American Airlines flights from Detroit to Panama City

Recent searches for flights from Detroit to Panama City

Sep 2026
From$477*
Updated: 14 hours ago
Round tripIEconomy
Oct 2026
From$207*
Updated: 14 hours ago
Round tripIEconomy
Nov 2026
From$207*
Updated: 14 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $207
cmp-daily-histogram-bars-legend-max-price-aria-label $682
Displaying fares for September-2026
  • DTW–ECP, 09/16/26 – 09/23/26: From $525
    16

    We

    SEP

  • DTW–ECP, 09/17/26 – 09/24/26: From $632
    17

    Th

  • DTW–ECP, 09/18/26 – 09/25/26: From $591
    18

    Fr

  • DTW–ECP, 09/19/26 – 09/26/26: From $525
    19

    Sa

  • DTW–ECP, 09/20/26 – 09/27/26: From $591
    20

    Su

  • DTW–ECP, 09/21/26 – 09/28/26: From $591
    21

    Mo

  • DTW–ECP, 09/22/26 – 09/29/26: From $521
    22

    Tu

  • DTW–ECP, 09/23/26 – 09/30/26: From $521
    23

    We

  • DTW–ECP, 09/24/26 – 10/01/26: From $682
    24

    Th

  • DTW–ECP, 09/25/26 – 10/02/26: From $682
    25

    Fr

  • DTW–ECP, 09/26/26 – 10/03/26: From $521
    26

    Sa

  • DTW–ECP, 09/27/26 – 10/04/26: From $682
    27

    Su

  • DTW–ECP, 09/28/26 – 10/05/26: From $591
    28

    Mo

  • DTW–ECP, 09/29/26 – 10/06/26: From $477
    29

    Tu

  • DTW–ECP, 09/30/26 – 10/07/26: From $481
    30

    We

  • DTW–ECP, 10/01/26 – 10/08/26: From $680
    01

    Th

    OCT

  • DTW–ECP, 10/02/26 – 10/09/26: From $595
    02

    Fr

  • DTW–ECP, 10/03/26 – 10/10/26: From $481
    03

    Sa

  • DTW–ECP, 10/04/26 – 10/11/26: From $666
    04

    Su

  • DTW–ECP, 10/05/26 – 10/12/26: From $345
    05

    Mo

  • DTW–ECP, 10/06/26 – 10/13/26: From $207
    06

    Tu

  • DTW–ECP, 10/07/26 – 10/14/26: From $241
    07

    We

  • DTW–ECP, 10/08/26 – 10/15/26: From $543
    08

    Th

  • DTW–ECP, 10/09/26 – 10/16/26: From $464
    09

    Fr

  • DTW–ECP, 10/10/26 – 10/17/26: From $392
    10

    Sa

  • DTW–ECP, 10/11/26 – 10/18/26: From $595
    11

    Su

  • DTW–ECP, 10/12/26 – 10/19/26: From $293
    12

    Mo

  • DTW–ECP, 10/13/26 – 10/20/26: From $241
    13

    Tu

  • DTW–ECP: cmp-view-offers-disclaimer. Find Offers
    14

    We

  • DTW–ECP: cmp-view-offers-disclaimer. Find Offers
    15

    Th

    • range$207-$682

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Detroit to Panama City flights

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    Detroit (DTW)to

    Panama City (ECP)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    Detroit (DTW)to

    Panama City (ECP)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $207Fare subject to changes
    Updated: 14 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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