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Visit Latin America with American Airlines

Looking to explore the vibrant cultures, breathtaking landscapes and unforgettable flavors of Latin America? American Airlines makes it easy to get there with cheap flights to top destinations in South America, Central America and the Caribbean.

Whether you're planning a beach escape in Costa Rica, a culinary adventure in Mexico City, or a bucket-list trip to Machu Picchu, we have the flight deals to get you there.

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Discover more of Latin America with JetSMART

Together with JetSMART, we offer affordable deals to even more destinations across South America.

Popular flights with JetSMART

USD

Nashville (BNA)to

Calama (CJC)
08/26/25 - 09/02/25

Round trip

Economy

from
USD990Fare subject to changes
Updated: 54 minutes ago

Boston (BOS)to

Calama (CJC)
09/01/25 - 09/08/25

Round trip

Economy

from
USD749Fare subject to changes
Updated: 11 hours ago

Austin (AUS)to

Puerto Montt (PMC)
10/25/25 - 11/01/25

Round trip

Economy

from
USD940Fare subject to changes
Updated: 5 hours ago

Boston (BOS)to

Puerto Montt (PMC)
10/02/25 - 10/09/25

Round trip

Economy

from
USD729Fare subject to changes
Updated: 5 hours ago

Houston (HOU)to

Antofagasta (ANF)
11/05/25 - 11/12/25

Round trip

Economy

from
USD1,254Fare subject to changes
Updated: 1 hour ago

Seattle (SEA)to

Antofagasta (ANF)
11/17/25 - 11/24/25

Round trip

Economy

from
USD1,364Fare subject to changes
Updated: 5 hours ago

Houston (HOU)to

Temuco (ZCO)
09/10/25 - 09/17/25

Round trip

Economy

from
USD1,397Fare subject to changes
Updated: 54 minutes ago

Nashville (BNA)to

Temuco (ZCO)
09/10/25 - 09/17/25

Round trip

Economy

from
USD1,020Fare subject to changes
Updated: 3 hours ago

New York (NYC)to

Iquique (IQQ)
11/18/25 - 11/25/25

Round trip

Economy

from
USD865Fare subject to changes
Updated: 3 hours ago

Charlotte (CLT)to

Iquique (IQQ)
09/02/25 - 09/09/25

Round trip

Economy

from
USD1,010Fare subject to changes
Updated: 54 minutes ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Popular round-trip flights to Latin America on American Airlines

Looking for cheap flights to Latin America? Our fare deals are updated regularly so you can find great prices for your next getaway. Whether you're flying for business, adventure or a family reunion, American Airlines helps you travel smart and save.

USD
Popular round-trip flights to Latin America on American Airlines
From
To
Fare type
Travel dates
Price
Miami (MIA)Montevideo (MVD)Round trip
I
Economy		12/03/25 - 12/08/25

from

USD752Fare subject to changes

Updated: 1 hour ago

Miami (MIA)Sao Paulo (GRU)Round trip
I
Economy		11/04/25 - 11/11/25

from

USD534Fare subject to changes

Updated: 9 hours ago

Miami (MIA)Buenos Aires (EZE)Round trip
I
Economy		10/20/25 - 10/27/25

from

USD841Fare subject to changes

Updated: 3 hours ago

Miami (MIA)Quito (UIO)Round trip
I
Economy		10/13/25 - 10/20/25

from

USD406Fare subject to changes

Updated: 15 minutes ago

Miami (MIA)Santiago (SCL)Round trip
I
Economy		11/04/25 - 11/11/25

from

USD563Fare subject to changes

Updated: 9 hours ago

Miami (MIA)Panama City (PTY)Round trip
I
Economy		10/03/25 - 10/10/25

from

USD349Fare subject to changes

Updated: 10 hours ago

Miami (MIA)Lima (LIM)Round trip
I
Economy		11/19/25 - 11/26/25

from

USD493Fare subject to changes

Updated: 9 hours ago

Miami (MIA)Managua (MGA)Round trip
I
Economy		08/07/25 - 08/14/25

from

USD248Fare subject to changes

Updated: 9 hours ago

*Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

Flying with American Airlines

American Airlines connects you more than 350 destinations in over 60 countries with thousands of daily flights. As a founding member of the oneworld® alliance, we offer access to a global network of more than 900 destinations. Along with our extensive network, we're committed to delivering a world-class experience through thoughtful service and premium spaces that customers can relax before their flight, including the Admirals Club® and Flagship® lounge.

As you explore more of the world, you can earn miles and unlock travel benefits through the AAdvantage® program, one of the most rewarding loyalty programs in the industry. Join the AAdvantage® program for free today.

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