American Airlines flights from Detroit to Panama City

Recent searches for flights from Detroit to Panama City

Aug 2026
From$319*
Updated: 5 hours ago
Round tripIEconomy
Sep 2026
From$313*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$313*
Updated: 5 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $319
cmp-daily-histogram-bars-legend-max-price-aria-label $747
Displaying fares for August-2026
  • DTW–ECP: cmp-view-offers-disclaimer. Find Offers
    06

    Th

    AUG

  • DTW–ECP, 08/07/26 – 08/14/26: From $571
    07

    Fr

  • DTW–ECP, 08/08/26 – 08/15/26: From $505
    08

    Sa

  • DTW–ECP, 08/09/26 – 08/16/26: From $612
    09

    Su

  • DTW–ECP, 08/10/26 – 08/17/26: From $571
    10

    Mo

  • DTW–ECP, 08/11/26 – 08/19/26: From $483
    11

    Tu

  • DTW–ECP, 08/12/26 – 08/19/26: From $505
    12

    We

  • DTW–ECP, 08/13/26 – 08/20/26: From $570
    13

    Th

  • DTW–ECP, 08/14/26 – 08/21/26: From $570
    14

    Fr

  • DTW–ECP, 08/15/26 – 08/22/26: From $501
    15

    Sa

  • DTW–ECP, 08/16/26 – 08/23/26: From $570
    16

    Su

  • DTW–ECP, 08/17/26 – 08/24/26: From $570
    17

    Mo

  • DTW–ECP, 08/18/26 – 08/25/26: From $415
    18

    Tu

  • DTW–ECP, 08/19/26 – 08/26/26: From $415
    19

    We

  • DTW–ECP, 08/20/26 – 08/27/26: From $424
    20

    Th

  • DTW–ECP, 08/21/26 – 08/28/26: From $441
    21

    Fr

  • DTW–ECP, 08/22/26 – 08/29/26: From $325
    22

    Sa

  • DTW–ECP, 08/23/26 – 08/30/26: From $467
    23

    Su

  • DTW–ECP, 08/24/26 – 08/31/26: From $424
    24

    Mo

  • DTW–ECP, 08/25/26 – 09/01/26: From $325
    25

    Tu

  • DTW–ECP, 08/26/26 – 09/02/26: From $325
    26

    We

  • DTW–ECP, 08/27/26 – 09/03/26: From $351
    27

    Th

  • DTW–ECP, 08/28/26 – 09/04/26: From $385
    28

    Fr

  • DTW–ECP, 08/29/26 – 09/05/26: From $319
    29

    Sa

  • DTW–ECP, 08/30/26 – 09/06/26: From $381
    30

    Su

  • DTW–ECP, 08/31/26 – 09/07/26: From $747
    31

    Mo

  • DTW–ECP, 09/01/26 – 09/08/26: From $319
    01

    Tu

    SEP

  • DTW–ECP, 09/02/26 – 09/09/26: From $319
    02

    We

  • DTW–ECP: cmp-view-offers-disclaimer. Find Offers
    03

    Th

  • DTW–ECP: cmp-view-offers-disclaimer. Find Offers
    04

    Fr

  • DTW–ECP: cmp-view-offers-disclaimer. Find Offers
    05

    Sa

    • range$319-$747

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Detroit to Panama City flights

    $
    keyboard_arrow_down

    Detroit (DTW)to

    Panama City (ECP)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    09/08/26 - 09/15/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $313Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Detroit to Panama City

    Looking for lower fares on your trip from Detroit to Panama City? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Detroit to Panama City