American Airlines flights from Jacksonville to Buffalo

Recent searches for flights from Jacksonville to Buffalo

Sep 2026
From$373*
Updated: 3 hours ago
Round tripIEconomy
Oct 2026
From$197*
Updated: 3 hours ago
Round tripIEconomy
Nov 2026
From$197*
Updated: 3 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $197
cmp-daily-histogram-bars-legend-max-price-aria-label $797
Displaying fares for September-2026
  • JAX–BUF: cmp-view-offers-disclaimer. Find Offers
    14

    Mo

    SEP

  • JAX–BUF, 09/15/26 – 09/22/26: From $569
    15

    Tu

  • JAX–BUF, 09/16/26 – 09/23/26: From $771
    16

    We

  • JAX–BUF, 09/17/26 – 09/24/26: From $707
    17

    Th

  • JAX–BUF, 09/18/26 – 09/25/26: From $699
    18

    Fr

  • JAX–BUF, 09/19/26 – 09/26/26: From $569
    19

    Sa

  • JAX–BUF, 09/20/26 – 09/27/26: From $699
    20

    Su

  • JAX–BUF, 09/21/26 – 09/28/26: From $797
    21

    Mo

  • JAX–BUF, 09/22/26 – 09/29/26: From $509
    22

    Tu

  • JAX–BUF, 09/23/26 – 09/30/26: From $509
    23

    We

  • JAX–BUF, 09/24/26 – 10/01/26: From $570
    24

    Th

  • JAX–BUF, 09/25/26 – 10/02/26: From $570
    25

    Fr

  • JAX–BUF, 09/26/26 – 10/03/26: From $509
    26

    Sa

  • JAX–BUF, 09/27/26 – 10/04/26: From $570
    27

    Su

  • JAX–BUF, 09/28/26 – 10/05/26: From $424
    28

    Mo

  • JAX–BUF, 09/29/26 – 10/06/26: From $373
    29

    Tu

  • JAX–BUF, 09/30/26 – 10/07/26: From $373
    30

    We

  • JAX–BUF, 10/01/26 – 10/08/26: From $554
    01

    Th

    OCT

  • JAX–BUF, 10/02/26 – 10/09/26: From $463
    02

    Fr

  • JAX–BUF, 10/03/26 – 10/10/26: From $373
    03

    Sa

  • JAX–BUF, 10/04/26 – 10/11/26: From $463
    04

    Su

  • JAX–BUF, 10/05/26 – 10/12/26: From $311
    05

    Mo

  • JAX–BUF, 10/06/26 – 10/13/26: From $197
    06

    Tu

  • JAX–BUF, 10/07/26 – 10/14/26: From $296
    07

    We

  • JAX–BUF, 10/08/26 – 10/15/26: From $399
    08

    Th

  • JAX–BUF, 10/09/26 – 10/16/26: From $539
    09

    Fr

  • JAX–BUF, 10/10/26 – 10/17/26: From $197
    10

    Sa

  • JAX–BUF, 10/11/26 – 10/18/26: From $477
    11

    Su

  • JAX–BUF: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • JAX–BUF: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

    • range$197-$797

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Jacksonville to Buffalo flights

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    keyboard_arrow_down

    Jacksonville (JAX)to

    Buffalo (BUF)
    10/10/26 - 10/17/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Buffalo (BUF)
    10/21/26 - 10/28/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Buffalo (BUF)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Buffalo (BUF)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Buffalo (BUF)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Buffalo (BUF)
    11/07/26 - 11/14/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Buffalo (BUF)
    10/06/26 - 10/13/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    Jacksonville (JAX)to

    Buffalo (BUF)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $197Fare subject to changes
    Updated: 3 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Jacksonville to Buffalo

    Looking for lower fares on your trip from Jacksonville to Buffalo? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Jacksonville to Buffalo