American Airlines flights from Destin to Portland, ME

Recent searches for flights from Destin to Portland, ME

Aug 2026
From$383*
Updated: 8 hours ago
Round tripIEconomy
Sep 2026
From$354*
Updated: 8 hours ago
Round tripIEconomy
Oct 2026
From$383*
Updated: 8 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $383
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for August-2026
  • VPS–PWM: cmp-view-offers-disclaimer. Find Offers
    01

    Sa

    AUG

  • VPS–PWM, 08/02/26 – 08/09/26: From $1,086
    02

    Su

  • VPS–PWM, 08/03/26 – 08/10/26: From $1,016
    03

    Mo

  • VPS–PWM, 08/04/26 – 08/11/26: From $917
    04

    Tu

  • VPS–PWM, 08/05/26 – 08/12/26: From $839
    05

    We

  • VPS–PWM, 08/06/26 – 08/13/26: From $938
    06

    Th

  • VPS–PWM, 08/07/26 – 08/14/26: From $938
    07

    Fr

  • VPS–PWM, 08/08/26 – 08/15/26: From $797
    08

    Sa

  • VPS–PWM, 08/09/26 – 08/16/26: From $791
    09

    Su

  • VPS–PWM, 08/10/26 – 08/17/26: From $791
    10

    Mo

  • VPS–PWM, 08/11/26 – 08/18/26: From $791
    11

    Tu

  • VPS–PWM, 08/12/26 – 08/19/26: From $749
    12

    We

  • VPS–PWM, 08/13/26 – 08/20/26: From $791
    13

    Th

  • VPS–PWM, 08/14/26 – 08/21/26: From $791
    14

    Fr

  • VPS–PWM, 08/15/26 – 08/22/26: From $649
    15

    Sa

  • VPS–PWM, 08/16/26 – 08/23/26: From $643
    16

    Su

  • VPS–PWM, 08/17/26 – 08/24/26: From $541
    17

    Mo

  • VPS–PWM, 08/18/26 – 08/25/26: From $479
    18

    Tu

  • VPS–PWM, 08/19/26 – 08/26/26: From $479
    19

    We

  • VPS–PWM, 08/20/26 – 08/27/26: From $485
    20

    Th

  • VPS–PWM, 08/21/26 – 08/28/26: From $497
    21

    Fr

  • VPS–PWM, 08/22/26 – 08/29/26: From $445
    22

    Sa

  • VPS–PWM, 08/23/26 – 08/30/26: From $495
    23

    Su

  • VPS–PWM, 08/24/26 – 08/31/26: From $439
    24

    Mo

  • VPS–PWM, 08/25/26 – 09/01/26: From $383
    25

    Tu

  • VPS–PWM, 08/26/26 – 09/02/26: From $439
    26

    We

  • VPS–PWM, 08/27/26 – 09/03/26: From $445
    27

    Th

  • VPS–PWM, 08/28/26 – 09/04/26: From $481
    28

    Fr

  • VPS–PWM: cmp-view-offers-disclaimer. Find Offers
    29

    Sa

  • VPS–PWM: cmp-view-offers-disclaimer. Find Offers
    30

    Su

  • VPS–PWM: cmp-view-offers-disclaimer. Find Offers
    31

    Mo

    • range$383-$1,086

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Destin to Portland, ME flights

    $
    keyboard_arrow_down

    Destin (VPS)to

    Portland, ME (PWM)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $354Fare subject to changes
    Updated: 8 hours ago

    Destin (VPS)to

    Portland, ME (PWM)
    09/02/26 - 09/09/26

    Round trip

    Economy

    from
    $369Fare subject to changes
    Updated: 8 hours ago

    Destin (VPS)to

    Portland, ME (PWM)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 8 hours ago

    Destin (VPS)to

    Portland, ME (PWM)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 8 hours ago

    Destin (VPS)to

    Portland, ME (PWM)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 8 hours ago

    Destin (VPS)to

    Portland, ME (PWM)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 8 hours ago

    Destin (VPS)to

    Portland, ME (PWM)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 8 hours ago

    Destin (VPS)to

    Portland, ME (PWM)
    09/01/26 - 09/08/26

    Round trip

    Economy

    from
    $383Fare subject to changes
    Updated: 8 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Destin to Portland, ME

    Looking for lower fares on your trip from Destin to Portland, ME? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Destin to Portland, ME