American Airlines flights from Jacksonville to San Francisco

Recent searches for flights from Jacksonville to San Francisco

Aug 2026
From$434*
Updated: 4 hours ago
Round tripIEconomy
Sep 2026
From$411*
Updated: 25 minutes ago
Round tripIEconomy
Oct 2026
From$457*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $427
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for August-2026
  • JAX–SFO, 08/05/26 – 08/12/26: From $975
    05

    We

    AUG

  • JAX–SFO, 08/06/26 – 08/13/26: From $1,085
    06

    Th

  • JAX–SFO, 08/07/26 – 08/14/26: From $1,085
    07

    Fr

  • JAX–SFO, 08/08/26 – 08/15/26: From $977
    08

    Sa

  • JAX–SFO, 08/09/26 – 08/16/26: From $1,131
    09

    Su

  • JAX–SFO, 08/10/26 – 08/17/26: From $1,076
    10

    Mo

  • JAX–SFO, 08/11/26 – 08/18/26: From $747
    11

    Tu

  • JAX–SFO, 08/12/26 – 08/19/26: From $812
    12

    We

  • JAX–SFO, 08/13/26 – 08/20/26: From $921
    13

    Th

  • JAX–SFO, 08/14/26 – 08/21/26: From $921
    14

    Fr

  • JAX–SFO, 08/15/26 – 08/22/26: From $802
    15

    Sa

  • JAX–SFO, 08/16/26 – 08/23/26: From $921
    16

    Su

  • JAX–SFO, 08/17/26 – 08/22/26: From $761
    17

    Mo

  • JAX–SFO, 08/18/26 – 08/25/26: From $517
    18

    Tu

  • JAX–SFO, 08/19/26 – 08/26/26: From $517
    19

    We

  • JAX–SFO, 08/20/26 – 08/27/26: From $563
    20

    Th

  • JAX–SFO, 08/21/26 – 08/24/26: From $507
    21

    Fr

  • JAX–SFO, 08/22/26 – 08/29/26: From $537
    22

    Sa

  • JAX–SFO, 08/23/26 – 08/30/26: From $662
    23

    Su

  • JAX–SFO, 08/24/26 – 08/31/26: From $563
    24

    Mo

  • JAX–SFO, 08/25/26 – 09/01/26: From $457
    25

    Tu

  • JAX–SFO, 08/26/26 – 09/02/26: From $457
    26

    We

  • JAX–SFO, 08/27/26 – 09/03/26: From $457
    27

    Th

  • JAX–SFO, 08/28/26 – 09/04/26: From $533
    28

    Fr

  • JAX–SFO, 08/29/26 – 09/05/26: From $434
    29

    Sa

  • JAX–SFO, 08/30/26 – 09/06/26: From $533
    30

    Su

  • JAX–SFO, 08/31/26 – 09/07/26: From $457
    31

    Mo

  • JAX–SFO: cmp-view-offers-disclaimer. Find Offers
    01

    Tu

    SEP

  • JAX–SFO, 09/02/26 – 09/05/26: From $427
    02

    We

  • JAX–SFO, 09/03/26 – 09/09/26: From $439
    03

    Th

  • JAX–SFO, 09/04/26 – 09/11/26: From $472
    04

    Fr

    • range$427-$1,131

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Jacksonville to San Francisco flights

    $
    keyboard_arrow_down

    Jacksonville (JAX)to

    San Francisco (SFO)
    09/05/26 - 09/06/26

    Round trip

    Economy

    from
    $411Fare subject to changes
    Updated: 24 minutes ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $416Fare subject to changes
    Updated: 4 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    09/02/26 - 09/05/26

    Round trip

    Economy

    from
    $427Fare subject to changes
    Updated: 1 hour ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $434Fare subject to changes
    Updated: 4 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    09/11/26 - 09/14/26

    Round trip

    Economy

    from
    $434Fare subject to changes
    Updated: 12 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    09/09/26 - 09/16/26

    Round trip

    Economy

    from
    $439Fare subject to changes
    Updated: 4 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $439Fare subject to changes
    Updated: 4 hours ago

    Jacksonville (JAX)to

    San Francisco (SFO)
    09/03/26 - 09/09/26

    Round trip

    Economy

    from
    $439Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Jacksonville to San Francisco

    Looking for lower fares on your trip from Jacksonville to San Francisco? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Jacksonville to San Francisco