American Airlines flights from Key West to Sioux Falls

Recent searches for flights from Key West to Sioux Falls

Sep 2026
From$356*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$333*
Updated: 3 hours ago
Round tripIEconomy
Nov 2026
From$346*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $356
cmp-daily-histogram-bars-legend-max-price-aria-label $1.3K
Displaying fares for September-2026
  • EYW–FSD: cmp-view-offers-disclaimer. Find Offers
    02

    We

    SEP

  • EYW–FSD, 09/03/26 – 09/10/26: From $596
    03

    Th

  • EYW–FSD, 09/04/26 – 09/11/26: From $855
    04

    Fr

  • EYW–FSD, 09/05/26 – 09/12/26: From $444
    05

    Sa

  • EYW–FSD, 09/06/26 – 09/13/26: From $642
    06

    Su

  • EYW–FSD, 09/07/26 – 09/14/26: From $1,298
    07

    Mo

  • EYW–FSD, 09/08/26 – 09/15/26: From $444
    08

    Tu

  • EYW–FSD, 09/09/26 – 09/16/26: From $391
    09

    We

  • EYW–FSD, 09/10/26 – 09/17/26: From $734
    10

    Th

  • EYW–FSD, 09/11/26 – 09/18/26: From $732
    11

    Fr

  • EYW–FSD, 09/12/26 – 09/19/26: From $644
    12

    Sa

  • EYW–FSD, 09/13/26 – 09/20/26: From $848
    13

    Su

  • EYW–FSD, 09/14/26 – 09/21/26: From $678
    14

    Mo

  • EYW–FSD, 09/15/26 – 09/22/26: From $444
    15

    Tu

  • EYW–FSD, 09/16/26 – 09/23/26: From $530
    16

    We

  • EYW–FSD, 09/17/26 – 09/24/26: From $732
    17

    Th

  • EYW–FSD, 09/18/26 – 09/25/26: From $714
    18

    Fr

  • EYW–FSD, 09/19/26 – 09/26/26: From $600
    19

    Sa

  • EYW–FSD, 09/20/26 – 09/27/26: From $960
    20

    Su

  • EYW–FSD, 09/21/26 – 09/28/26: From $633
    21

    Mo

  • EYW–FSD, 09/22/26 – 09/29/26: From $404
    22

    Tu

  • EYW–FSD, 09/23/26 – 09/30/26: From $473
    23

    We

  • EYW–FSD, 09/24/26 – 10/01/26: From $690
    24

    Th

  • EYW–FSD, 09/25/26 – 10/02/26: From $643
    25

    Fr

  • EYW–FSD, 09/26/26 – 10/03/26: From $703
    26

    Sa

  • EYW–FSD, 09/27/26 – 10/04/26: From $1,038
    27

    Su

  • EYW–FSD, 09/28/26 – 10/05/26: From $702
    28

    Mo

  • EYW–FSD, 09/29/26 – 10/06/26: From $356
    29

    Tu

  • EYW–FSD: cmp-view-offers-disclaimer. Find Offers
    30

    We

  • EYW–FSD: cmp-view-offers-disclaimer. Find Offers
    01

    Th

    OCT

    • range$356-$1,298

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Key West to Sioux Falls flights

    $
    keyboard_arrow_down

    Key West (EYW)to

    Sioux Falls (FSD)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 3 hours ago

    Key West (EYW)to

    Sioux Falls (FSD)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 3 hours ago

    Key West (EYW)to

    Sioux Falls (FSD)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $338Fare subject to changes
    Updated: 3 hours ago

    Key West (EYW)to

    Sioux Falls (FSD)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $346Fare subject to changes
    Updated: 3 hours ago

    Key West (EYW)to

    Sioux Falls (FSD)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $356Fare subject to changes
    Updated: 3 hours ago

    Key West (EYW)to

    Sioux Falls (FSD)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $356Fare subject to changes
    Updated: 3 hours ago

    Key West (EYW)to

    Sioux Falls (FSD)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $386Fare subject to changes
    Updated: 3 hours ago

    Key West (EYW)to

    Sioux Falls (FSD)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $391Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Key West to Sioux Falls

    Looking for lower fares on your trip from Key West to Sioux Falls? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Key West to Sioux Falls