American Airlines flights from Saint Louis to San Francisco

Recent searches for flights from Saint Louis to San Francisco

Aug 2026
From$387*
Updated: 9 hours ago
Round tripIEconomy
Sep 2026
From$395*
Updated: 9 hours ago
Round tripIEconomy
Oct 2026
From$397*
Updated: 9 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $387
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for August-2026
  • STL–SFO, 08/06/26 – 08/13/26: From $1,101
    06

    Th

    AUG

  • STL–SFO, 08/07/26 – 08/14/26: From $1,073
    07

    Fr

  • STL–SFO, 08/08/26 – 08/15/26: From $933
    08

    Sa

  • STL–SFO, 08/09/26 – 08/16/26: From $1,101
    09

    Su

  • STL–SFO, 08/10/26 – 08/17/26: From $1,073
    10

    Mo

  • STL–SFO, 08/11/26 – 08/18/26: From $933
    11

    Tu

  • STL–SFO, 08/12/26 – 08/19/26: From $794
    12

    We

  • STL–SFO, 08/13/26 – 08/20/26: From $854
    13

    Th

  • STL–SFO, 08/14/26 – 08/23/26: From $637
    14

    Fr

  • STL–SFO, 08/15/26 – 08/23/26: From $637
    15

    Sa

  • STL–SFO, 08/16/26 – 08/23/26: From $870
    16

    Su

  • STL–SFO, 08/17/26 – 08/24/26: From $877
    17

    Mo

  • STL–SFO, 08/18/26 – 08/25/26: From $794
    18

    Tu

  • STL–SFO, 08/19/26 – 08/26/26: From $518
    19

    We

  • STL–SFO, 08/20/26 – 08/27/26: From $526
    20

    Th

  • STL–SFO, 08/21/26 – 08/28/26: From $563
    21

    Fr

  • STL–SFO, 08/22/26 – 08/29/26: From $518
    22

    Sa

  • STL–SFO, 08/23/26 – 08/30/26: From $599
    23

    Su

  • STL–SFO, 08/24/26 – 08/31/26: From $526
    24

    Mo

  • STL–SFO, 08/25/26 – 09/13/26: From $478
    25

    Tu

  • STL–SFO, 08/26/26 – 09/02/26: From $405
    26

    We

  • STL–SFO, 08/27/26 – 09/03/26: From $405
    27

    Th

  • STL–SFO, 08/28/26 – 09/04/26: From $487
    28

    Fr

  • STL–SFO, 08/29/26 – 09/05/26: From $387
    29

    Sa

  • STL–SFO, 08/30/26 – 09/06/26: From $468
    30

    Su

  • STL–SFO, 08/31/26 – 09/07/26: From $450
    31

    Mo

  • STL–SFO, 09/01/26 – 09/08/26: From $405
    01

    Tu

    SEP

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    02

    We

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    03

    Th

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    04

    Fr

  • STL–SFO, 09/05/26 – 09/12/26: From $395
    05

    Sa

    • range$387-$1,101

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Saint Louis to San Francisco flights

    $
    keyboard_arrow_down

    Saint Louis (STL)to

    San Francisco (SFO)
    08/29/26 - 09/05/26

    Round trip

    Economy

    from
    $387Fare subject to changes
    Updated: 9 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $395Fare subject to changes
    Updated: 9 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 9 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 9 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 9 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 9 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 9 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $397Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Saint Louis to San Francisco

    Looking for lower fares on your trip from Saint Louis to San Francisco? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Saint Louis to San Francisco