American Airlines flights to Santo Domingo from $260*

Popular flights to Santo Domingo on American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Santo Domingo

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Miami (MIA)to

Santo Domingo (SDQ)
09/03/25 - 09/10/25

Round trip

Economy

from
$260Fare subject to changes
Updated: 3 hours ago

Philadelphia (PHL)to

Santo Domingo (SDQ)
10/11/25 - 10/18/25

Round trip

Economy

from
$319Fare subject to changes
Updated: 4 hours ago

New York (JFK)to

Santo Domingo (SDQ)
10/25/25 - 11/01/25

Round trip

Economy

from
$361Fare subject to changes
Updated: 23 hours ago

Dallas (DFW)to

Santo Domingo (SDQ)
08/20/25 - 08/27/25

Round trip

Economy

from
$555Fare subject to changes
Updated: 4 hours ago

Chicago (ORD)to

Santo Domingo (SDQ)
10/01/25 - 10/08/25

Round trip

Economy

from
$427Fare subject to changes
Updated: 4 hours ago

Tampa (TPA)to

Santo Domingo (SDQ)
10/01/25 - 10/08/25

Round trip

Economy

from
$327Fare subject to changes
Updated: 7 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Santo Domingo from **Flights.FromLowestPrice***

Santo Domingo routes with American Airlines