American Airlines flights from Myrtle Beach to Detroit

Recent searches for flights from Myrtle Beach to Detroit

Sep 2026
From$394*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$344*
Updated: 4 hours ago
Round tripIEconomy
Nov 2026
From$349*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $394
cmp-daily-histogram-bars-legend-max-price-aria-label $754
Displaying fares for September-2026
  • MYR–DTW: cmp-view-offers-disclaimer. Find Offers
    04

    Fr

    SEP

  • MYR–DTW, 09/05/26 – 09/12/26: From $754
    05

    Sa

  • MYR–DTW, 09/06/26 – 09/13/26: From $754
    06

    Su

  • MYR–DTW, 09/07/26 – 09/14/26: From $754
    07

    Mo

  • MYR–DTW, 09/08/26 – 09/15/26: From $754
    08

    Tu

  • MYR–DTW, 09/09/26 – 09/16/26: From $754
    09

    We

  • MYR–DTW, 09/10/26 – 09/17/26: From $754
    10

    Th

  • MYR–DTW, 09/11/26 – 09/18/26: From $639
    11

    Fr

  • MYR–DTW, 09/12/26 – 09/19/26: From $639
    12

    Sa

  • MYR–DTW, 09/13/26 – 09/20/26: From $639
    13

    Su

  • MYR–DTW, 09/14/26 – 09/21/26: From $639
    14

    Mo

  • MYR–DTW, 09/15/26 – 09/22/26: From $639
    15

    Tu

  • MYR–DTW, 09/16/26 – 09/23/26: From $639
    16

    We

  • MYR–DTW, 09/17/26 – 09/24/26: From $639
    17

    Th

  • MYR–DTW, 09/18/26 – 09/25/26: From $499
    18

    Fr

  • MYR–DTW, 09/19/26 – 09/26/26: From $499
    19

    Sa

  • MYR–DTW, 09/20/26 – 09/27/26: From $499
    20

    Su

  • MYR–DTW, 09/21/26 – 09/28/26: From $499
    21

    Mo

  • MYR–DTW, 09/22/26 – 09/29/26: From $499
    22

    Tu

  • MYR–DTW, 09/23/26 – 09/30/26: From $499
    23

    We

  • MYR–DTW, 09/24/26 – 10/01/26: From $639
    24

    Th

  • MYR–DTW, 09/25/26 – 10/02/26: From $560
    25

    Fr

  • MYR–DTW, 09/26/26 – 10/03/26: From $449
    26

    Sa

  • MYR–DTW, 09/27/26 – 10/04/26: From $394
    27

    Su

  • MYR–DTW, 09/28/26 – 10/05/26: From $394
    28

    Mo

  • MYR–DTW, 09/29/26 – 10/06/26: From $394
    29

    Tu

  • MYR–DTW, 09/30/26 – 10/07/26: From $394
    30

    We

  • MYR–DTW, 10/01/26 – 10/08/26: From $474
    01

    Th

    OCT

  • MYR–DTW: cmp-view-offers-disclaimer. Find Offers
    02

    Fr

  • MYR–DTW: cmp-view-offers-disclaimer. Find Offers
    03

    Sa

    • range$394-$754

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Myrtle Beach to Detroit flights

    $
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    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/05/26 - 10/12/26

    Round trip

    Economy

    from
    $344Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $344Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $344Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $344Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/09/26 - 10/16/26

    Round trip

    Economy

    from
    $344Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/16/26 - 10/23/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Detroit (DTW)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Myrtle Beach to Detroit

    Looking for lower fares on your trip from Myrtle Beach to Detroit? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Myrtle Beach to Detroit