American Airlines flights from Detroit to Key West

Recent searches for flights from Detroit to Key West

Sep 2026
From$459*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$353*
Updated: 4 hours ago
Round tripIEconomy
Nov 2026
From$353*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $406
cmp-daily-histogram-bars-legend-max-price-aria-label $759
Displaying fares for September-2026
  • DTW–EYW, 09/16/26 – 09/23/26: From $459
    16

    We

    SEP

  • DTW–EYW, 09/17/26 – 09/28/26: From $709
    17

    Th

  • DTW–EYW, 09/18/26 – 09/25/26: From $730
    18

    Fr

  • DTW–EYW, 09/19/26 – 09/26/26: From $523
    19

    Sa

  • DTW–EYW, 09/20/26 – 09/27/26: From $759
    20

    Su

  • DTW–EYW, 09/21/26 – 09/28/26: From $735
    21

    Mo

  • DTW–EYW, 09/22/26 – 09/29/26: From $492
    22

    Tu

  • DTW–EYW, 09/23/26 – 09/30/26: From $459
    23

    We

  • DTW–EYW, 09/24/26 – 10/06/26: From $621
    24

    Th

  • DTW–EYW, 09/25/26 – 10/02/26: From $693
    25

    Fr

  • DTW–EYW, 09/26/26 – 10/03/26: From $459
    26

    Sa

  • DTW–EYW, 09/27/26 – 10/04/26: From $613
    27

    Su

  • DTW–EYW, 09/28/26 – 10/05/26: From $613
    28

    Mo

  • DTW–EYW, 09/29/26 – 10/06/26: From $459
    29

    Tu

  • DTW–EYW, 09/30/26 – 10/07/26: From $459
    30

    We

  • DTW–EYW, 10/01/26 – 10/08/26: From $678
    01

    Th

    OCT

  • DTW–EYW, 10/02/26 – 10/09/26: From $641
    02

    Fr

  • DTW–EYW, 10/03/26 – 10/10/26: From $523
    03

    Sa

  • DTW–EYW, 10/04/26 – 10/11/26: From $730
    04

    Su

  • DTW–EYW, 10/05/26 – 10/12/26: From $759
    05

    Mo

  • DTW–EYW, 10/06/26 – 10/13/26: From $523
    06

    Tu

  • DTW–EYW, 10/07/26 – 10/14/26: From $459
    07

    We

  • DTW–EYW, 10/08/26 – 10/15/26: From $641
    08

    Th

  • DTW–EYW, 10/09/26 – 10/16/26: From $633
    09

    Fr

  • DTW–EYW, 10/10/26 – 10/17/26: From $512
    10

    Sa

  • DTW–EYW, 10/11/26 – 10/18/26: From $556
    11

    Su

  • DTW–EYW, 10/12/26 – 10/19/26: From $491
    12

    Mo

  • DTW–EYW, 10/13/26 – 10/20/26: From $406
    13

    Tu

  • DTW–EYW, 10/14/26 – 10/20/26: From $406
    14

    We

  • DTW–EYW: cmp-view-offers-disclaimer. Find Offers
    15

    Th

    • range$406-$759

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Detroit to Key West flights

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    Detroit (DTW)to

    Key West (EYW)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    Detroit (DTW)to

    Key West (EYW)
    12/02/26 - 12/09/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    Detroit (DTW)to

    Key West (EYW)
    11/24/26 - 12/01/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    Detroit (DTW)to

    Key West (EYW)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    Detroit (DTW)to

    Key West (EYW)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    Detroit (DTW)to

    Key West (EYW)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    Detroit (DTW)to

    Key West (EYW)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    Detroit (DTW)to

    Key West (EYW)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

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