Great Deals on Flights to South America
Home  ›  American Airlines flights  › Flights to South America
                          Â
Experience the most amazing South America destinations while enjoying premier services offered by American Airlines with our flights to Brazil, Argentina, Colombia, Chile, Peru, and More!
From | To | Fare type | Travel dates | Price |
|---|---|---|---|---|
| Miami (MIA) | Sao Paulo (GRU) | Round trip I Economy | 03/10/26 - 03/16/26 | from $535Fare subject to changes Updated: 9 minutes ago |
| Dallas (DFW) | Sao Paulo (GRU) | Round trip I Economy | 09/24/25 - 10/02/25 | from $1,536Fare subject to changes Updated: 17 hours ago |
| New York (JFK) | Sao Paulo (GRU) | Round trip I Economy | 09/23/25 - 09/30/25 | from $825Fare subject to changes Updated: 16 hours ago |
| Orlando (MCO) | Sao Paulo (GRU) | Round trip I Economy | 11/06/25 - 11/17/25 | from $450Fare subject to changes Updated: 17 hours ago |
| Boston (BOS) | Sao Paulo (GRU) | Round trip I Economy | 10/03/25 - 10/12/25 | from $580Fare subject to changes Updated: 15 hours ago |
| Miami (MIA) | Sao Paulo (SAO) | Round trip I Economy | 03/10/26 - 03/13/26 | from $535Fare subject to changes Updated: 21 hours ago |
| San Francisco (SFO) | Sao Paulo (GRU) | Round trip I Economy | 10/29/25 - 11/12/25 | from $650Fare subject to changes Updated: 9 hours ago |
| New York (NYC) | Sao Paulo (GRU) | Round trip I Economy | 10/13/25 - 10/22/25 | from $665Fare subject to changes Updated: 9 hours ago |
| Charlotte (CLT) | Sao Paulo (GRU) | Round trip I Economy | 11/06/25 - 12/04/25 | from $1,240Fare subject to changes Updated: 15 hours ago |
| Philadelphia (PHL) | Sao Paulo (GRU) | Round trip I Economy | 01/15/26 - 01/20/26 | from $1,045Fare subject to changes Updated: 21 minutes ago |
| Phoenix (PHX) | Sao Paulo (GRU) | Round trip I Economy | 11/09/25 - 11/14/25 | from $1,138Fare subject to changes Updated: 17 hours ago |
| Austin (AUS) | Sao Paulo (GRU) | Round trip I Economy | 05/11/26 - 05/25/26 | from $505Fare subject to changes Updated: 10 hours ago |
| Denver (DEN) | Sao Paulo (GRU) | Round trip I Economy | 12/12/25 - 01/12/26 | from $1,285Fare subject to changes Updated: 16 hours ago |
| Chicago (ORD) | Sao Paulo (GRU) | Round trip I Economy | 10/03/25 - 10/20/25 | from $500Fare subject to changes Updated: 23 hours ago |
| San Diego (SAN) | Sao Paulo (GRU) | Round trip I Economy | 12/26/25 - 01/12/26 | from $1,162Fare subject to changes Updated: 2 hours ago |
| Miami (MIA) | Sao Paulo (GRU) | Round trip I Economy | 12/01/25 - 01/29/26 | from $535Fare subject to changes Updated: 22 hours ago |
| Miami (MIA) | Rio de Janeiro (GIG) | Round trip I Economy | 10/15/25 - 10/22/25 | from $818Fare subject to changes Updated: 21 hours ago |
| Dallas (DFW) | Sao Paulo (GRU) | Round trip I Economy | 09/24/25 - 10/02/25 | from $1,536Fare subject to changes Updated: 17 hours ago |
| New York (JFK) | Sao Paulo (GRU) | Round trip I Economy | 01/09/26 - 01/26/26 | from $825Fare subject to changes Updated: 19 hours ago |
| Orlando (MCO) | Sao Paulo (GRU) | Round trip I Economy | 11/06/25 - 11/17/25 | from $450Fare subject to changes Updated: 17 hours ago |
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
From | To | Fare type | Travel dates | Price |
|---|---|---|---|---|
| Miami (MIA) | Mendoza (MDZ) | Round trip I Economy | 05/31/26 - 06/08/26 | from $1,491Fare subject to changes Updated: 22 hours ago |
| Miami (MIA) | Buenos Aires (EZE) | Round trip I Economy | 11/25/25 - 12/01/25 | from $751Fare subject to changes Updated: 2 hours ago |
| New York (JFK) | Buenos Aires (EZE) | Round trip I Economy | 03/30/26 - 04/15/26 | from $921Fare subject to changes Updated: 14 hours ago |
