American Airlines flights from San Francisco to Indianapolis

Recent searches for flights from San Francisco to Indianapolis

Aug 2026
From$634*
Updated: 19 hours ago
Round tripIEconomy
Sep 2026
From$308*
Updated: 19 hours ago
Round tripIEconomy
Oct 2026
From$298*
Updated: 20 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $308
cmp-daily-histogram-bars-legend-max-price-aria-label $634
Displaying fares for August-2026
  • SFO–IND, 08/26/26 – 09/02/26: From $634
    26

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    AUG

  • SFO–IND, 08/27/26 – 09/03/26: From $634
    27

    Th

  • SFO–IND, 08/28/26 – 09/04/26: From $634
    28

    Fr

  • SFO–IND, 08/29/26 – 09/05/26: From $634
    29

    Sa

  • SFO–IND, 08/30/26 – 09/06/26: From $634
    30

    Su

  • SFO–IND, 08/31/26 – 09/07/26: From $634
    31

    Mo

  • SFO–IND, 09/01/26 – 09/08/26: From $634
    01

    Tu

    SEP

  • SFO–IND, 09/02/26 – 09/09/26: From $509
    02

    We

  • SFO–IND, 09/03/26 – 09/10/26: From $509
    03

    Th

  • SFO–IND, 09/04/26 – 09/11/26: From $509
    04

    Fr

  • SFO–IND, 09/05/26 – 09/12/26: From $509
    05

    Sa

  • SFO–IND, 09/06/26 – 09/13/26: From $509
    06

    Su

  • SFO–IND, 09/07/26 – 09/14/26: From $509
    07

    Mo

  • SFO–IND, 09/08/26 – 09/15/26: From $509
    08

    Tu

  • SFO–IND, 09/09/26 – 09/16/26: From $404
    09

    We

  • SFO–IND, 09/10/26 – 09/17/26: From $404
    10

    Th

  • SFO–IND, 09/11/26 – 09/18/26: From $414
    11

    Fr

  • SFO–IND, 09/12/26 – 09/19/26: From $404
    12

    Sa

  • SFO–IND, 09/13/26 – 09/20/26: From $414
    13

    Su

  • SFO–IND, 09/14/26 – 09/21/26: From $404
    14

    Mo

  • SFO–IND, 09/15/26 – 09/22/26: From $404
    15

    Tu

  • SFO–IND, 09/16/26 – 09/23/26: From $359
    16

    We

  • SFO–IND, 09/17/26 – 09/20/26: From $308
    17

    Th

  • SFO–IND, 09/18/26 – 09/25/26: From $379
    18

    Fr

  • SFO–IND, 09/19/26 – 09/26/26: From $359
    19

    Sa

  • SFO–IND, 09/20/26 – 09/27/26: From $379
    20

    Su

  • SFO–IND, 09/21/26 – 09/28/26: From $359
    21

    Mo

  • SFO–IND, 09/22/26 – 09/29/26: From $359
    22

    Tu

  • SFO–IND: cmp-view-offers-disclaimer. Find Offers
    23

    We

  • SFO–IND: cmp-view-offers-disclaimer. Find Offers
    24

    Th

  • SFO–IND, 09/25/26 – 10/02/26: From $379
    25

    Fr

    • range$308-$634

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Francisco to Indianapolis flights

    $
    keyboard_arrow_down

    San Francisco (SFO)to

    Indianapolis (IND)
    10/24/26 - 10/30/26

    Round trip

    Economy

    from
    $298Fare subject to changes
    Updated: 20 hours ago

    San Francisco (SFO)to

    Indianapolis (IND)
    11/18/26 - 11/22/26

    Round trip

    Economy

    from
    $308Fare subject to changes
    Updated: 18 hours ago

    San Francisco (SFO)to

    Indianapolis (IND)
    09/17/26 - 09/20/26

    Round trip

    Economy

    from
    $308Fare subject to changes
    Updated: 19 hours ago

    San Francisco (SFO)to

    Indianapolis (IND)
    11/05/26 - 11/08/26

    Round trip

    Economy

    from
    $308Fare subject to changes
    Updated: 18 hours ago

    San Francisco (SFO)to

    Indianapolis (IND)
    10/04/26 - 10/07/26

    Round trip

    Economy

    from
    $332Fare subject to changes
    Updated: 23 hours ago

    San Francisco (SFO)to

    Indianapolis (IND)
    09/27/26 - 09/29/26

    Round trip

    Economy

    from
    $342Fare subject to changes
    Updated: 19 hours ago

    San Francisco (SFO)to

    Indianapolis (IND)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 9 hours ago

    San Francisco (SFO)to

    Indianapolis (IND)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $359Fare subject to changes
    Updated: 9 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from San Francisco to Indianapolis

    Looking for lower fares on your trip from San Francisco to Indianapolis? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from San Francisco to Indianapolis