
American Airlines flights to Santo Domingo from $280*
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1 Adult, Economy class
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today
today
Popular flights to Santo Domingo on American Airlines
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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Santo Domingo
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Miami (MIA)to
Santo Domingo (SDQ)
07/22/25 - 07/29/25
Round trip
I
Economy
from
$280Fare subject to changes
Updated: 5 hours ago
Dallas (DFW)to
Santo Domingo (SDQ)
09/03/25 - 09/10/25
Round trip
I
Economy
from
$535Fare subject to changes
Updated: 5 hours ago
Charlotte (CLT)to
Santo Domingo (SDQ)
08/05/25 - 08/12/25
Round trip
I
Economy
from
$495Fare subject to changes
Updated: 5 hours ago
Los Angeles (LAX)to
Santo Domingo (SDQ)
08/05/25 - 08/12/25
Round trip
I
Economy
from
$471Fare subject to changes
Updated: 14 hours ago
Philadelphia (PHL)to
Santo Domingo (SDQ)
07/18/25 - 08/10/25
Round trip
I
Economy
from
$459Fare subject to changes
Updated: 22 hours ago
Boston (BOS)to
Santo Domingo (SDQ)
09/16/25 - 09/23/25
Round trip
I
Economy
from
$391Fare subject to changes
Updated: 4 hours ago
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
Santo Domingo routes with American Airlines
- Miami - Santo Domingo
- Dallas - Santo Domingo
- Los Angeles - Santo Domingo
- Philadelphia - Santo Domingo
- Boston - Santo Domingo
- Tampa - Santo Domingo
- Orlando - Santo Domingo
- Houston - Santo Domingo
- Raleigh - Santo Domingo
- Washington, D.C. - Santo Domingo
- Charlotte - Santo Domingo
- Austin - Santo Domingo
- Baltimore - Santo Domingo
- Phoenix - Santo Domingo
- San Francisco - Santo Domingo