American Airlines flights from Jacksonville to San Francisco

Recent searches for flights from Jacksonville to San Francisco

Sep 2026
From$521*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$371*
Updated: 2 hours ago
Round tripIEconomy
Nov 2026
From$371*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $371
cmp-daily-histogram-bars-legend-max-price-aria-label $1.2K
Displaying fares for September-2026
  • JAX–SFO: cmp-view-offers-disclaimer. Find Offers
    14

    Mo

    SEP

  • JAX–SFO, 09/15/26 – 09/22/26: From $1,017
    15

    Tu

  • JAX–SFO, 09/16/26 – 09/23/26: From $1,055
    16

    We

  • JAX–SFO, 09/17/26 – 09/24/26: From $1,173
    17

    Th

  • JAX–SFO, 09/18/26 – 09/25/26: From $1,136
    18

    Fr

  • JAX–SFO, 09/19/26 – 09/26/26: From $1,017
    19

    Sa

  • JAX–SFO, 09/20/26 – 09/27/26: From $1,165
    20

    Su

  • JAX–SFO, 09/21/26 – 09/28/26: From $941
    21

    Mo

  • JAX–SFO, 09/22/26 – 09/29/26: From $939
    22

    Tu

  • JAX–SFO, 09/23/26 – 09/30/26: From $941
    23

    We

  • JAX–SFO, 09/24/26 – 10/01/26: From $941
    24

    Th

  • JAX–SFO, 09/25/26 – 10/02/26: From $941
    25

    Fr

  • JAX–SFO, 09/26/26 – 10/03/26: From $941
    26

    Sa

  • JAX–SFO, 09/27/26 – 10/04/26: From $941
    27

    Su

  • JAX–SFO, 09/28/26 – 10/07/26: From $521
    28

    Mo

  • JAX–SFO, 09/29/26 – 10/06/26: From $530
    29

    Tu

  • JAX–SFO, 09/30/26 – 10/07/26: From $530
    30

    We

  • JAX–SFO, 10/01/26 – 10/08/26: From $672
    01

    Th

    OCT

  • JAX–SFO, 10/02/26 – 10/09/26: From $583
    02

    Fr

  • JAX–SFO, 10/03/26 – 10/10/26: From $530
    03

    Sa

  • JAX–SFO, 10/04/26 – 10/06/26: From $530
    04

    Su

  • JAX–SFO, 10/05/26 – 10/12/26: From $423
    05

    Mo

  • JAX–SFO, 10/06/26 – 10/13/26: From $371
    06

    Tu

  • JAX–SFO, 10/07/26 – 10/14/26: From $371
    07

    We

  • JAX–SFO, 10/08/26 – 10/15/26: From $631
    08

    Th

  • JAX–SFO, 10/09/26 – 10/16/26: From $477
    09

    Fr

  • JAX–SFO, 10/10/26 – 10/17/26: From $371
    10

    Sa

  • JAX–SFO, 10/11/26 – 10/18/26: From $631
    11

    Su

  • JAX–SFO: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • JAX–SFO: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

    • range$371-$1,173

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Jacksonville to San Francisco flights

    $
    keyboard_arrow_down

    Jacksonville (JAX)to

    San Francisco (SFO)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $371Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Jacksonville to San Francisco

    Looking for lower fares on your trip from Jacksonville to San Francisco? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Jacksonville to San Francisco