Flights to Cayman Islands with American Airlines

Popular flights with American Airlines

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Flights to the Cayman Islands with American Airlines

Business Class flights to Cayman Islands 

Dallas (DFW)to

Grand Cayman (GCM)
11/17/25 - 11/21/25

Round trip

Business / First

from
$1,254Fare subject to changes
Updated: 15 hours ago

Miami (MIA)to

Grand Cayman (GCM)
08/09/25 - 08/16/25

Round trip

Business / First

from
$778Fare subject to changes
Updated: 12 hours ago

Philadelphia (PHL)to

Grand Cayman (GCM)
10/02/25 - 10/06/25

Round trip

Business / First

from
$1,360Fare subject to changes
Updated: 56 minutes ago

Charlotte (CLT)to

Grand Cayman (GCM)
10/03/25 - 10/06/25

Round trip

Business / First

from
$1,365Fare subject to changes
Updated: 17 hours ago

Chicago (ORD)to

Grand Cayman (GCM)
09/11/25 - 09/20/25

Round trip

Business / First

from
$1,022Fare subject to changes
Updated: 31 minutes ago

Boston (BOS)to

Grand Cayman (GCM)
11/03/25 - 11/10/25

Round trip

Business / First

from
$1,034Fare subject to changes
Updated: 1 hour ago

Los Angeles (LAX)to

Grand Cayman (GCM)
11/14/25 - 11/22/25

Round trip

Business / First

from
$2,661Fare subject to changes
Updated: 12 hours ago

Saint Louis (STL)to

Grand Cayman (GCM)
09/30/25 - 10/07/25

Round trip

Business / First

from
$1,028Fare subject to changes
Updated: 15 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Cayman Islands

Dallas (DFW)to

Grand Cayman (GCM)
03/07/26 - 03/13/26

Round trip

Economy

from
$590Fare subject to changes
Updated: 25 minutes ago

Miami (MIA)to

Grand Cayman (GCM)
12/15/25 - 12/19/25

Round trip

Economy

from
$325Fare subject to changes
Updated: 15 hours ago

Philadelphia (PHL)to

Grand Cayman (GCM)
12/14/25 - 12/19/25

Round trip

Economy

from
$610Fare subject to changes
Updated: 2 hours ago

Charlotte (CLT)to

Grand Cayman (GCM)
11/30/25 - 12/04/25

Round trip

Economy

from
$535Fare subject to changes
Updated: 2 hours ago

Los Angeles (LAX)to

Grand Cayman (GCM)
02/07/26 - 02/21/26

Round trip

Economy

from
$636Fare subject to changes
Updated: 8 hours ago

Boston (BOS)to

Grand Cayman (GCM)
12/02/25 - 12/12/25

Round trip

Economy

from
$345Fare subject to changes
Updated: 17 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Discover best flight deals to Cayman Islands