American Airlines flights to Santo Domingo from $264*

Popular flights to Santo Domingo on American Airlines

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  • Dallas (DFW)to

    Santo Domingo (SDQ)
    02/26/26 - 03/01/26
    from
    $584Fare subject to changes
    Updated: 13 hours ago
    Round trip
    Economy

    Orlando (MCO)to

    Santo Domingo (SDQ)
    03/12/26 - 03/21/26
    from
    $413Fare subject to changes
    Updated: 5 hours ago
    Round trip
    Economy

    Tampa (TPA)to

    Santo Domingo (SDQ)
    03/11/26 - 03/23/26
    from
    $539Fare subject to changes
    Updated: 5 hours ago
    Round trip
    Economy

    Phoenix (PHX)to

    Santo Domingo (SDQ)
    03/06/26 - 03/16/26
    from
    $659Fare subject to changes
    Updated: 7 hours ago
    Round trip
    Economy

  • Boston (BOS)to

    Santo Domingo (SDQ)
    02/14/26 - 02/23/26
    from
    $491Fare subject to changes
    Updated: 5 hours ago
    Round trip
    Economy

    Nashville (BNA)to

    Santo Domingo (SDQ)
    03/06/26 - 03/11/26
    from
    $431Fare subject to changes
    Updated: 14 hours ago
    Round trip
    Economy

    Baltimore (BWI)to

    Santo Domingo (SDQ)
    03/15/26 - 03/22/26
    from
    $538Fare subject to changes
    Updated: 6 hours ago
    Round trip
    Economy

    Washington, D.C. (DCA)to

    Santo Domingo (SDQ)
    02/02/26 - 02/12/26
    from
    $624Fare subject to changes
    Updated: 11 hours ago
    Round trip
    Economy

  • Kansas City (MCI)to

    Santo Domingo (SDQ)
    03/19/26 - 03/24/26
    from
    $543Fare subject to changes
    Updated: 8 hours ago
    Round trip
    Economy

    Los Angeles (LAX)to

    Santo Domingo (SDQ)
    02/02/26 - 02/08/26
    from
    $484Fare subject to changes
    Updated: 5 hours ago
    Round trip
    Economy

    Indianapolis (IND)to

    Santo Domingo (SDQ)
    03/15/26 - 03/23/26
    from
    $553Fare subject to changes
    Updated: 7 hours ago
    Round trip
    Economy

    Atlanta (ATL)to

    Santo Domingo (SDQ)
    02/02/26 - 02/09/26
    from
    $724Fare subject to changes
    Updated: 13 hours ago
    Round trip
    Economy

  • Detroit (DTW)to

    Santo Domingo (SDQ)
    02/28/26 - 03/08/26
    from
    $709Fare subject to changes
    Updated: 10 hours ago
    Round trip
    Economy

    Cleveland (CLE)to

    Santo Domingo (SDQ)
    03/11/26 - 03/18/26
    from
    $449Fare subject to changes
    Updated: 15 hours ago
    Round trip
    Economy

    Greensboro (GSO)to

    Santo Domingo (SDQ)
    03/13/26 - 03/21/26
    from
    $513Fare subject to changes
    Updated: 8 hours ago
    Round trip
    Economy

    Houston (IAH)to

    Santo Domingo (SDQ)
    02/06/26 - 02/11/26
    from
    $674Fare subject to changes
    Updated: 10 hours ago
    Round trip
    Economy

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on flights to Santo Domingo

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Miami (MIA)to

Santo Domingo (SDQ)
02/20/26 - 02/24/26

Round trip

Economy

from
$274Fare subject to changes
Updated: 14 hours ago

Charlotte (CLT)to

Santo Domingo (SDQ)
03/27/26 - 03/31/26

Round trip

Economy

from
$539Fare subject to changes
Updated: 14 hours ago

Austin (AUS)to

Santo Domingo (SDQ)
05/25/26 - 05/29/26

Round trip

Economy

from
$347Fare subject to changes
Updated: 10 hours ago

Chicago (ORD)to

Santo Domingo (SDQ)
07/23/26 - 07/28/26

Round trip

Economy

from
$436Fare subject to changes
Updated: 12 hours ago

Dallas (DFW)to

Santo Domingo (SDQ)
07/23/26 - 07/28/26

Round trip

Economy

from
$579Fare subject to changes
Updated: 12 hours ago

Orlando (MCO)to

Santo Domingo (SDQ)
07/23/26 - 07/28/26

Round trip

Economy

from
$349Fare subject to changes
Updated: 11 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights to Santo Domingo
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Santo Domingo routes with American Airlines