American Airlines flights from Charleston, SC to Buffalo

Recent searches for flights from Charleston, SC to Buffalo

Aug 2026
From$262*
Updated: 10 hours ago
Round tripIEconomy
Sep 2026
From$197*
Updated: 10 hours ago
Round tripIEconomy
Oct 2026
From$197*
Updated: 10 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $197
cmp-daily-histogram-bars-legend-max-price-aria-label $652
Displaying fares for August-2026
  • CHS–BUF, 08/12/26 – 08/19/26: From $549
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    AUG

  • CHS–BUF, 08/13/26 – 08/20/26: From $623
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  • CHS–BUF, 08/14/26 – 08/21/26: From $623
    14

    Fr

  • CHS–BUF, 08/15/26 – 08/22/26: From $549
    15

    Sa

  • CHS–BUF, 08/16/26 – 08/23/26: From $652
    16

    Su

  • CHS–BUF, 08/17/26 – 08/24/26: From $652
    17

    Mo

  • CHS–BUF, 08/18/26 – 08/25/26: From $438
    18

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  • CHS–BUF, 08/19/26 – 08/26/26: From $438
    19

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  • CHS–BUF, 08/20/26 – 08/27/26: From $487
    20

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  • CHS–BUF, 08/21/26 – 08/28/26: From $487
    21

    Fr

  • CHS–BUF, 08/22/26 – 08/29/26: From $438
    22

    Sa

  • CHS–BUF, 08/23/26 – 08/30/26: From $487
    23

    Su

  • CHS–BUF, 08/24/26 – 08/31/26: From $410
    24

    Mo

  • CHS–BUF, 08/25/26 – 09/01/26: From $262
    25

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  • CHS–BUF, 08/26/26 – 09/02/26: From $262
    26

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  • CHS–BUF, 08/27/26 – 09/03/26: From $337
    27

    Th

  • CHS–BUF, 08/28/26 – 09/04/26: From $273
    28

    Fr

  • CHS–BUF, 08/29/26 – 09/05/26: From $262
    29

    Sa

  • CHS–BUF, 08/30/26 – 09/06/26: From $288
    30

    Su

  • CHS–BUF, 08/31/26 – 09/07/26: From $281
    31

    Mo

  • CHS–BUF, 09/01/26 – 09/08/26: From $197
    01

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    SEP

  • CHS–BUF, 09/02/26 – 09/09/26: From $197
    02

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  • CHS–BUF, 09/03/26 – 09/10/26: From $272
    03

    Th

  • CHS–BUF, 09/04/26 – 09/11/26: From $338
    04

    Fr

  • CHS–BUF, 09/05/26 – 09/12/26: From $197
    05

    Sa

  • CHS–BUF, 09/06/26 – 09/13/26: From $255
    06

    Su

  • CHS–BUF, 09/07/26 – 09/14/26: From $530
    07

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  • CHS–BUF: cmp-view-offers-disclaimer. Find Offers
    08

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  • CHS–BUF: cmp-view-offers-disclaimer. Find Offers
    09

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  • CHS–BUF: cmp-view-offers-disclaimer. Find Offers
    10

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  • CHS–BUF, 09/11/26 – 09/18/26: From $219
    11

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    • range$197-$652

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Charleston, SC to Buffalo flights

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    Charleston, SC (CHS)to

    Buffalo (BUF)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    Charleston, SC (CHS)to

    Buffalo (BUF)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    Charleston, SC (CHS)to

    Buffalo (BUF)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    Charleston, SC (CHS)to

    Buffalo (BUF)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    Charleston, SC (CHS)to

    Buffalo (BUF)
    10/03/26 - 10/10/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    Charleston, SC (CHS)to

    Buffalo (BUF)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    Charleston, SC (CHS)to

    Buffalo (BUF)
    09/21/26 - 09/28/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    Charleston, SC (CHS)to

    Buffalo (BUF)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 10 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Charleston, SC to Buffalo

    Looking for lower fares on your trip from Charleston, SC to Buffalo? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Charleston, SC to Buffalo