American Airlines flights from Myrtle Beach to Indianapolis

Recent searches for flights from Myrtle Beach to Indianapolis

Aug 2026
From$612*
Updated: 2 hours ago
Round tripIEconomy
Sep 2026
From$271*
Updated: 2 hours ago
Round tripIEconomy
Oct 2026
From$271*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $271
cmp-daily-histogram-bars-legend-max-price-aria-label $742
Displaying fares for August-2026
  • MYR–IND: cmp-view-offers-disclaimer. Find Offers
    21

    Fr

    AUG

  • MYR–IND, 08/22/26 – 08/29/26: From $742
    22

    Sa

  • MYR–IND, 08/23/26 – 08/30/26: From $742
    23

    Su

  • MYR–IND, 08/24/26 – 08/31/26: From $742
    24

    Mo

  • MYR–IND, 08/25/26 – 09/01/26: From $703
    25

    Tu

  • MYR–IND, 08/26/26 – 09/02/26: From $742
    26

    We

  • MYR–IND, 08/27/26 – 09/03/26: From $742
    27

    Th

  • MYR–IND, 08/28/26 – 09/04/26: From $722
    28

    Fr

  • MYR–IND, 08/29/26 – 09/05/26: From $612
    29

    Sa

  • MYR–IND, 08/30/26 – 09/06/26: From $612
    30

    Su

  • MYR–IND, 08/31/26 – 09/07/26: From $612
    31

    Mo

  • MYR–IND, 09/01/26 – 09/05/26: From $551
    01

    Tu

    SEP

  • MYR–IND, 09/02/26 – 09/06/26: From $577
    02

    We

  • MYR–IND, 09/03/26 – 09/10/26: From $612
    03

    Th

  • MYR–IND, 09/04/26 – 09/11/26: From $390
    04

    Fr

  • MYR–IND, 09/05/26 – 09/12/26: From $271
    05

    Sa

  • MYR–IND, 09/06/26 – 09/13/26: From $447
    06

    Su

  • MYR–IND, 09/07/26 – 09/14/26: From $564
    07

    Mo

  • MYR–IND, 09/08/26 – 09/15/26: From $395
    08

    Tu

  • MYR–IND, 09/09/26 – 09/16/26: From $374
    09

    We

  • MYR–IND, 09/10/26 – 09/17/26: From $395
    10

    Th

  • MYR–IND, 09/11/26 – 09/18/26: From $311
    11

    Fr

  • MYR–IND, 09/12/26 – 09/19/26: From $271
    12

    Sa

  • MYR–IND, 09/13/26 – 09/20/26: From $407
    13

    Su

  • MYR–IND, 09/14/26 – 09/21/26: From $271
    14

    Mo

  • MYR–IND, 09/15/26 – 09/22/26: From $271
    15

    Tu

  • MYR–IND, 09/16/26 – 09/23/26: From $271
    16

    We

  • MYR–IND, 09/17/26 – 09/24/26: From $311
    17

    Th

  • MYR–IND: cmp-view-offers-disclaimer. Find Offers
    18

    Fr

  • MYR–IND: cmp-view-offers-disclaimer. Find Offers
    19

    Sa

  • MYR–IND: cmp-view-offers-disclaimer. Find Offers
    20

    Su

    • range$271-$742

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Myrtle Beach to Indianapolis flights

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    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/26/26 - 11/02/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    Myrtle Beach (MYR)to

    Indianapolis (IND)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $271Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Myrtle Beach to Indianapolis

    Looking for lower fares on your trip from Myrtle Beach to Indianapolis? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Myrtle Beach to Indianapolis