American Airlines flights from United States to Panama

Popular flights with American Airlines

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*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

American Airlines flights from United States to Panama

Business class flights from United States to Panama

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Miami (MIA)to

Panama City (PTY)
12/13/25 - 12/17/25

Round trip

Business / First

from
$1,054Fare subject to changes
Updated: 8 hours ago

Dallas (DFW)to

Panama City (PTY)
03/06/26 - 03/10/26

Round trip

Business / First

from
$1,448Fare subject to changes
Updated: 8 hours ago

Seattle (SEA)to

Panama City (PTY)
01/19/26 - 01/26/26

Round trip

Business / First

from
$2,257Fare subject to changes
Updated: 16 hours ago

Philadelphia (PHL)to

Panama City (PTY)
01/03/26 - 01/09/26

Round trip

Business / First

from
$960Fare subject to changes
Updated: 8 hours ago

Raleigh (RDU)to

Panama City (PTY)
02/20/26 - 02/28/26

Round trip

Business / First

from
$1,298Fare subject to changes
Updated: 8 hours ago

Charlotte (CLT)to

Panama City (PTY)
03/11/26 - 03/15/26

Round trip

Business / First

from
$1,445Fare subject to changes
Updated: 12 hours ago

Chicago (ORD)to

Panama City (PTY)
03/16/26 - 03/21/26

Round trip

Business / First

from
$1,250Fare subject to changes
Updated: 12 hours ago

Tampa (TPA)to

Panama City (PTY)
03/05/26 - 03/14/26

Round trip

Business / First

from
$1,278Fare subject to changes
Updated: 7 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Find deals on United States to Panama flights

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Miami (MIA)to

Panama City (PTY)
02/01/26 - 02/05/26

Round trip

Economy

from
$317Fare subject to changes
Updated: 4 hours ago

Dallas (DFW)to

Panama City (PTY)
04/28/26 - 05/05/26

Round trip

Economy

from
$500Fare subject to changes
Updated: 16 hours ago

Seattle (SEA)to

Panama City (PTY)
01/19/26 - 01/26/26

Round trip

Economy

from
$660Fare subject to changes
Updated: 16 hours ago

Philadelphia (PHL)to

Panama City (PTY)
04/16/26 - 04/23/26

Round trip

Economy

from
$500Fare subject to changes
Updated: 4 hours ago

Raleigh (RDU)to

Panama City (PTY)
02/20/26 - 02/28/26

Round trip

Economy

from
$460Fare subject to changes
Updated: 8 hours ago

Charlotte (CLT)to

Panama City (PTY)
03/11/26 - 03/15/26

Round trip

Economy

from
$567Fare subject to changes
Updated: 12 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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Top United States to Panama routes