American Airlines flights from United States to Panama

Popular flights with American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights from the United States to Panama

Business class flights from United States to Panama

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Miami (MIA)to

Panama City (PTY)
03/15/26 - 03/26/26

Round trip

Business / First

from
$1,207Fare subject to changes
Updated: 15 hours ago

Dallas (DFW)to

Panama City (PTY)
04/29/26 - 05/13/26

Round trip

Business / First

from
$1,214Fare subject to changes
Updated: 4 hours ago

Charlotte (CLT)to

Panama City (PTY)
03/07/26 - 03/13/26

Round trip

Business / First

from
$1,583Fare subject to changes
Updated: 7 minutes ago

New York (JFK)to

Panama City (PTY)
04/02/26 - 04/08/26

Round trip

Business / First

from
$1,123Fare subject to changes
Updated: 15 hours ago

Baltimore (BWI)to

Panama City (PTY)
03/23/26 - 03/29/26

Round trip

Business / First

from
$1,484Fare subject to changes
Updated: 14 hours ago

Washington, D.C. (DCA)to

Panama City (PTY)
02/09/26 - 02/18/26

Round trip

Business / First

from
$3,168Fare subject to changes
Updated: 2 hours ago

New York/Newark (EWR)to

Panama City (PTY)
02/27/26 - 03/01/26

Round trip

Business / First

from
$1,462Fare subject to changes
Updated: 3 minutes ago

New York (NYC)to

Panama City (PTY)
03/15/26 - 03/26/26

Round trip

Business / First

from
$1,434Fare subject to changes
Updated: 17 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on United States to Panama flights

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Miami (MIA)to

Panama City (PTY)
03/15/26 - 03/26/26

Round trip

Economy

from
$400Fare subject to changes
Updated: 15 hours ago

Dallas (DFW)to

Panama City (PTY)
04/29/26 - 05/13/26

Round trip

Economy

from
$521Fare subject to changes
Updated: 4 hours ago

Charlotte (CLT)to

Panama City (PTY)
05/19/26 - 05/26/26

Round trip

Economy

from
$489Fare subject to changes
Updated: 15 hours ago

Raleigh (RDU)to

Panama City (PTY)
05/29/26 - 06/05/26

Round trip

Economy

from
$581Fare subject to changes
Updated: 53 minutes ago

Nashville (BNA)to

Panama City (PTY)
06/11/26 - 06/18/26

Round trip

Economy

from
$519Fare subject to changes
Updated: 2 hours ago

New York (JFK)to

Panama City (PTY)
04/02/26 - 04/08/26

Round trip

Economy

from
$608Fare subject to changes
Updated: 15 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Earn up to $250 back on your next American Airlines flight plus, 40,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

Top United States to Panama routes