American Airlines flights to Santo Domingo from $280*

Popular flights to Santo Domingo on American Airlines

$
keyboard_arrow_down

  • Tampa (TPA)to

    Santo Domingo (SDQ)
    07/22/25 - 07/29/25
    from
    $295Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Philadelphia (PHL)to

    Santo Domingo (SDQ)
    07/18/25 - 08/10/25
    from
    $459Fare subject to changes
    Updated: 22 hours ago
    Round trip
    I
    Economy

    Boston (BOS)to

    Santo Domingo (SDQ)
    07/22/25 - 07/29/25
    from
    $391Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Houston (IAH)to

    Santo Domingo (SDQ)
    07/02/25 - 07/09/25
    from
    $515Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

  • Orlando (MCO)to

    Santo Domingo (SDQ)
    07/02/25 - 07/09/25
    from
    $365Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Raleigh (RDU)to

    Santo Domingo (SDQ)
    06/30/25 - 07/07/25
    from
    $429Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Washington, D.C. (DCA)to

    Santo Domingo (SDQ)
    08/05/25 - 08/12/25
    from
    $465Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    New York (JFK)to

    Santo Domingo (SDQ)
    05/27/25 - 06/03/25
    from
    $360Fare subject to changes
    Updated: 10 hours ago
    Round trip
    I
    Economy

  • Austin (AUS)to

    Santo Domingo (SDQ)
    07/02/25 - 07/09/25
    from
    $473Fare subject to changes
    Updated: 2 hours ago
    Round trip
    I
    Economy

    Chicago (ORD)to

    Santo Domingo (SDQ)
    08/06/25 - 08/13/25
    from
    $407Fare subject to changes
    Updated: 5 hours ago
    Round trip
    I
    Economy

    Baltimore (BWI)to

    Santo Domingo (SDQ)
    07/22/25 - 07/29/25
    from
    $445Fare subject to changes
    Updated: 4 hours ago
    Round trip
    I
    Economy

    Phoenix (PHX)to

    Santo Domingo (SDQ)
    08/02/25 - 08/09/25
    from
    $575Fare subject to changes
    Updated: 14 hours ago
    Round trip
    I
    Economy

  • San Francisco (SFO)to

    Santo Domingo (SDQ)
    08/12/25 - 08/19/25
    from
    $615Fare subject to changes
    Updated: 2 hours ago
    Round trip
    I
    Economy

    Indianapolis (IND)to

    Santo Domingo (SDQ)
    07/01/25 - 07/08/25
    from
    $515Fare subject to changes
    Updated: 3 hours ago
    Round trip
    I
    Economy

    Cleveland (CLE)to

    Santo Domingo (SDQ)
    07/30/25 - 08/06/25
    from
    $465Fare subject to changes
    Updated: 7 hours ago
    Round trip
    I
    Economy

    Chicago (CHI)to

    Santo Domingo (SDQ)
    07/08/25 - 07/15/25
    from
    $407Fare subject to changes
    Updated: 3 hours ago
    Round trip
    I
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Santo Domingo from **Flights.FromLowestPrice***

Find deals on flights to Santo Domingo

$
keyboard_arrow_down

Miami (MIA)to

Santo Domingo (SDQ)
07/22/25 - 07/29/25

Round trip

I

Economy

from
$280Fare subject to changes
Updated: 5 hours ago

Dallas (DFW)to

Santo Domingo (SDQ)
09/03/25 - 09/10/25

Round trip

I

Economy

from
$535Fare subject to changes
Updated: 5 hours ago

Charlotte (CLT)to

Santo Domingo (SDQ)
08/05/25 - 08/12/25

Round trip

I

Economy

from
$495Fare subject to changes
Updated: 5 hours ago

Los Angeles (LAX)to

Santo Domingo (SDQ)
08/05/25 - 08/12/25

Round trip

I

Economy

from
$471Fare subject to changes
Updated: 14 hours ago

Philadelphia (PHL)to

Santo Domingo (SDQ)
07/18/25 - 08/10/25

Round trip

I

Economy

from
$459Fare subject to changes
Updated: 22 hours ago

Boston (BOS)to

Santo Domingo (SDQ)
09/16/25 - 09/23/25

Round trip

I

Economy

from
$391Fare subject to changes
Updated: 4 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Santo Domingo routes with American Airlines