American Airlines flights from Columbus to Panama City

Recent searches for flights from Columbus to Panama City

Aug 2026
From$403*
Updated: 9 hours ago
Round tripIEconomy
Sep 2026
From$333*
Updated: 9 hours ago
Round tripIEconomy
Oct 2026
From$333*
Updated: 9 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $333
cmp-daily-histogram-bars-legend-max-price-aria-label $756
Displaying fares for August-2026
  • CMH–ECP: cmp-view-offers-disclaimer. Find Offers
    14

    Fr

    AUG

  • CMH–ECP, 08/15/26 – 08/22/26: From $469
    15

    Sa

  • CMH–ECP, 08/16/26 – 08/23/26: From $736
    16

    Su

  • CMH–ECP, 08/17/26 – 08/24/26: From $469
    17

    Mo

  • CMH–ECP, 08/18/26 – 08/25/26: From $469
    18

    Tu

  • CMH–ECP, 08/19/26 – 08/26/26: From $469
    19

    We

  • CMH–ECP, 08/20/26 – 08/27/26: From $469
    20

    Th

  • CMH–ECP, 08/21/26 – 08/28/26: From $469
    21

    Fr

  • CMH–ECP, 08/22/26 – 08/29/26: From $469
    22

    Sa

  • CMH–ECP, 08/23/26 – 08/30/26: From $469
    23

    Su

  • CMH–ECP, 08/24/26 – 08/31/26: From $469
    24

    Mo

  • CMH–ECP, 08/25/26 – 09/01/26: From $469
    25

    Tu

  • CMH–ECP, 08/26/26 – 09/02/26: From $469
    26

    We

  • CMH–ECP, 08/27/26 – 09/03/26: From $469
    27

    Th

  • CMH–ECP, 08/28/26 – 09/04/26: From $421
    28

    Fr

  • CMH–ECP, 08/29/26 – 09/05/26: From $403
    29

    Sa

  • CMH–ECP, 08/30/26 – 09/06/26: From $469
    30

    Su

  • CMH–ECP, 08/31/26 – 09/07/26: From $756
    31

    Mo

  • CMH–ECP, 09/01/26 – 09/08/26: From $403
    01

    Tu

    SEP

  • CMH–ECP, 09/02/26 – 09/09/26: From $403
    02

    We

  • CMH–ECP, 09/03/26 – 09/10/26: From $518
    03

    Th

  • CMH–ECP, 09/04/26 – 09/11/26: From $536
    04

    Fr

  • CMH–ECP, 09/05/26 – 09/12/26: From $420
    05

    Sa

  • CMH–ECP, 09/06/26 – 09/13/26: From $450
    06

    Su

  • CMH–ECP, 09/07/26 – 09/14/26: From $500
    07

    Mo

  • CMH–ECP, 09/08/26 – 09/15/26: From $333
    08

    Tu

  • CMH–ECP, 09/09/26 – 09/16/26: From $333
    09

    We

  • CMH–ECP, 09/10/26 – 09/17/26: From $587
    10

    Th

  • CMH–ECP: cmp-view-offers-disclaimer. Find Offers
    11

    Fr

  • CMH–ECP: cmp-view-offers-disclaimer. Find Offers
    12

    Sa

  • CMH–ECP: cmp-view-offers-disclaimer. Find Offers
    13

    Su

    • range$333-$756

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Columbus to Panama City flights

    $
    keyboard_arrow_down

    Columbus (CMH)to

    Panama City (ECP)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    Columbus (CMH)to

    Panama City (ECP)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    Columbus (CMH)to

    Panama City (ECP)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    Columbus (CMH)to

    Panama City (ECP)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    Columbus (CMH)to

    Panama City (ECP)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    Columbus (CMH)to

    Panama City (ECP)
    09/09/26 - 09/16/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    Columbus (CMH)to

    Panama City (ECP)
    09/28/26 - 10/05/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    Columbus (CMH)to

    Panama City (ECP)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Columbus to Panama City

    Looking for lower fares on your trip from Columbus to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Columbus to Panama City