American Airlines flights from Saint Louis to San Francisco

Recent searches for flights from Saint Louis to San Francisco

Sep 2026
From$521*
Updated: 6 hours ago
Round tripIEconomy
Oct 2026
From$363*
Updated: 6 hours ago
Round tripIEconomy
Nov 2026
From$363*
Updated: 6 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $363
cmp-daily-histogram-bars-legend-max-price-aria-label $1.2K
Displaying fares for September-2026
  • STL–SFO, 09/15/26 – 09/22/26: From $1,013
    15

    Tu

    SEP

  • STL–SFO, 09/16/26 – 09/23/26: From $1,013
    16

    We

  • STL–SFO, 09/17/26 – 09/24/26: From $1,148
    17

    Th

  • STL–SFO, 09/18/26 – 09/25/26: From $1,159
    18

    Fr

  • STL–SFO, 09/19/26 – 09/26/26: From $1,028
    19

    Sa

  • STL–SFO, 09/20/26 – 09/27/26: From $1,159
    20

    Su

  • STL–SFO, 09/21/26 – 09/28/26: From $916
    21

    Mo

  • STL–SFO, 09/22/26 – 09/29/26: From $846
    22

    Tu

  • STL–SFO, 09/23/26 – 09/30/26: From $846
    23

    We

  • STL–SFO, 09/24/26 – 10/01/26: From $916
    24

    Th

  • STL–SFO, 09/25/26 – 10/02/26: From $916
    25

    Fr

  • STL–SFO, 09/26/26 – 10/03/26: From $854
    26

    Sa

  • STL–SFO, 09/27/26 – 10/04/26: From $916
    27

    Su

  • STL–SFO, 09/28/26 – 10/05/26: From $547
    28

    Mo

  • STL–SFO, 09/29/26 – 10/06/26: From $521
    29

    Tu

  • STL–SFO, 09/30/26 – 10/07/26: From $521
    30

    We

  • STL–SFO, 10/01/26 – 10/08/26: From $547
    01

    Th

    OCT

  • STL–SFO, 10/02/26 – 10/09/26: From $573
    02

    Fr

  • STL–SFO, 10/03/26 – 10/10/26: From $521
    03

    Sa

  • STL–SFO, 10/04/26 – 10/11/26: From $639
    04

    Su

  • STL–SFO, 10/05/26 – 10/12/26: From $415
    05

    Mo

  • STL–SFO, 10/06/26 – 10/13/26: From $363
    06

    Tu

  • STL–SFO, 10/07/26 – 10/14/26: From $363
    07

    We

  • STL–SFO, 10/08/26 – 10/15/26: From $415
    08

    Th

  • STL–SFO, 10/09/26 – 10/16/26: From $467
    09

    Fr

  • STL–SFO, 10/10/26 – 10/17/26: From $363
    10

    Sa

  • STL–SFO, 10/11/26 – 10/18/26: From $599
    11

    Su

  • STL–SFO, 10/12/26 – 10/14/26: From $389
    12

    Mo

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    14

    We

    • range$363-$1,159

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Saint Louis to San Francisco flights

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    Saint Louis (STL)to

    San Francisco (SFO)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    Saint Louis (STL)to

    San Francisco (SFO)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 6 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Saint Louis to San Francisco

    Looking for lower fares on your trip from Saint Louis to San Francisco? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Saint Louis to San Francisco