American Airlines flights from Destin to Portland, OR

Recent searches for flights from Destin to Portland, OR

Sep 2026
From$409*
Updated: 17 hours ago
Round tripIEconomy
Oct 2026
From$379*
Updated: 17 hours ago
Round tripIEconomy
Nov 2026
From$379*
Updated: 17 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $409
cmp-daily-histogram-bars-legend-max-price-aria-label $949
Displaying fares for September-2026
  • VPS–PDX: cmp-view-offers-disclaimer. Find Offers
    04

    Fr

    SEP

  • VPS–PDX, 09/05/26 – 09/12/26: From $533
    05

    Sa

  • VPS–PDX, 09/06/26 – 09/13/26: From $695
    06

    Su

  • VPS–PDX, 09/07/26 – 09/14/26: From $949
    07

    Mo

  • VPS–PDX, 09/08/26 – 09/15/26: From $881
    08

    Tu

  • VPS–PDX, 09/09/26 – 09/16/26: From $533
    09

    We

  • VPS–PDX, 09/10/26 – 09/17/26: From $695
    10

    Th

  • VPS–PDX, 09/11/26 – 09/18/26: From $665
    11

    Fr

  • VPS–PDX, 09/12/26 – 09/19/26: From $533
    12

    Sa

  • VPS–PDX, 09/13/26 – 09/20/26: From $711
    13

    Su

  • VPS–PDX, 09/14/26 – 09/21/26: From $665
    14

    Mo

  • VPS–PDX, 09/15/26 – 09/22/26: From $533
    15

    Tu

  • VPS–PDX, 09/16/26 – 09/23/26: From $533
    16

    We

  • VPS–PDX, 09/17/26 – 09/24/26: From $665
    17

    Th

  • VPS–PDX, 09/18/26 – 09/25/26: From $592
    18

    Fr

  • VPS–PDX, 09/19/26 – 09/26/26: From $492
    19

    Sa

  • VPS–PDX, 09/20/26 – 09/27/26: From $852
    20

    Su

  • VPS–PDX, 09/21/26 – 09/28/26: From $537
    21

    Mo

  • VPS–PDX, 09/22/26 – 09/29/26: From $486
    22

    Tu

  • VPS–PDX, 09/23/26 – 09/30/26: From $533
    23

    We

  • VPS–PDX, 09/24/26 – 10/01/26: From $610
    24

    Th

  • VPS–PDX, 09/25/26 – 10/02/26: From $494
    25

    Fr

  • VPS–PDX, 09/26/26 – 10/03/26: From $486
    26

    Sa

  • VPS–PDX, 09/27/26 – 10/04/26: From $577
    27

    Su

  • VPS–PDX, 09/28/26 – 10/05/26: From $556
    28

    Mo

  • VPS–PDX, 09/29/26 – 10/06/26: From $409
    29

    Tu

  • VPS–PDX, 09/30/26 – 10/07/26: From $439
    30

    We

  • VPS–PDX, 10/01/26 – 10/08/26: From $613
    01

    Th

    OCT

  • VPS–PDX: cmp-view-offers-disclaimer. Find Offers
    02

    Fr

  • VPS–PDX: cmp-view-offers-disclaimer. Find Offers
    03

    Sa

    • range$409-$949

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Destin to Portland, OR flights

    $
    keyboard_arrow_down

    Destin (VPS)to

    Portland, OR (PDX)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    Destin (VPS)to

    Portland, OR (PDX)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    Destin (VPS)to

    Portland, OR (PDX)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    Destin (VPS)to

    Portland, OR (PDX)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    Destin (VPS)to

    Portland, OR (PDX)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    Destin (VPS)to

    Portland, OR (PDX)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    Destin (VPS)to

    Portland, OR (PDX)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    Destin (VPS)to

    Portland, OR (PDX)
    11/11/26 - 11/18/26

    Round trip

    Economy

    from
    $379Fare subject to changes
    Updated: 17 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Destin to Portland, OR

    Looking for lower fares on your trip from Destin to Portland, OR? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Citi / AAdvantage credit card offer.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Destin to Portland, OR