American Airlines flights from Myrtle Beach to Louisville

Recent searches for flights from Myrtle Beach to Louisville

Aug 2026
From$502*
Updated: 47 minutes ago
Round tripIEconomy
Sep 2026
From$279*
Updated: 47 minutes ago
Round tripIEconomy
Oct 2026
From$279*
Updated: 47 minutes ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $279
cmp-daily-histogram-bars-legend-max-price-aria-label $797
Displaying fares for August-2026
  • MYR–SDF, 08/22/26 – 08/29/26: From $535
    22

    Sa

    AUG

  • MYR–SDF, 08/23/26 – 08/30/26: From $672
    23

    Su

  • MYR–SDF, 08/24/26 – 08/31/26: From $672
    24

    Mo

  • MYR–SDF, 08/25/26 – 09/01/26: From $535
    25

    Tu

  • MYR–SDF, 08/26/26 – 09/02/26: From $535
    26

    We

  • MYR–SDF, 08/27/26 – 09/03/26: From $697
    27

    Th

  • MYR–SDF, 08/28/26 – 09/04/26: From $797
    28

    Fr

  • MYR–SDF, 08/29/26 – 09/05/26: From $502
    29

    Sa

  • MYR–SDF, 08/30/26 – 09/06/26: From $593
    30

    Su

  • MYR–SDF, 08/31/26 – 09/07/26: From $593
    31

    Mo

  • MYR–SDF, 09/01/26 – 09/08/26: From $502
    01

    Tu

    SEP

  • MYR–SDF, 09/02/26 – 09/09/26: From $502
    02

    We

  • MYR–SDF, 09/03/26 – 09/10/26: From $593
    03

    Th

  • MYR–SDF, 09/04/26 – 09/11/26: From $593
    04

    Fr

  • MYR–SDF, 09/05/26 – 09/12/26: From $365
    05

    Sa

  • MYR–SDF, 09/06/26 – 09/13/26: From $491
    06

    Su

  • MYR–SDF, 09/07/26 – 09/14/26: From $523
    07

    Mo

  • MYR–SDF, 09/08/26 – 09/15/26: From $432
    08

    Tu

  • MYR–SDF, 09/09/26 – 09/16/26: From $365
    09

    We

  • MYR–SDF, 09/10/26 – 09/17/26: From $421
    10

    Th

  • MYR–SDF, 09/11/26 – 09/18/26: From $425
    11

    Fr

  • MYR–SDF, 09/12/26 – 09/19/26: From $279
    12

    Sa

  • MYR–SDF, 09/13/26 – 09/20/26: From $397
    13

    Su

  • MYR–SDF, 09/14/26 – 09/21/26: From $370
    14

    Mo

  • MYR–SDF, 09/15/26 – 09/22/26: From $279
    15

    Tu

  • MYR–SDF, 09/16/26 – 09/23/26: From $370
    16

    We

  • MYR–SDF, 09/17/26 – 09/24/26: From $370
    17

    Th

  • MYR–SDF, 09/18/26 – 09/25/26: From $380
    18

    Fr

  • MYR–SDF: cmp-view-offers-disclaimer. Find Offers
    19

    Sa

  • MYR–SDF: cmp-view-offers-disclaimer. Find Offers
    20

    Su

  • MYR–SDF, 09/21/26 – 09/28/26: From $314
    21

    Mo

    • range$279-$797

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Myrtle Beach to Louisville flights

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    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 10 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 47 minutes ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 47 minutes ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 47 minutes ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    09/28/26 - 10/05/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 47 minutes ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 47 minutes ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/07/26 - 10/14/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 47 minutes ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/15/26 - 10/22/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 47 minutes ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Myrtle Beach to Louisville

    Looking for lower fares on your trip from Myrtle Beach to Louisville? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

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    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
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    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Myrtle Beach to Louisville