American Airlines flights from United States to Panama

Popular flights with American Airlines

$
keyboard_arrow_down

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights from United States to Panama

Business class flights from United States to Panama

$

Miami (MIA)to

Panama City (PTY)
12/03/25 - 12/10/25

Round trip

Business / First

from
$845Fare subject to changes
Updated: 4 hours ago

Dallas (DFW)to

Panama City (PTY)
01/02/26 - 01/09/26

Round trip

Business / First

from
$1,346Fare subject to changes
Updated: 5 hours ago

Charlotte (CLT)to

Panama City (PTY)
11/02/25 - 11/07/25

Round trip

Business / First

from
$878Fare subject to changes
Updated: 5 hours ago

Nashville (BNA)to

Panama City (PTY)
01/01/26 - 01/12/26

Round trip

Business / First

from
$1,041Fare subject to changes
Updated: 2 hours ago

Raleigh (RDU)to

Panama City (PTY)
01/10/26 - 01/17/26

Round trip

Business / First

from
$1,274Fare subject to changes
Updated: 1 hour ago

Philadelphia (PHL)to

Panama City (PTY)
01/24/26 - 01/29/26

Round trip

Business / First

from
$1,075Fare subject to changes
Updated: 45 minutes ago

New York (NYC)to

Panama City (PTY)
12/14/25 - 12/18/25

Round trip

Business / First

from
$1,458Fare subject to changes
Updated: 1 hour ago

Boston (BOS)to

Panama City (PTY)
11/28/25 - 12/01/25

Round trip

Business / First

from
$1,434Fare subject to changes
Updated: 16 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on United States to Panama flights

$
keyboard_arrow_down

Miami (MIA)to

Panama City (PTY)
12/08/25 - 12/15/25

Round trip

Economy

from
$276Fare subject to changes
Updated: 3 hours ago

Dallas (DFW)to

Panama City (PTY)
12/16/25 - 12/23/25

Round trip

Economy

from
$426Fare subject to changes
Updated: 6 hours ago

Charlotte (CLT)to

Panama City (PTY)
01/27/26 - 02/03/26

Round trip

Economy

from
$400Fare subject to changes
Updated: 4 hours ago

Los Angeles (LAX)to

Panama City (PTY)
01/08/26 - 01/15/26

Round trip

Economy

from
$613Fare subject to changes
Updated: 6 hours ago

Nashville (BNA)to

Panama City (PTY)
02/03/26 - 02/10/26

Round trip

Economy

from
$342Fare subject to changes
Updated: 4 hours ago

New York (NYC)to

Panama City (PTY)
01/08/26 - 01/15/26

Round trip

Economy

from
$562Fare subject to changes
Updated: 2 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Earn up to $250 back on your next American Airlines flight plus, 40,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

Top United States to Panama routes