American Airlines flights from United States to Cayman Islands

Popular flights with American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights from United States to the Cayman Islands

Business class flights from United States to Cayman Islands

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Dallas (DFW)to

Grand Cayman (GCM)
12/13/25 - 12/18/25

Round trip

Business / First

from
$2,091Fare subject to changes
Updated: 10 hours ago

Miami (MIA)to

Grand Cayman (GCM)
10/25/25 - 10/29/25

Round trip

Business / First

from
$803Fare subject to changes
Updated: 9 hours ago

Charlotte (CLT)to

Grand Cayman (GCM)
12/14/25 - 12/21/25

Round trip

Business / First

from
$1,396Fare subject to changes
Updated: 7 hours ago

Philadelphia (PHL)to

Grand Cayman (GCM)
02/02/26 - 02/08/26

Round trip

Business / First

from
$1,815Fare subject to changes
Updated: 1 hour ago

Boston (BOS)to

Grand Cayman (GCM)
01/17/26 - 01/24/26

Round trip

Business / First

from
$1,344Fare subject to changes
Updated: 3 hours ago

Chicago (ORD)to

Grand Cayman (GCM)
10/29/25 - 11/05/25

Round trip

Business / First

from
$1,012Fare subject to changes
Updated: 35 minutes ago

Hartford (BDL)to

Grand Cayman (GCM)
02/01/26 - 02/08/26

Round trip

Business / First

from
$1,188Fare subject to changes
Updated: 6 hours ago

Tampa (TPA)to

Grand Cayman (GCM)
12/20/25 - 12/24/25

Round trip

Business / First

from
$2,049Fare subject to changes
Updated: 2 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on United States to Cayman Islands flights

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Dallas (DFW)to

Grand Cayman (GCM)
12/16/25 - 12/23/25

Round trip

Economy

from
$502Fare subject to changes
Updated: 8 hours ago

Miami (MIA)to

Grand Cayman (GCM)
12/04/25 - 12/11/25

Round trip

Economy

from
$311Fare subject to changes
Updated: 14 hours ago

Charlotte (CLT)to

Grand Cayman (GCM)
11/18/25 - 11/25/25

Round trip

Economy

from
$330Fare subject to changes
Updated: 7 hours ago

Philadelphia (PHL)to

Grand Cayman (GCM)
02/03/26 - 02/10/26

Round trip

Economy

from
$520Fare subject to changes
Updated: 8 hours ago

Boston (BOS)to

Grand Cayman (GCM)
11/13/25 - 11/20/25

Round trip

Economy

from
$280Fare subject to changes
Updated: 5 hours ago

Salt Lake City (SLC)to

Grand Cayman (GCM)
02/03/26 - 02/10/26

Round trip

Economy

from
$625Fare subject to changes
Updated: 6 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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Top United States to Cayman Islands routes