| Dallas (DFW) | Buenos Aires (EZE) | Round trip I Economy | 02/28/26 - 03/09/26 | from $1,111Fare subject to changes Updated: 21 hours ago |
| New York (NYC) | Buenos Aires (EZE) | Round trip I Economy | 02/10/26 - 02/17/26 | from $935Fare subject to changes Updated: 6 hours ago |
| Los Angeles (LAX) | Buenos Aires (EZE) | Round trip I Economy | 11/03/25 - 11/09/25 | from $757Fare subject to changes Updated: 16 hours ago |
| Chicago (ORD) | Buenos Aires (EZE) | Round trip I Economy | 03/20/26 - 03/27/26 | from $1,348Fare subject to changes Updated: 11 hours ago |
| San Francisco (SFO) | Buenos Aires (EZE) | Round trip I Economy | 01/27/26 - 02/24/26 | from $1,025Fare subject to changes Updated: 52 minutes ago |
| Austin (AUS) | Buenos Aires (EZE) | Round trip I Economy | 10/03/25 - 10/11/25 | from $622Fare subject to changes Updated: 14 hours ago |
| Boston (BOS) | Buenos Aires (EZE) | Round trip I Economy | 12/01/25 - 12/14/25 | from $1,095Fare subject to changes Updated: 23 hours ago |
| Orlando (MCO) | Buenos Aires (EZE) | Round trip I Economy | 10/06/25 - 10/20/25 | from $767Fare subject to changes Updated: 21 hours ago |
| Tampa (TPA) | Buenos Aires (EZE) | Round trip I Economy | 10/21/25 - 10/28/25 | from $609Fare subject to changes Updated: 20 hours ago |
| Denver (DEN) | Buenos Aires (EZE) | Round trip I Economy | 05/01/26 - 05/16/26 | from $1,105Fare subject to changes Updated: 21 hours ago |
| Washington, D.C. (DCA) | Buenos Aires (EZE) | Round trip I Economy | 10/29/25 - 11/04/25 | from $689Fare subject to changes Updated: 23 hours ago |
| Phoenix (PHX) | Buenos Aires (EZE) | Round trip I Economy | 01/27/26 - 02/24/26 | from $1,155Fare subject to changes Updated: 53 minutes ago |
| San Diego (SAN) | Buenos Aires (EZE) | Round trip I Economy | 01/16/26 - 01/26/26 | from $1,065Fare subject to changes Updated: 12 hours ago |
| Las Vegas (LAS) | Buenos Aires (EZE) | Round trip I Economy | 12/24/25 - 01/07/26 | from $1,046Fare subject to changes Updated: 22 hours ago |
| Houston (IAH) | Buenos Aires (EZE) | Round trip I Economy | 02/26/26 - 03/14/26 | from $1,495Fare subject to changes Updated: 19 hours ago |
| Philadelphia (PHL) | Buenos Aires (EZE) | Round trip I Economy | 11/30/25 - 12/07/25 | from $1,605Fare subject to changes Updated: 4 hours ago |
| Seattle (SEA) | Buenos Aires (EZE) | Round trip I Economy | 03/10/26 - 03/24/26 | from $1,175Fare subject to changes Updated: 19 hours ago |
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
From | To | Fare type | Travel dates | Price |
|---|---|---|---|---|
| Miami (MIA) | Medellin (MDE) | Round trip I Economy | 10/31/25 - 11/14/25 | from $268Fare subject to changes Updated: 12 hours ago |
| Miami (MIA) | Medellin (MDE) | Round trip I Economy | 11/07/25 - 11/11/25 | from $268Fare subject to changes Updated: 14 hours ago |
| Miami (MIA) | Bogota (BOG) | Round trip I Economy | 11/15/25 - 11/22/25 | from $238Fare subject to changes Updated: 12 hours ago |
| Miami (MIA) | Bogota (BOG) | Round trip I Economy | 11/02/25 - 11/07/25 | from $238Fare subject to changes Updated: 7 hours ago |
| Miami (MIA) | Cartagena (CTG) | Round trip I Economy | 11/28/25 - 12/02/25 | from $535Fare subject to changes Updated: 17 hours ago |
| Miami (MIA) | Cartagena (CTG) | Round trip I Economy | 12/05/25 - 01/30/26 | from $411Fare subject to changes Updated: 40 minutes ago |
| Miami (MIA) | Cali (CLO) | Round trip I Economy | 10/09/25 - 10/21/25 | from $386Fare subject to changes Updated: 17 hours ago |
| Miami (MIA) | Cali (CLO) | Round trip I Economy | 10/25/25 - 11/08/25 | from $388Fare subject to changes Updated: 12 hours ago |
