American Airlines flights from Louisville to Myrtle Beach

Recent searches for flights from Louisville to Myrtle Beach

Aug 2026
From$502*
Updated: 2 hours ago
Round tripIEconomy
Sep 2026
From$279*
Updated: 2 hours ago
Round tripIEconomy
Oct 2026
From$279*
Updated: 2 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $279
cmp-daily-histogram-bars-legend-max-price-aria-label $743
Displaying fares for August-2026
  • SDF–MYR, 08/21/26 – 08/28/26: From $672
    21

    Fr

    AUG

  • SDF–MYR, 08/22/26 – 08/29/26: From $535
    22

    Sa

  • SDF–MYR, 08/23/26 – 08/30/26: From $672
    23

    Su

  • SDF–MYR, 08/24/26 – 08/31/26: From $672
    24

    Mo

  • SDF–MYR, 08/25/26 – 09/01/26: From $535
    25

    Tu

  • SDF–MYR, 08/26/26 – 09/02/26: From $535
    26

    We

  • SDF–MYR, 08/27/26 – 09/03/26: From $697
    27

    Th

  • SDF–MYR, 08/28/26 – 09/04/26: From $593
    28

    Fr

  • SDF–MYR, 08/29/26 – 09/05/26: From $502
    29

    Sa

  • SDF–MYR, 08/30/26 – 09/06/26: From $593
    30

    Su

  • SDF–MYR, 08/31/26 – 09/07/26: From $743
    31

    Mo

  • SDF–MYR, 09/01/26 – 09/08/26: From $610
    01

    Tu

    SEP

  • SDF–MYR, 09/02/26 – 09/09/26: From $502
    02

    We

  • SDF–MYR, 09/03/26 – 09/10/26: From $593
    03

    Th

  • SDF–MYR, 09/04/26 – 09/11/26: From $633
    04

    Fr

  • SDF–MYR, 09/05/26 – 09/12/26: From $330
    05

    Sa

  • SDF–MYR, 09/06/26 – 09/13/26: From $389
    06

    Su

  • SDF–MYR, 09/07/26 – 09/14/26: From $374
    07

    Mo

  • SDF–MYR, 09/08/26 – 09/15/26: From $374
    08

    Tu

  • SDF–MYR, 09/09/26 – 09/13/26: From $389
    09

    We

  • SDF–MYR, 09/10/26 – 09/17/26: From $330
    10

    Th

  • SDF–MYR, 09/11/26 – 09/18/26: From $299
    11

    Fr

  • SDF–MYR, 09/12/26 – 09/19/26: From $314
    12

    Sa

  • SDF–MYR, 09/13/26 – 09/20/26: From $428
    13

    Su

  • SDF–MYR, 09/14/26 – 09/21/26: From $279
    14

    Mo

  • SDF–MYR, 09/15/26 – 09/22/26: From $279
    15

    Tu

  • SDF–MYR, 09/16/26 – 09/23/26: From $349
    16

    We

  • SDF–MYR, 09/17/26 – 09/24/26: From $369
    17

    Th

  • SDF–MYR: cmp-view-offers-disclaimer. Find Offers
    18

    Fr

  • SDF–MYR: cmp-view-offers-disclaimer. Find Offers
    19

    Sa

  • SDF–MYR, 09/20/26 – 09/27/26: From $357
    20

    Su

    • range$279-$743

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Louisville to Myrtle Beach flights

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    keyboard_arrow_down

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/14/26 - 10/21/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/24/26 - 10/31/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/29/26 - 11/05/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    10/31/26 - 11/07/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    09/23/26 - 09/30/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    Louisville (SDF)to

    Myrtle Beach (MYR)
    11/04/26 - 11/11/26

    Round trip

    Economy

    from
    $279Fare subject to changes
    Updated: 2 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Louisville to Myrtle Beach

    Looking for lower fares on your trip from Louisville to Myrtle Beach? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Louisville to Myrtle Beach