American Airlines flights from Des Moines to Columbus

Recent searches for flights from Des Moines to Columbus

Sep 2026
From$526*
Updated: 53 minutes ago
Round tripIEconomy
Oct 2026
From$309*
Updated: 53 minutes ago
Round tripIEconomy
Nov 2026
From$291*
Updated: 20 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $309
cmp-daily-histogram-bars-legend-max-price-aria-label $697
Displaying fares for September-2026
  • DSM–CMH, 09/18/26 – 09/25/26: From $697
    18

    Fr

    SEP

  • DSM–CMH, 09/19/26 – 09/26/26: From $555
    19

    Sa

  • DSM–CMH, 09/20/26 – 09/27/26: From $697
    20

    Su

  • DSM–CMH, 09/21/26 – 09/28/26: From $697
    21

    Mo

  • DSM–CMH, 09/22/26 – 09/29/26: From $555
    22

    Tu

  • DSM–CMH, 09/23/26 – 09/30/26: From $555
    23

    We

  • DSM–CMH, 09/24/26 – 10/01/26: From $697
    24

    Th

  • DSM–CMH, 09/25/26 – 10/02/26: From $627
    25

    Fr

  • DSM–CMH, 09/26/26 – 10/03/26: From $526
    26

    Sa

  • DSM–CMH, 09/27/26 – 10/04/26: From $627
    27

    Su

  • DSM–CMH, 09/28/26 – 10/05/26: From $627
    28

    Mo

  • DSM–CMH, 09/29/26 – 10/06/26: From $526
    29

    Tu

  • DSM–CMH, 09/30/26 – 10/07/26: From $526
    30

    We

  • DSM–CMH, 10/01/26 – 10/08/26: From $627
    01

    Th

    OCT

  • DSM–CMH, 10/02/26 – 10/09/26: From $423
    02

    Fr

  • DSM–CMH, 10/03/26 – 10/10/26: From $403
    03

    Sa

  • DSM–CMH, 10/04/26 – 10/11/26: From $607
    04

    Su

  • DSM–CMH, 10/05/26 – 10/12/26: From $607
    05

    Mo

  • DSM–CMH, 10/06/26 – 10/13/26: From $403
    06

    Tu

  • DSM–CMH, 10/07/26 – 10/14/26: From $403
    07

    We

  • DSM–CMH, 10/08/26 – 10/15/26: From $597
    08

    Th

  • DSM–CMH, 10/09/26 – 10/16/26: From $467
    09

    Fr

  • DSM–CMH, 10/10/26 – 10/17/26: From $309
    10

    Sa

  • DSM–CMH, 10/11/26 – 10/18/26: From $631
    11

    Su

  • DSM–CMH, 10/12/26 – 10/19/26: From $406
    12

    Mo

  • DSM–CMH, 10/13/26 – 10/20/26: From $309
    13

    Tu

  • DSM–CMH, 10/14/26 – 10/21/26: From $380
    14

    We

  • DSM–CMH, 10/15/26 – 10/22/26: From $482
    15

    Th

  • DSM–CMH: cmp-view-offers-disclaimer. Find Offers
    16

    Fr

  • DSM–CMH: cmp-view-offers-disclaimer. Find Offers
    17

    Sa

    • range$309-$697

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Columbus flights

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    Des Moines (DSM)to

    Columbus (CMH)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 20 hours ago

    Des Moines (DSM)to

    Columbus (CMH)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 53 minutes ago

    Des Moines (DSM)to

    Columbus (CMH)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 53 minutes ago

    Des Moines (DSM)to

    Columbus (CMH)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 53 minutes ago

    Des Moines (DSM)to

    Columbus (CMH)
    12/01/26 - 12/08/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 53 minutes ago

    Des Moines (DSM)to

    Columbus (CMH)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 53 minutes ago

    Des Moines (DSM)to

    Columbus (CMH)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 53 minutes ago

    Des Moines (DSM)to

    Columbus (CMH)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 53 minutes ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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