| Miami (MIA) | Barranquilla (BAQ) | Round trip I Economy | 09/19/25 - 09/21/25 | from $481Fare subject to changes Updated: 3 hours ago |
| Miami (MIA) | Barranquilla (BAQ) | Round trip I Economy | 01/18/26 - 01/25/26 | from $560Fare subject to changes Updated: 15 hours ago |
| Dallas (DFW) | Bogota (BOG) | Round trip I Economy | 11/27/25 - 12/03/25 | from $528Fare subject to changes Updated: 1 minute ago |
| Dallas (DFW) | Bogota (BOG) | Round trip I Economy | 09/26/25 - 10/25/25 | from $534Fare subject to changes Updated: 16 hours ago |
| Dallas (DFW) | Medellin (MDE) | Round trip I Economy | 12/09/25 - 12/14/25 | from $523Fare subject to changes Updated: 16 hours ago |
| Dallas (DFW) | Medellin (MDE) | Round trip I Economy | 11/14/25 - 11/17/25 | from $553Fare subject to changes Updated: 17 hours ago |
| San Francisco (SFO) | Bogota (BOG) | Round trip I Economy | 12/15/25 - 01/15/26 | from $630Fare subject to changes Updated: 16 hours ago |
| San Francisco (SFO) | Bogota (BOG) | Round trip I Economy | 12/15/25 - 01/02/26 | from $920Fare subject to changes Updated: 16 hours ago |
| Tampa (TPA) | Medellin (MDE) | Round trip I Economy | 12/23/25 - 02/23/26 | from $597Fare subject to changes Updated: 13 hours ago |
| Tampa (TPA) | Medellin (MDE) | Round trip I Economy | 12/19/25 - 02/19/26 | from $657Fare subject to changes Updated: 13 hours ago |
| Charlotte (CLT) | Bogota (BOG) | Round trip I Economy | 12/21/25 - 01/01/26 | from $698Fare subject to changes Updated: 14 hours ago |
| Boston (BOS) | Medellin (MDE) | Round trip I Economy | 10/01/25 - 10/15/25 | from $431Fare subject to changes Updated: 13 hours ago |
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.
From | To | Fare type | Travel dates | Price |
|---|---|---|---|---|
| Miami (MIA) | Santiago (SCL) | Round trip I Economy | 11/03/25 - 12/08/25 | from $575Fare subject to changes Updated: 21 hours ago |
| Miami (MIA) | Santiago (SCL) | Round trip I Economy | 10/29/25 - 11/11/25 | from $575Fare subject to changes Updated: 21 hours ago |
| Dallas (DFW) | Santiago (SCL) | Round trip I Economy | 01/26/26 - 02/17/26 | from $599Fare subject to changes Updated: 19 hours ago |
| Dallas (DFW) | Santiago (SCL) | Round trip I Economy | 10/22/25 - 10/29/25 | from $614Fare subject to changes Updated: 22 hours ago |
| San Francisco (SFO) | Santiago (SCL) | Round trip I Economy | 09/27/25 - 10/05/25 | from $578Fare subject to changes Updated: 3 hours ago |
| San Francisco (SFO) | Santiago (SCL) | Round trip I Economy | 11/20/25 - 12/05/25 | from $588Fare subject to changes Updated: 18 hours ago |
| Chicago (ORD) | Santiago (SCL) | Round trip I Economy | 10/19/25 - 11/12/25 | from $804Fare subject to changes Updated: 22 hours ago |
| Chicago (ORD) | Santiago (SCL) | Round trip I Economy | 10/18/25 - 11/12/25 | from $815Fare subject to changes Updated: 23 hours ago |
| Denver (DEN) | Santiago (SCL) | Round trip I Economy | 09/27/25 - 10/06/25 | from $893Fare subject to changes Updated: 23 hours ago |
| Charlotte (CLT) | Santiago (SCL) | Round trip I Economy | 11/19/25 - 12/03/25 | from $714Fare subject to changes Updated: 58 minutes ago |
| Charlotte (CLT) | Santiago (SCL) | Round trip I Economy | 09/30/25 - 10/17/25 | from $813Fare subject to changes Updated: 1 hour ago |
| Orlando (MCO) | Santiago (SCL) | Round trip I Economy | 12/19/25 - 01/02/26 | from $1,385Fare subject to changes Updated: 1 hour ago |
| Tampa (TPA) | Santiago (SCL) | Round trip I Economy | 12/23/25 - 01/11/26 | from $934Fare subject to changes Updated: 11 hours ago |
| Seattle (SEA) | Santiago (SCL) | Round trip I Economy | 11/09/25 - 02/09/26 | from $1,018Fare subject to changes Updated: 21 hours ago |
