American Airlines flights from Key West to Indianapolis

Recent searches for flights from Key West to Indianapolis

Aug 2026
From$419*
Updated: 4 hours ago
Round tripIEconomy
Sep 2026
From$309*
Updated: 19 hours ago
Round tripIEconomy
Oct 2026
From$309*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $309
cmp-daily-histogram-bars-legend-max-price-aria-label $969
Displaying fares for August-2026
  • EYW–IND, 08/23/26 – 08/30/26: From $573
    23

    Su

    AUG

  • EYW–IND, 08/24/26 – 08/31/26: From $573
    24

    Mo

  • EYW–IND, 08/25/26 – 09/01/26: From $419
    25

    Tu

  • EYW–IND, 08/26/26 – 09/02/26: From $419
    26

    We

  • EYW–IND, 08/27/26 – 09/03/26: From $682
    27

    Th

  • EYW–IND, 08/28/26 – 09/04/26: From $805
    28

    Fr

  • EYW–IND, 08/29/26 – 09/05/26: From $466
    29

    Sa

  • EYW–IND, 08/30/26 – 09/06/26: From $682
    30

    Su

  • EYW–IND, 08/31/26 – 09/07/26: From $573
    31

    Mo

  • EYW–IND, 09/01/26 – 09/08/26: From $419
    01

    Tu

    SEP

  • EYW–IND, 09/02/26 – 09/09/26: From $419
    02

    We

  • EYW–IND, 09/03/26 – 09/10/26: From $608
    03

    Th

  • EYW–IND, 09/04/26 – 09/11/26: From $573
    04

    Fr

  • EYW–IND, 09/05/26 – 09/12/26: From $364
    05

    Sa

  • EYW–IND, 09/06/26 – 09/13/26: From $644
    06

    Su

  • EYW–IND, 09/07/26 – 09/14/26: From $969
    07

    Mo

  • EYW–IND, 09/08/26 – 09/15/26: From $490
    08

    Tu

  • EYW–IND, 09/09/26 – 09/16/26: From $443
    09

    We

  • EYW–IND, 09/10/26 – 09/17/26: From $550
    10

    Th

  • EYW–IND, 09/11/26 – 09/18/26: From $441
    11

    Fr

  • EYW–IND, 09/12/26 – 09/19/26: From $364
    12

    Sa

  • EYW–IND, 09/13/26 – 09/20/26: From $767
    13

    Su

  • EYW–IND, 09/14/26 – 09/21/26: From $478
    14

    Mo

  • EYW–IND, 09/15/26 – 09/22/26: From $364
    15

    Tu

  • EYW–IND, 09/16/26 – 09/23/26: From $419
    16

    We

  • EYW–IND, 09/17/26 – 09/24/26: From $649
    17

    Th

  • EYW–IND, 09/18/26 – 09/25/26: From $535
    18

    Fr

  • EYW–IND, 09/19/26 – 09/26/26: From $490
    19

    Sa

  • EYW–IND: cmp-view-offers-disclaimer. Find Offers
    20

    Su

  • EYW–IND: cmp-view-offers-disclaimer. Find Offers
    21

    Mo

  • EYW–IND, 09/22/26 – 09/29/26: From $309
    22

    Tu

    • range$309-$969

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Key West to Indianapolis flights

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    keyboard_arrow_down

    Key West (EYW)to

    Indianapolis (IND)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 4 hours ago

    Key West (EYW)to

    Indianapolis (IND)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 19 hours ago

    Key West (EYW)to

    Indianapolis (IND)
    09/23/26 - 09/30/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 4 hours ago

    Key West (EYW)to

    Indianapolis (IND)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 4 hours ago

    Key West (EYW)to

    Indianapolis (IND)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 4 hours ago

    Key West (EYW)to

    Indianapolis (IND)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 4 hours ago

    Key West (EYW)to

    Indianapolis (IND)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 4 hours ago

    Key West (EYW)to

    Indianapolis (IND)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $309Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Key West to Indianapolis

    Looking for lower fares on your trip from Key West to Indianapolis? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Key West to Indianapolis