Flights to Panama with American Airlines

Popular flights with American Airlines

  • Charlotte (CLT)to

    Panama City (PTY)
    05/16/26 - 05/19/26
    from
    $479Fare subject to changes
    Updated: 12 hours ago
    Round trip
    Economy

    Charlotte (CLT)to

    Panama City (PTY)
    05/14/26 - 05/17/26
    from
    $488Fare subject to changes
    Updated: 13 hours ago
    Round trip
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    05/11/26 - 05/18/26
    from
    $443Fare subject to changes
    Updated: 2 minutes ago
    Round trip
    Economy

    Phoenix (PHX)to

    Panama City (PTY)
    04/15/26 - 04/29/26
    from
    $482Fare subject to changes
    Updated: 4 hours ago
    Round trip
    Economy

  • Philadelphia (PHL)to

    Panama City (PTY)
    03/24/26 - 04/08/26
    from
    $537Fare subject to changes
    Updated: 9 hours ago
    Round trip
    Economy

    Philadelphia (PHL)to

    Panama City (PTY)
    03/25/26 - 04/09/26
    from
    $582Fare subject to changes
    Updated: 8 hours ago
    Round trip
    Economy

    New York (NYC)to

    Panama City (PTY)
    05/09/26 - 05/12/26
    from
    $657Fare subject to changes
    Updated: 15 hours ago
    Round trip
    Economy

    New York (NYC)to

    Panama City (PTY)
    05/22/26 - 05/26/26
    from
    $723Fare subject to changes
    Updated: 16 hours ago
    Round trip
    Economy

  • Tampa (TPA)to

    Panama City (PTY)
    04/11/26 - 04/14/26
    from
    $708Fare subject to changes
    Updated: 17 hours ago
    Round trip
    Economy

    Baltimore (BWI)to

    Panama City (PTY)
    03/25/26 - 04/14/26
    from
    $750Fare subject to changes
    Updated: 7 hours ago
    Round trip
    Economy

    Washington, D.C. (DCA)to

    Panama City (PTY)
    03/26/26 - 04/05/26
    from
    $990Fare subject to changes
    Updated: 12 hours ago
    Round trip
    Economy

    Saint Louis (STL)to

    Panama City (PTY)
    05/19/26 - 05/26/26
    from
    $509Fare subject to changes
    Updated: 16 hours ago
    Round trip
    Economy

  • Baltimore (BWI)to

    Panama City (PTY)
    03/29/26 - 04/05/26
    from
    $1,054Fare subject to changes
    Updated: 2 hours ago
    Round trip
    Economy

    New York (JFK)to

    Panama City (PTY)
    04/10/26 - 04/18/26
    from
    $788Fare subject to changes
    Updated: 3 hours ago
    Round trip
    Economy

    Orlando (MCO)to

    Panama City (PTY)
    03/26/26 - 03/31/26
    from
    $792Fare subject to changes
    Updated: 2 hours ago
    Round trip
    Economy

    New York (JFK)to

    Panama City (PTY)
    04/10/26 - 04/17/26
    from
    $758Fare subject to changes
    Updated: 15 hours ago
    Round trip
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Flights to Panama with American Airlines

Business Class flights to Panama 

Miami (MIA)to

Panama City (PTY)
07/05/26 - 07/12/26

Round trip

Business / First

from
$2,621Fare subject to changes
Updated: 4 hours ago

Dallas (DFW)to

Panama City (PTY)
03/29/26 - 04/05/26

Round trip

Business / First

from
$1,329Fare subject to changes
Updated: 13 minutes ago

Charlotte (CLT)to

Panama City (PTY)
05/16/26 - 05/19/26

Round trip

Business / First

from
$952Fare subject to changes
Updated: 12 hours ago

Philadelphia (PHL)to

Panama City (PTY)
06/25/26 - 06/30/26

Round trip

Business / First

from
$1,680Fare subject to changes
Updated: 4 hours ago

Phoenix (PHX)to

Panama City (PTY)
05/11/26 - 05/18/26

Round trip

Business / First

from
$3,635Fare subject to changes
Updated: 2 minutes ago

New York (NYC)to

Panama City (PTY)
06/01/26 - 06/04/26

Round trip

Business / First

from
$1,222Fare subject to changes
Updated: 3 hours ago

Saint Louis (STL)to

Panama City (PTY)
05/19/26 - 05/26/26

Round trip

Business / First

from
$3,920Fare subject to changes
Updated: 16 hours ago

Chicago (ORD)to

Panama City (PTY)
07/11/26 - 07/15/26

Round trip

Business / First

from
$1,462Fare subject to changes
Updated: 6 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Panama

Miami (MIA)to

Panama City (PTY)
09/29/26 - 11/02/26

Round trip

Economy

from
$382Fare subject to changes
Updated: 4 hours ago

Dallas (DFW)to

Panama City (PTY)
11/13/26 - 11/17/26

Round trip

Economy

from
$528Fare subject to changes
Updated: 15 hours ago

Phoenix (PHX)to

Panama City (PTY)
09/11/26 - 09/15/26

Round trip

Economy

from
$443Fare subject to changes
Updated: 1 hour ago

Tampa (TPA)to

Panama City (PTY)
12/06/26 - 12/13/26

Round trip

Economy

from
$546Fare subject to changes
Updated: 3 hours ago

New York (JFK)to

Panama City (PTY)
08/06/26 - 08/10/26

Round trip

Economy

from
$621Fare subject to changes
Updated: 2 hours ago

Saint Louis (STL)to

Panama City (PTY)
07/29/26 - 08/03/26

Round trip

Economy

from
$526Fare subject to changes
Updated: 5 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Earn up to $400 back on your next American Airlines flight plus, 30,000 bonus miles. Terms apply. Opens another site in a new window that may not meet accessibility guidelines.