American Airlines flights from San Diego to Buffalo

Recent searches for flights from San Diego to Buffalo

Sep 2026
From$450*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$327*
Updated: 5 hours ago
Round tripIEconomy
Nov 2026
From$327*
Updated: 5 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $327
cmp-daily-histogram-bars-legend-max-price-aria-label $1.1K
Displaying fares for September-2026
  • SAN–BUF: cmp-view-offers-disclaimer. Find Offers
    12

    Sa

    SEP

  • SAN–BUF, 09/13/26 – 09/20/26: From $1,066
    13

    Su

  • SAN–BUF, 09/14/26 – 09/21/26: From $957
    14

    Mo

  • SAN–BUF, 09/15/26 – 09/22/26: From $893
    15

    Tu

  • SAN–BUF, 09/16/26 – 09/23/26: From $967
    16

    We

  • SAN–BUF, 09/17/26 – 09/24/26: From $1,012
    17

    Th

  • SAN–BUF, 09/18/26 – 09/25/26: From $937
    18

    Fr

  • SAN–BUF, 09/19/26 – 09/26/26: From $724
    19

    Sa

  • SAN–BUF, 09/20/26 – 09/27/26: From $912
    20

    Su

  • SAN–BUF, 09/21/26 – 09/28/26: From $887
    21

    Mo

  • SAN–BUF, 09/22/26 – 09/30/26: From $704
    22

    Tu

  • SAN–BUF, 09/23/26 – 09/30/26: From $724
    23

    We

  • SAN–BUF, 09/24/26 – 10/01/26: From $786
    24

    Th

  • SAN–BUF, 09/25/26 – 10/02/26: From $786
    25

    Fr

  • SAN–BUF, 09/26/26 – 10/03/26: From $450
    26

    Sa

  • SAN–BUF, 09/27/26 – 10/04/26: From $626
    27

    Su

  • SAN–BUF, 09/28/26 – 10/05/26: From $570
    28

    Mo

  • SAN–BUF, 09/29/26 – 10/06/26: From $450
    29

    Tu

  • SAN–BUF, 09/30/26 – 10/07/26: From $450
    30

    We

  • SAN–BUF, 10/01/26 – 10/08/26: From $536
    01

    Th

    OCT

  • SAN–BUF, 10/02/26 – 10/09/26: From $626
    02

    Fr

  • SAN–BUF, 10/03/26 – 10/10/26: From $363
    03

    Sa

  • SAN–BUF, 10/04/26 – 10/11/26: From $503
    04

    Su

  • SAN–BUF, 10/05/26 – 10/12/26: From $503
    05

    Mo

  • SAN–BUF, 10/06/26 – 10/13/26: From $327
    06

    Tu

  • SAN–BUF, 10/07/26 – 10/14/26: From $327
    07

    We

  • SAN–BUF, 10/08/26 – 10/15/26: From $443
    08

    Th

  • SAN–BUF, 10/09/26 – 10/16/26: From $327
    09

    Fr

  • SAN–BUF: cmp-view-offers-disclaimer. Find Offers
    10

    Sa

  • SAN–BUF: cmp-view-offers-disclaimer. Find Offers
    11

    Su

    • range$327-$1,066

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on San Diego to Buffalo flights

    $
    keyboard_arrow_down

    San Diego (SAN)to

    Buffalo (BUF)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    San Diego (SAN)to

    Buffalo (BUF)
    10/16/26 - 10/23/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    San Diego (SAN)to

    Buffalo (BUF)
    10/22/26 - 10/29/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    San Diego (SAN)to

    Buffalo (BUF)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    San Diego (SAN)to

    Buffalo (BUF)
    12/03/26 - 12/10/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    San Diego (SAN)to

    Buffalo (BUF)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    San Diego (SAN)to

    Buffalo (BUF)
    12/06/26 - 12/13/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    San Diego (SAN)to

    Buffalo (BUF)
    11/03/26 - 11/10/26

    Round trip

    Economy

    from
    $327Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from San Diego to Buffalo

    Looking for lower fares on your trip from San Diego to Buffalo? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from San Diego to Buffalo