American Airlines flights from United States to Panama

Popular flights with American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights from United States to Panama

Business class flights from United States to Panama

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Miami (MIA)to

Panama City (PTY)
01/22/26 - 01/25/26

Round trip

Business / First

from
$1,191Fare subject to changes
Updated: 17 hours ago

Dallas (DFW)to

Panama City (PTY)
01/03/26 - 01/10/26

Round trip

Business / First

from
$1,373Fare subject to changes
Updated: 17 hours ago

Philadelphia (PHL)to

Panama City (PTY)
12/13/25 - 12/17/25

Round trip

Business / First

from
$1,350Fare subject to changes
Updated: 14 hours ago

Atlanta (ATL)to

Panama City (PTY)
01/12/26 - 01/17/26

Round trip

Business / First

from
$1,304Fare subject to changes
Updated: 6 hours ago

Phoenix (PHX)to

Panama City (PTY)
12/26/25 - 12/29/25

Round trip

Business / First

from
$2,378Fare subject to changes
Updated: 13 hours ago

Washington, D.C. (WAS)to

Panama City (PTY)
12/13/25 - 01/05/26

Round trip

Business / First

from
$1,728Fare subject to changes
Updated: 12 hours ago

Jacksonville (JAX)to

Panama City (PTY)
01/31/26 - 02/10/26

Round trip

Business / First

from
$1,613Fare subject to changes
Updated: 17 hours ago

Saint Louis (STL)to

Panama City (PTY)
12/29/25 - 01/08/26

Round trip

Business / First

from
$1,642Fare subject to changes
Updated: 14 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on United States to Panama flights

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Miami (MIA)to

Panama City (PTY)
12/08/25 - 12/12/25

Round trip

Economy

from
$276Fare subject to changes
Updated: 14 hours ago

Dallas (DFW)to

Panama City (PTY)
02/03/26 - 02/10/26

Round trip

Economy

from
$426Fare subject to changes
Updated: 15 hours ago

Denver (DEN)to

Panama City (PTY)
01/17/26 - 01/24/26

Round trip

Economy

from
$550Fare subject to changes
Updated: 14 hours ago

Charlotte (CLT)to

Panama City (PTY)
11/18/25 - 11/25/25

Round trip

Economy

from
$400Fare subject to changes
Updated: 6 hours ago

Philadelphia (PHL)to

Panama City (PTY)
12/13/25 - 12/17/25

Round trip

Economy

from
$496Fare subject to changes
Updated: 14 hours ago

Indianapolis (IND)to

Panama City (PTY)
01/21/26 - 01/28/26

Round trip

Economy

from
$490Fare subject to changes
Updated: 4 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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Top United States to Panama routes