
American Airlines flights from United States to Cayman Islands
expand_more
1 Adult, Economy class
expand_moreexpand_more
today
today
Popular flights with American Airlines
flight_takeoff
flight_land
$
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Business class flights from United States to Cayman Islands
flight_takeoff
flight_land
$
Dallas (DFW)to
Grand Cayman (GCM)
12/13/25 - 12/18/25
Round trip
Business / First
from
$2,091Fare subject to changes
Updated: 10 hours ago
Miami (MIA)to
Grand Cayman (GCM)
10/25/25 - 10/29/25
Round trip
Business / First
from
$803Fare subject to changes
Updated: 9 hours ago
Charlotte (CLT)to
Grand Cayman (GCM)
12/14/25 - 12/21/25
Round trip
Business / First
from
$1,396Fare subject to changes
Updated: 7 hours ago
Philadelphia (PHL)to
Grand Cayman (GCM)
02/02/26 - 02/08/26
Round trip
Business / First
from
$1,815Fare subject to changes
Updated: 1 hour ago
Boston (BOS)to
Grand Cayman (GCM)
01/17/26 - 01/24/26
Round trip
Business / First
from
$1,344Fare subject to changes
Updated: 3 hours ago
Chicago (ORD)to
Grand Cayman (GCM)
10/29/25 - 11/05/25
Round trip
Business / First
from
$1,012Fare subject to changes
Updated: 35 minutes ago
Hartford (BDL)to
Grand Cayman (GCM)
02/01/26 - 02/08/26
Round trip
Business / First
from
$1,188Fare subject to changes
Updated: 6 hours ago
Tampa (TPA)to
Grand Cayman (GCM)
12/20/25 - 12/24/25
Round trip
Business / First
from
$2,049Fare subject to changes
Updated: 2 hours ago
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
Find deals on United States to Cayman Islands flights
flight_takeoff
flight_land
$
Dallas (DFW)to
Grand Cayman (GCM)
12/16/25 - 12/23/25
Round trip
Economy
from
$502Fare subject to changes
Updated: 8 hours ago
Miami (MIA)to
Grand Cayman (GCM)
12/04/25 - 12/11/25
Round trip
Economy
from
$311Fare subject to changes
Updated: 14 hours ago
Charlotte (CLT)to
Grand Cayman (GCM)
11/18/25 - 11/25/25
Round trip
Economy
from
$330Fare subject to changes
Updated: 7 hours ago
Philadelphia (PHL)to
Grand Cayman (GCM)
02/03/26 - 02/10/26
Round trip
Economy
from
$520Fare subject to changes
Updated: 8 hours ago
Boston (BOS)to
Grand Cayman (GCM)
11/13/25 - 11/20/25
Round trip
Economy
from
$280Fare subject to changes
Updated: 5 hours ago
Salt Lake City (SLC)to
Grand Cayman (GCM)
02/03/26 - 02/10/26
Round trip
Economy
from
$625Fare subject to changes
Updated: 6 hours ago
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.