American Airlines flights from Portland, ME to Myrtle Beach

Recent searches for flights from Portland, ME to Myrtle Beach

Sep 2026
From$462*
Updated: 7 hours ago
Round tripIEconomy
Oct 2026
From$239*
Updated: 7 hours ago
Round tripIEconomy
Nov 2026
From$239*
Updated: 7 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $323
cmp-daily-histogram-bars-legend-max-price-aria-label $719
Displaying fares for September-2026
  • PWM–MYR, 09/15/26 – 09/22/26: From $609
    15

    Tu

    SEP

  • PWM–MYR, 09/16/26 – 09/23/26: From $609
    16

    We

  • PWM–MYR, 09/17/26 – 09/24/26: From $701
    17

    Th

  • PWM–MYR, 09/18/26 – 09/25/26: From $701
    18

    Fr

  • PWM–MYR, 09/19/26 – 09/26/26: From $609
    19

    Sa

  • PWM–MYR, 09/20/26 – 09/27/26: From $701
    20

    Su

  • PWM–MYR, 09/21/26 – 09/28/26: From $629
    21

    Mo

  • PWM–MYR, 09/22/26 – 09/29/26: From $583
    22

    Tu

  • PWM–MYR, 09/23/26 – 09/30/26: From $583
    23

    We

  • PWM–MYR, 09/24/26 – 10/01/26: From $719
    24

    Th

  • PWM–MYR, 09/25/26 – 10/02/26: From $629
    25

    Fr

  • PWM–MYR, 09/26/26 – 10/03/26: From $609
    26

    Sa

  • PWM–MYR, 09/27/26 – 10/04/26: From $701
    27

    Su

  • PWM–MYR, 09/28/26 – 10/05/26: From $579
    28

    Mo

  • PWM–MYR, 09/29/26 – 10/06/26: From $462
    29

    Tu

  • PWM–MYR, 09/30/26 – 10/07/26: From $462
    30

    We

  • PWM–MYR, 10/01/26 – 10/08/26: From $639
    01

    Th

    OCT

  • PWM–MYR, 10/02/26 – 10/09/26: From $495
    02

    Fr

  • PWM–MYR, 10/03/26 – 10/10/26: From $462
    03

    Sa

  • PWM–MYR, 10/04/26 – 10/11/26: From $675
    04

    Su

  • PWM–MYR, 10/05/26 – 10/12/26: From $568
    05

    Mo

  • PWM–MYR, 10/06/26 – 10/13/26: From $323
    06

    Tu

  • PWM–MYR, 10/07/26 – 10/14/26: From $427
    07

    We

  • PWM–MYR, 10/08/26 – 10/15/26: From $593
    08

    Th

  • PWM–MYR, 10/09/26 – 10/16/26: From $621
    09

    Fr

  • PWM–MYR, 10/10/26 – 10/17/26: From $550
    10

    Sa

  • PWM–MYR, 10/11/26 – 10/18/26: From $579
    11

    Su

  • PWM–MYR: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • PWM–MYR: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

  • PWM–MYR: cmp-view-offers-disclaimer. Find Offers
    14

    We

    • range$323-$719

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Portland, ME to Myrtle Beach flights

    $
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    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    Portland, ME (PWM)to

    Myrtle Beach (MYR)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $239Fare subject to changes
    Updated: 7 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Portland, ME to Myrtle Beach

    Looking for lower fares on your trip from Portland, ME to Myrtle Beach? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Portland, ME to Myrtle Beach