American Airlines flights to Santo Domingo from $250*

Popular flights to Santo Domingo on American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Santo Domingo

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Miami (MIA)to

Santo Domingo (SDQ)
09/30/25 - 10/07/25

Round trip

Economy

from
$250Fare subject to changes
Updated: 15 hours ago

Philadelphia (PHL)to

Santo Domingo (SDQ)
09/30/25 - 10/07/25

Round trip

Economy

from
$461Fare subject to changes
Updated: 6 hours ago

Tampa (TPA)to

Santo Domingo (SDQ)
10/09/25 - 10/16/25

Round trip

Economy

from
$369Fare subject to changes
Updated: 5 hours ago

Los Angeles (LAX)to

Santo Domingo (SDQ)
10/03/25 - 10/10/25

Round trip

Economy

from
$393Fare subject to changes
Updated: 6 hours ago

Charlotte (CLT)to

Santo Domingo (SDQ)
10/01/25 - 10/08/25

Round trip

Economy

from
$445Fare subject to changes
Updated: 9 hours ago

Orlando (MCO)to

Santo Domingo (SDQ)
09/30/25 - 10/07/25

Round trip

Economy

from
$341Fare subject to changes
Updated: 15 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Santo Domingo from **Flights.FromLowestPrice***

Santo Domingo routes with American Airlines