American Airlines flights from Louisville to Myrtle Beach

Recent searches for flights from Louisville to Myrtle Beach

Sep 2026
From$374*
Updated: 5 hours ago
Round tripIEconomy
Oct 2026
From$279*
Updated: 5 hours ago
Round tripIEconomy
Nov 2026
From$279*
Updated: 5 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $279
cmp-daily-histogram-bars-legend-max-price-aria-label $672
Displaying fares for September-2026
  • SDF–MYR: cmp-view-offers-disclaimer. Find Offers
    10

    Th

    SEP

  • SDF–MYR, 09/11/26 – 09/18/26: From $672
    11

    Fr

  • SDF–MYR, 09/12/26 – 09/19/26: From $535
    12

    Sa

  • SDF–MYR, 09/13/26 – 09/20/26: From $672
    13

    Su

  • SDF–MYR, 09/14/26 – 09/22/26: From $651
    14

    Mo

  • SDF–MYR, 09/15/26 – 09/22/26: From $535
    15

    Tu

  • SDF–MYR, 09/16/26 – 09/20/26: From $626
    16

    We

  • SDF–MYR, 09/17/26 – 09/24/26: From $593
    17

    Th

  • SDF–MYR, 09/18/26 – 09/25/26: From $593
    18

    Fr

  • SDF–MYR, 09/19/26 – 09/26/26: From $502
    19

    Sa

  • SDF–MYR, 09/20/26 – 09/27/26: From $593
    20

    Su

  • SDF–MYR, 09/21/26 – 09/28/26: From $664
    21

    Mo

  • SDF–MYR, 09/22/26 – 09/29/26: From $502
    22

    Tu

  • SDF–MYR, 09/23/26 – 09/30/26: From $502
    23

    We

  • SDF–MYR, 09/24/26 – 10/01/26: From $432
    24

    Th

  • SDF–MYR, 09/25/26 – 10/02/26: From $452
    25

    Fr

  • SDF–MYR, 09/26/26 – 10/03/26: From $374
    26

    Sa

  • SDF–MYR, 09/27/26 – 10/04/26: From $651
    27

    Su

  • SDF–MYR, 09/28/26 – 10/05/26: From $623
    28

    Mo

  • SDF–MYR, 09/29/26 – 10/06/26: From $374
    29

    Tu

  • SDF–MYR, 09/30/26 – 10/07/26: From $374
    30

    We

  • SDF–MYR, 10/01/26 – 10/08/26: From $462
    01

    Th

    OCT

  • SDF–MYR, 10/02/26 – 10/09/26: From $404
    02

    Fr

  • SDF–MYR, 10/03/26 – 10/10/26: From $395
    03

    Sa

  • SDF–MYR, 10/04/26 – 10/11/26: From $550
    04

    Su

  • SDF–MYR, 10/05/26 – 10/12/26: From $309
    05

    Mo

  • SDF–MYR, 10/06/26 – 10/13/26: From $279
    06

    Tu

  • SDF–MYR, 10/07/26 – 10/14/26: From $279
    07

    We

  • SDF–MYR: cmp-view-offers-disclaimer. Find Offers
    08

    Th

  • SDF–MYR: cmp-view-offers-disclaimer. Find Offers
    09

    Fr

    • range$279-$672

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Louisville to Myrtle Beach flights

    $
    keyboard_arrow_down

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/19/26 - 10/26/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/13/26 - 10/20/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 5 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Louisville to Myrtle Beach

    Looking for lower fares on your trip from Louisville to Myrtle Beach? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Louisville to Myrtle Beach