American Airlines flights from Destin to Syracuse

Recent searches for flights from Destin to Syracuse

Sep 2026
From$277*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$277*
Updated: 1 hour ago
Round tripIEconomy
Nov 2026
From$277*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $277
cmp-daily-histogram-bars-legend-max-price-aria-label $3.2K
Displaying fares for September-2026
  • VPS–SYR, 09/07/26 – 09/14/26: From $3,204
    07

    Mo

    SEP

  • VPS–SYR, 09/08/26 – 09/15/26: From $861
    08

    Tu

  • VPS–SYR, 09/09/26 – 09/16/26: From $511
    09

    We

  • VPS–SYR, 09/10/26 – 09/17/26: From $623
    10

    Th

  • VPS–SYR, 09/11/26 – 09/18/26: From $574
    11

    Fr

  • VPS–SYR, 09/12/26 – 09/19/26: From $511
    12

    Sa

  • VPS–SYR, 09/13/26 – 09/20/26: From $922
    13

    Su

  • VPS–SYR, 09/14/26 – 09/21/26: From $508
    14

    Mo

  • VPS–SYR, 09/15/26 – 09/22/26: From $484
    15

    Tu

  • VPS–SYR, 09/16/26 – 09/23/26: From $484
    16

    We

  • VPS–SYR, 09/17/26 – 09/24/26: From $508
    17

    Th

  • VPS–SYR, 09/18/26 – 09/25/26: From $508
    18

    Fr

  • VPS–SYR, 09/19/26 – 09/26/26: From $484
    19

    Sa

  • VPS–SYR, 09/20/26 – 09/27/26: From $593
    20

    Su

  • VPS–SYR, 09/21/26 – 09/28/26: From $506
    21

    Mo

  • VPS–SYR, 09/22/26 – 09/29/26: From $367
    22

    Tu

  • VPS–SYR, 09/23/26 – 09/30/26: From $620
    23

    We

  • VPS–SYR, 09/24/26 – 10/01/26: From $427
    24

    Th

  • VPS–SYR, 09/25/26 – 10/02/26: From $367
    25

    Fr

  • VPS–SYR, 09/26/26 – 10/03/26: From $367
    26

    Sa

  • VPS–SYR, 09/27/26 – 10/04/26: From $683
    27

    Su

  • VPS–SYR, 09/28/26 – 10/05/26: From $386
    28

    Mo

  • VPS–SYR, 09/29/26 – 10/06/26: From $277
    29

    Tu

  • VPS–SYR, 09/30/26 – 10/07/26: From $394
    30

    We

  • VPS–SYR, 10/01/26 – 10/08/26: From $627
    01

    Th

    OCT

  • VPS–SYR, 10/02/26 – 10/09/26: From $841
    02

    Fr

  • VPS–SYR, 10/03/26 – 10/10/26: From $394
    03

    Sa

  • VPS–SYR, 10/04/26 – 10/11/26: From $803
    04

    Su

  • VPS–SYR: cmp-view-offers-disclaimer. Find Offers
    05

    Mo

  • VPS–SYR: cmp-view-offers-disclaimer. Find Offers
    06

    Tu

    • range$277-$3,204

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Destin to Syracuse flights

    $
    keyboard_arrow_down

    Destin (VPS)to

    Syracuse (SYR)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    Destin (VPS)to

    Syracuse (SYR)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    Destin (VPS)to

    Syracuse (SYR)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    Destin (VPS)to

    Syracuse (SYR)
    10/23/26 - 10/30/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    Destin (VPS)to

    Syracuse (SYR)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    Destin (VPS)to

    Syracuse (SYR)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    Destin (VPS)to

    Syracuse (SYR)
    11/26/26 - 12/03/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    Destin (VPS)to

    Syracuse (SYR)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $277Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Destin to Syracuse

    Looking for lower fares on your trip from Destin to Syracuse? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Citi / AAdvantage credit card offer.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Destin to Syracuse