| Seattle (SEA) | Santiago (SCL) | Round trip I Economy | 02/09/26 - 03/13/26 | from $1,064Fare subject to changes Updated: 21 hours ago |
| Milwaukee (MKE) | Santiago (SCL) | Round trip I Economy | 10/24/25 - 10/31/25 | from $848Fare subject to changes Updated: 1 hour ago |
| Houston (IAH) | Santiago (SCL) | Round trip I Economy | 09/29/25 - 10/13/25 | from $1,639Fare subject to changes Updated: 11 hours ago |
| Miami (MIA) | Santiago (SCL) | Round trip I Economy | 11/03/25 - 12/08/25 | from $575Fare subject to changes Updated: 21 hours ago |
| Miami (MIA) | Santiago (SCL) | Round trip I Economy | 10/29/25 - 11/11/25 | from $575Fare subject to changes Updated: 21 hours ago |
| Dallas (DFW) | Santiago (SCL) | Round trip I Economy | 01/26/26 - 02/17/26 | from $599Fare subject to changes Updated: 19 hours ago |
From | To | Fare type | Travel dates | Price |
|---|---|---|---|---|
| Miami (MIA) | Lima (LIM) | Round trip I Economy | 10/20/25 - 10/30/25 | from $440Fare subject to changes Updated: 12 hours ago |
| Dallas (DFW) | Lima (LIM) | Round trip I Economy | 05/25/26 - 05/31/26 | from $686Fare subject to changes Updated: 19 hours ago |
| Chicago (ORD) | Lima (LIM) | Round trip I Economy | 10/16/25 - 10/27/25 | from $515Fare subject to changes Updated: 12 hours ago |
| Tampa (TPA) | Lima (LIM) | Round trip I Economy | 09/26/25 - 09/28/25 | from $415Fare subject to changes Updated: 22 hours ago |
| Los Angeles (LAX) | Lima (LIM) | Round trip I Economy | 02/23/26 - 03/11/26 | from $664Fare subject to changes Updated: 16 hours ago |
| Washington, D.C. (DCA) | Lima (LIM) | Round trip I Economy | 11/01/25 - 11/17/25 | from $401Fare subject to changes Updated: 23 hours ago |
| Orlando (MCO) | Lima (LIM) | Round trip I Economy | 09/14/25 - 09/17/25 | from $513Fare subject to changes Updated: 21 hours ago |
| Charlotte (CLT) | Lima (LIM) | Round trip I Economy | 04/05/26 - 04/10/26 | from $715Fare subject to changes Updated: 23 hours ago |
| San Francisco (SFO) | Lima (LIM) | Round trip I Economy | 12/16/25 - 01/07/26 | from $898Fare subject to changes Updated: 11 hours ago |
| Austin (AUS) | Lima (LIM) | Round trip I Economy | 10/17/25 - 10/22/25 | from $389Fare subject to changes Updated: 3 hours ago |
| New York (NYC) | Lima (LIM) | Round trip I Economy | 12/20/25 - 01/05/26 | from $1,697Fare subject to changes Updated: 20 hours ago |
| New York/Newark (EWR) | Lima (LIM) | Round trip I Economy | 12/22/25 - 01/21/26 | from $1,010Fare subject to changes Updated: 28 minutes ago |
| New York (JFK) | Lima (LIM) | Round trip I Economy | 02/08/26 - 02/14/26 | from $540Fare subject to changes Updated: 22 hours ago |
| Boston (BOS) | Lima (LIM) | Round trip I Economy | 09/27/25 - 10/04/25 | from $599Fare subject to changes Updated: 20 hours ago |
| Denver (DEN) | Lima (LIM) | Round trip I Economy | 10/18/25 - 11/01/25 | from $535Fare subject to changes Updated: 22 hours ago |
| Los Angeles (LAX) | Cusco (CUZ) | Round trip I Economy | 11/15/25 - 11/22/25 | from $1,143Fare subject to changes Updated: 22 hours ago |
| Dallas (DFW) | Cusco (CUZ) | Round trip I Economy | 01/01/26 - 01/12/26 | from $952Fare subject to changes Updated: 12 hours ago |
| Miami (MIA) | Lima (LIM) | Round trip I Economy | 10/20/25 - 10/30/25 | from $440Fare subject to changes Updated: 12 hours ago |
| Dallas (DFW) | Lima (LIM) | Round trip I Economy | 05/25/26 - 05/31/26 | from $686Fare subject to changes Updated: 19 hours ago |
| Chicago (ORD) | Lima (LIM) | Round trip I Economy | 10/16/25 - 10/27/25 | from $515Fare subject to changes Updated: 12 hours ago |
*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.