American Airlines flights from Myrtle Beach to Louisville

Recent searches for flights from Myrtle Beach to Louisville

Aug 2026
From$299*
Updated: 4 hours ago
Round tripIEconomy
Sep 2026
From$289*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$299*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $299
cmp-daily-histogram-bars-legend-max-price-aria-label $697
Displaying fares for August-2026
  • MYR–SDF: cmp-view-offers-disclaimer. Find Offers
    01

    Sa

    AUG

  • MYR–SDF, 08/02/26 – 08/09/26: From $672
    02

    Su

  • MYR–SDF, 08/03/26 – 08/10/26: From $672
    03

    Mo

  • MYR–SDF, 08/04/26 – 08/11/26: From $535
    04

    Tu

  • MYR–SDF, 08/05/26 – 08/12/26: From $535
    05

    We

  • MYR–SDF, 08/06/26 – 08/13/26: From $697
    06

    Th

  • MYR–SDF, 08/07/26 – 08/14/26: From $697
    07

    Fr

  • MYR–SDF, 08/08/26 – 08/15/26: From $502
    08

    Sa

  • MYR–SDF, 08/09/26 – 08/16/26: From $593
    09

    Su

  • MYR–SDF, 08/10/26 – 08/17/26: From $547
    10

    Mo

  • MYR–SDF, 08/11/26 – 08/18/26: From $502
    11

    Tu

  • MYR–SDF, 08/12/26 – 08/19/26: From $502
    12

    We

  • MYR–SDF, 08/13/26 – 08/20/26: From $547
    13

    Th

  • MYR–SDF, 08/14/26 – 08/21/26: From $547
    14

    Fr

  • MYR–SDF, 08/15/26 – 08/22/26: From $417
    15

    Sa

  • MYR–SDF, 08/16/26 – 08/23/26: From $423
    16

    Su

  • MYR–SDF, 08/17/26 – 08/24/26: From $384
    17

    Mo

  • MYR–SDF, 08/18/26 – 08/25/26: From $314
    18

    Tu

  • MYR–SDF, 08/19/26 – 08/26/26: From $314
    19

    We

  • MYR–SDF, 08/20/26 – 08/27/26: From $338
    20

    Th

  • MYR–SDF, 08/21/26 – 08/28/26: From $353
    21

    Fr

  • MYR–SDF, 08/22/26 – 08/29/26: From $384
    22

    Sa

  • MYR–SDF, 08/23/26 – 08/30/26: From $377
    23

    Su

  • MYR–SDF, 08/24/26 – 08/31/26: From $299
    24

    Mo

  • MYR–SDF, 08/25/26 – 09/01/26: From $299
    25

    Tu

  • MYR–SDF, 08/26/26 – 09/02/26: From $299
    26

    We

  • MYR–SDF, 08/27/26 – 09/03/26: From $380
    27

    Th

  • MYR–SDF, 08/28/26 – 09/04/26: From $395
    28

    Fr

  • MYR–SDF: cmp-view-offers-disclaimer. Find Offers
    29

    Sa

  • MYR–SDF: cmp-view-offers-disclaimer. Find Offers
    30

    Su

  • MYR–SDF: cmp-view-offers-disclaimer. Find Offers
    31

    Mo

    • range$299-$697

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Myrtle Beach to Louisville flights

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    Myrtle Beach (MYR)to

    Louisville (SDF)
    09/05/26 - 09/12/26

    Round trip

    Economy

    from
    $289Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    09/03/26 - 09/10/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    09/15/26 - 09/22/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 4 hours ago

    Myrtle Beach (MYR)to

    Louisville (SDF)
    09/17/26 - 09/24/26

    Round trip

    Economy

    from
    $299Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Myrtle Beach to Louisville

    Looking for lower fares on your trip from Myrtle Beach to Louisville? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

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    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Myrtle Beach to Louisville