American Airlines flights from Greenville to Columbus

Recent searches for flights from Greenville to Columbus

Aug 2026
From$581*
Updated: 20 hours ago
Round tripIEconomy
Sep 2026
From$257*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$279*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $257
cmp-daily-histogram-bars-legend-max-price-aria-label $773
Displaying fares for August-2026
  • GSP–CMH, 08/26/26 – 09/02/26: From $581
    26

    We

    AUG

  • GSP–CMH, 08/27/26 – 09/03/26: From $671
    27

    Th

  • GSP–CMH, 08/28/26 – 09/04/26: From $671
    28

    Fr

  • GSP–CMH, 08/29/26 – 09/05/26: From $581
    29

    Sa

  • GSP–CMH, 08/30/26 – 09/06/26: From $671
    30

    Su

  • GSP–CMH, 08/31/26 – 09/07/26: From $671
    31

    Mo

  • GSP–CMH, 09/01/26 – 09/08/26: From $581
    01

    Tu

    SEP

  • GSP–CMH, 09/02/26 – 09/09/26: From $521
    02

    We

  • GSP–CMH, 09/03/26 – 09/10/26: From $589
    03

    Th

  • GSP–CMH, 09/04/26 – 09/11/26: From $487
    04

    Fr

  • GSP–CMH, 09/05/26 – 09/12/26: From $570
    05

    Sa

  • GSP–CMH, 09/06/26 – 09/13/26: From $773
    06

    Su

  • GSP–CMH, 09/07/26 – 09/14/26: From $552
    07

    Mo

  • GSP–CMH, 09/08/26 – 09/15/26: From $521
    08

    Tu

  • GSP–CMH, 09/09/26 – 09/16/26: From $345
    09

    We

  • GSP–CMH, 09/10/26 – 09/17/26: From $345
    10

    Th

  • GSP–CMH, 09/11/26 – 09/14/26: From $322
    11

    Fr

  • GSP–CMH: cmp-view-offers-disclaimer. Find Offers
    12

    Sa

  • GSP–CMH: cmp-view-offers-disclaimer. Find Offers
    13

    Su

  • GSP–CMH, 09/14/26 – 09/21/26: From $511
    14

    Mo

  • GSP–CMH, 09/15/26 – 09/22/26: From $370
    15

    Tu

  • GSP–CMH, 09/16/26 – 09/23/26: From $279
    16

    We

  • GSP–CMH, 09/17/26 – 09/24/26: From $432
    17

    Th

  • GSP–CMH, 09/18/26 – 09/25/26: From $361
    18

    Fr

  • GSP–CMH: cmp-view-offers-disclaimer. Find Offers
    19

    Sa

  • GSP–CMH: cmp-view-offers-disclaimer. Find Offers
    20

    Su

  • GSP–CMH, 09/21/26 – 09/28/26: From $257
    21

    Mo

  • GSP–CMH, 09/22/26 – 09/29/26: From $279
    22

    Tu

  • GSP–CMH: cmp-view-offers-disclaimer. Find Offers
    23

    We

  • GSP–CMH: cmp-view-offers-disclaimer. Find Offers
    24

    Th

  • GSP–CMH, 09/25/26 – 10/02/26: From $307
    25

    Fr

    • range$257-$773

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Greenville to Columbus flights

    $
    keyboard_arrow_down

    Greenville (GSP)to

    Columbus (CMH)
    09/21/26 - 09/28/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 4 hours ago

    Greenville (GSP)to

    Columbus (CMH)
    11/02/26 - 11/09/26

    Round trip

    Economy

    from
    $257Fare subject to changes
    Updated: 4 hours ago

    Greenville (GSP)to

    Columbus (CMH)
    11/16/26 - 11/23/26

    Round trip

    Economy

    from
    $278Fare subject to changes
    Updated: 4 hours ago

    Greenville (GSP)to

    Columbus (CMH)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 4 hours ago

    Greenville (GSP)to

    Columbus (CMH)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 4 hours ago

    Greenville (GSP)to

    Columbus (CMH)
    09/26/26 - 10/03/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 4 hours ago

    Greenville (GSP)to

    Columbus (CMH)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 4 hours ago

    Greenville (GSP)to

    Columbus (CMH)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Greenville to Columbus

    Looking for lower fares on your trip from Greenville to Columbus? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Greenville to Columbus