American Airlines flights from Detroit to Myrtle Beach

Recent searches for flights from Detroit to Myrtle Beach

Sep 2026
From$484*
Updated: 7 hours ago
Round tripIEconomy
Oct 2026
From$349*
Updated: 7 hours ago
Round tripIEconomy
Nov 2026
From$349*
Updated: 7 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $361
cmp-daily-histogram-bars-legend-max-price-aria-label $754
Displaying fares for September-2026
  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    10

    Th

    SEP

  • DTW–MYR, 09/11/26 – 09/18/26: From $754
    11

    Fr

  • DTW–MYR, 09/12/26 – 09/19/26: From $754
    12

    Sa

  • DTW–MYR, 09/13/26 – 09/20/26: From $754
    13

    Su

  • DTW–MYR, 09/14/26 – 09/21/26: From $754
    14

    Mo

  • DTW–MYR, 09/15/26 – 09/22/26: From $754
    15

    Tu

  • DTW–MYR, 09/16/26 – 09/23/26: From $749
    16

    We

  • DTW–MYR, 09/17/26 – 09/24/26: From $649
    17

    Th

  • DTW–MYR, 09/18/26 – 09/25/26: From $639
    18

    Fr

  • DTW–MYR, 09/19/26 – 09/26/26: From $639
    19

    Sa

  • DTW–MYR, 09/20/26 – 09/27/26: From $639
    20

    Su

  • DTW–MYR, 09/21/26 – 09/28/26: From $639
    21

    Mo

  • DTW–MYR, 09/22/26 – 09/29/26: From $639
    22

    Tu

  • DTW–MYR, 09/23/26 – 09/30/26: From $639
    23

    We

  • DTW–MYR, 09/24/26 – 10/01/26: From $499
    24

    Th

  • DTW–MYR, 09/25/26 – 10/02/26: From $499
    25

    Fr

  • DTW–MYR, 09/26/26 – 10/03/26: From $484
    26

    Sa

  • DTW–MYR, 09/27/26 – 10/04/26: From $639
    27

    Su

  • DTW–MYR, 09/28/26 – 10/05/26: From $499
    28

    Mo

  • DTW–MYR, 09/29/26 – 10/06/26: From $484
    29

    Tu

  • DTW–MYR, 09/30/26 – 10/07/26: From $484
    30

    We

  • DTW–MYR, 10/01/26 – 10/08/26: From $641
    01

    Th

    OCT

  • DTW–MYR, 10/02/26 – 10/09/26: From $543
    02

    Fr

  • DTW–MYR, 10/03/26 – 10/10/26: From $404
    03

    Sa

  • DTW–MYR, 10/04/26 – 10/11/26: From $474
    04

    Su

  • DTW–MYR, 10/05/26 – 10/12/26: From $399
    05

    Mo

  • DTW–MYR, 10/06/26 – 10/13/26: From $361
    06

    Tu

  • DTW–MYR, 10/07/26 – 10/14/26: From $399
    07

    We

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    08

    Th

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    09

    Fr

    • range$361-$754

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Detroit to Myrtle Beach flights

    $
    keyboard_arrow_down

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/23/26 - 10/30/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    Detroit (DTW)to

    Myrtle Beach (MYR)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $349Fare subject to changes
    Updated: 7 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Detroit to Myrtle Beach

    Looking for lower fares on your trip from Detroit to Myrtle Beach? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Citi / AAdvantage credit card offer.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Detroit to Myrtle Beach