/11/26 – 09/18/26: From $441
    11

    Fr

  • VPS–MSN, 09/12/26 – 09/19/26: From $478
    12

    Sa

  • VPS–MSN, 09/13/26 – 09/20/26: From $629
    13

    Su

  • VPS–MSN, 09/14/26 – 09/21/26: From $585
    14

    Mo

  • VPS–MSN: cmp-view-offers-disclaimer. Find Offers
    15

    Tu

  • VPS–MSN: cmp-view-offers-disclaimer. Find Offers
    16

    We

  • VPS–MSN, 09/17/26 – 09/24/26: From $577
    17

    Th

    • range$441-$715

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Destin to Madison flights

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    Destin (VPS)to

    Madison (MSN)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    Destin (VPS)to

    Madison (MSN)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    Destin (VPS)to

    Madison (MSN)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    Destin (VPS)to

    Madison (MSN)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    Destin (VPS)to

    Madison (MSN)
    09/19/26 - 09/26/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    Destin (VPS)to

    Madison (MSN)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    Destin (VPS)to

    Madison (MSN)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    Destin (VPS)to

    Madison (MSN)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Destin to Madison

    Looking for lower fares on your trip from Destin to Madison? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Destin to Madison