American Airlines flights from Portland, ME to Sioux Falls

Recent searches for flights from Portland, ME to Sioux Falls

Sep 2026
From$404*
Updated: 10 hours ago
Round tripIEconomy
Oct 2026
From$358*
Updated: 10 hours ago
Round tripIEconomy
Nov 2026
From$363*
Updated: 10 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $404
cmp-daily-histogram-bars-legend-max-price-aria-label $939
Displaying fares for September-2026
  • PWM–FSD, 09/12/26 – 09/19/26: From $464
    12

    Sa

    SEP

  • PWM–FSD, 09/13/26 – 09/20/26: From $912
    13

    Su

  • PWM–FSD, 09/14/26 – 09/21/26: From $939
    14

    Mo

  • PWM–FSD, 09/15/26 – 09/22/26: From $464
    15

    Tu

  • PWM–FSD, 09/16/26 – 09/23/26: From $792
    16

    We

  • PWM–FSD, 09/17/26 – 09/24/26: From $925
    17

    Th

  • PWM–FSD, 09/18/26 – 09/25/26: From $815
    18

    Fr

  • PWM–FSD, 09/19/26 – 09/26/26: From $454
    19

    Sa

  • PWM–FSD, 09/20/26 – 09/27/26: From $934
    20

    Su

  • PWM–FSD, 09/21/26 – 09/28/26: From $815
    21

    Mo

  • PWM–FSD, 09/22/26 – 09/29/26: From $603
    22

    Tu

  • PWM–FSD, 09/23/26 – 09/30/26: From $676
    23

    We

  • PWM–FSD, 09/24/26 – 10/01/26: From $745
    24

    Th

  • PWM–FSD, 09/25/26 – 10/02/26: From $526
    25

    Fr

  • PWM–FSD, 09/26/26 – 10/03/26: From $454
    26

    Sa

  • PWM–FSD, 09/27/26 – 10/04/26: From $829
    27

    Su

  • PWM–FSD, 09/28/26 – 10/05/26: From $745
    28

    Mo

  • PWM–FSD, 09/29/26 – 10/06/26: From $404
    29

    Tu

  • PWM–FSD, 09/30/26 – 10/07/26: From $404
    30

    We

  • PWM–FSD, 10/01/26 – 10/08/26: From $815
    01

    Th

    OCT

  • PWM–FSD, 10/02/26 – 10/09/26: From $645
    02

    Fr

  • PWM–FSD, 10/03/26 – 10/10/26: From $419
    03

    Sa

  • PWM–FSD, 10/04/26 – 10/11/26: From $903
    04

    Su

  • PWM–FSD, 10/05/26 – 10/12/26: From $788
    05

    Mo

  • PWM–FSD, 10/06/26 – 10/13/26: From $416
    06

    Tu

  • PWM–FSD, 10/07/26 – 10/14/26: From $469
    07

    We

  • PWM–FSD, 10/08/26 – 10/15/26: From $623
    08

    Th

  • PWM–FSD, 10/09/26 – 10/16/26: From $576
    09

    Fr

  • PWM–FSD: cmp-view-offers-disclaimer. Find Offers
    10

    Sa

  • PWM–FSD: cmp-view-offers-disclaimer. Find Offers
    11

    Su

    • range$404-$939

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Portland, ME to Sioux Falls flights

    $
    keyboard_arrow_down

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $358Fare subject to changes
    Updated: 10 hours ago

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $358Fare subject to changes
    Updated: 10 hours ago

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $358Fare subject to changes
    Updated: 10 hours ago

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $358Fare subject to changes
    Updated: 5 hours ago

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $358Fare subject to changes
    Updated: 10 hours ago

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 10 hours ago

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 10 hours ago

    Portland, ME (PWM)to

    Sioux Falls (FSD)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $363Fare subject to changes
    Updated: 10 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Portland, ME to Sioux Falls

    Looking for lower fares on your trip from Portland, ME to Sioux Falls? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Portland, ME to Sioux Falls