American Airlines flights from Des Moines to Myrtle Beach

Recent searches for flights from Des Moines to Myrtle Beach

Sep 2026
From$404*
Updated: 2 hours ago
Round tripIEconomy
Oct 2026
From$291*
Updated: 2 hours ago
Round tripIEconomy
Nov 2026
From$291*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $352
cmp-daily-histogram-bars-legend-max-price-aria-label $912
Displaying fares for September-2026
  • DSM–MYR, 09/17/26 – 09/24/26: From $912
    17

    Th

    SEP

  • DSM–MYR, 09/18/26 – 09/25/26: From $912
    18

    Fr

  • DSM–MYR, 09/19/26 – 09/26/26: From $847
    19

    Sa

  • DSM–MYR, 09/20/26 – 09/27/26: From $912
    20

    Su

  • DSM–MYR, 09/21/26 – 09/28/26: From $912
    21

    Mo

  • DSM–MYR, 09/22/26 – 09/26/26: From $849
    22

    Tu

  • DSM–MYR, 09/23/26 – 09/30/26: From $688
    23

    We

  • DSM–MYR, 09/24/26 – 10/01/26: From $688
    24

    Th

  • DSM–MYR, 09/25/26 – 10/02/26: From $688
    25

    Fr

  • DSM–MYR, 09/26/26 – 10/03/26: From $688
    26

    Sa

  • DSM–MYR, 09/27/26 – 10/04/26: From $807
    27

    Su

  • DSM–MYR, 09/28/26 – 10/05/26: From $607
    28

    Mo

  • DSM–MYR, 09/29/26 – 10/06/26: From $588
    29

    Tu

  • DSM–MYR, 09/30/26 – 10/07/26: From $404
    30

    We

  • DSM–MYR, 10/01/26 – 10/08/26: From $607
    01

    Th

    OCT

  • DSM–MYR, 10/02/26 – 10/09/26: From $439
    02

    Fr

  • DSM–MYR, 10/03/26 – 10/10/26: From $404
    03

    Sa

  • DSM–MYR, 10/04/26 – 10/11/26: From $749
    04

    Su

  • DSM–MYR, 10/05/26 – 10/12/26: From $387
    05

    Mo

  • DSM–MYR, 10/06/26 – 10/13/26: From $352
    06

    Tu

  • DSM–MYR, 10/07/26 – 10/14/26: From $395
    07

    We

  • DSM–MYR, 10/08/26 – 10/15/26: From $763
    08

    Th

  • DSM–MYR, 10/09/26 – 10/16/26: From $650
    09

    Fr

  • DSM–MYR, 10/10/26 – 10/17/26: From $357
    10

    Sa

  • DSM–MYR, 10/11/26 – 10/18/26: From $672
    11

    Su

  • DSM–MYR, 10/12/26 – 10/19/26: From $587
    12

    Mo

  • DSM–MYR, 10/13/26 – 10/20/26: From $387
    13

    Tu

  • DSM–MYR: cmp-view-offers-disclaimer. Find Offers
    14

    We

  • DSM–MYR: cmp-view-offers-disclaimer. Find Offers
    15

    Th

  • DSM–MYR: cmp-view-offers-disclaimer. Find Offers
    16

    Fr

    • range$352-$912

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Des Moines to Myrtle Beach flights

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    Des Moines (DSM)to

    Myrtle Beach (MYR)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    Des Moines (DSM)to

    Myrtle Beach (MYR)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    Des Moines (DSM)to

    Myrtle Beach (MYR)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    Des Moines (DSM)to

    Myrtle Beach (MYR)
    12/05/26 - 12/12/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    Des Moines (DSM)to

    Myrtle Beach (MYR)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    Des Moines (DSM)to

    Myrtle Beach (MYR)
    11/18/26 - 11/25/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    Des Moines (DSM)to

    Myrtle Beach (MYR)
    10/17/26 - 10/24/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    Des Moines (DSM)to

    Myrtle Beach (MYR)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $291Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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