American Airlines flights from Louisville to Key West

Recent searches for flights from Louisville to Key West

Aug 2026
From$338*
Updated: 4 hours ago
Round tripIEconomy
Sep 2026
From$333*
Updated: 4 hours ago
Round tripIEconomy
Oct 2026
From$333*
Updated: 4 hours ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $338
cmp-daily-histogram-bars-legend-max-price-aria-label $730
Displaying fares for August-2026
  • SDF–EYW: cmp-view-offers-disclaimer. Find Offers
    04

    Tu

    AUG

  • SDF–EYW, 08/05/26 – 08/12/26: From $439
    05

    We

  • SDF–EYW, 08/06/26 – 08/13/26: From $633
    06

    Th

  • SDF–EYW, 08/07/26 – 08/14/26: From $499
    07

    Fr

  • SDF–EYW, 08/08/26 – 08/15/26: From $589
    08

    Sa

  • SDF–EYW, 08/09/26 – 08/16/26: From $730
    09

    Su

  • SDF–EYW, 08/10/26 – 08/17/26: From $658
    10

    Mo

  • SDF–EYW, 08/11/26 – 08/18/26: From $464
    11

    Tu

  • SDF–EYW, 08/12/26 – 08/19/26: From $417
    12

    We

  • SDF–EYW, 08/13/26 – 08/20/26: From $534
    13

    Th

  • SDF–EYW, 08/14/26 – 08/21/26: From $442
    14

    Fr

  • SDF–EYW, 08/15/26 – 08/22/26: From $417
    15

    Sa

  • SDF–EYW, 08/16/26 – 08/23/26: From $581
    16

    Su

  • SDF–EYW, 08/17/26 – 08/24/26: From $611
    17

    Mo

  • SDF–EYW, 08/18/26 – 08/25/26: From $369
    18

    Tu

  • SDF–EYW, 08/19/26 – 08/26/26: From $369
    19

    We

  • SDF–EYW, 08/20/26 – 08/27/26: From $582
    20

    Th

  • SDF–EYW, 08/21/26 – 08/28/26: From $369
    21

    Fr

  • SDF–EYW, 08/22/26 – 08/29/26: From $369
    22

    Sa

  • SDF–EYW, 08/23/26 – 08/30/26: From $534
    23

    Su

  • SDF–EYW, 08/24/26 – 08/31/26: From $411
    24

    Mo

  • SDF–EYW, 08/25/26 – 09/01/26: From $343
    25

    Tu

  • SDF–EYW, 08/26/26 – 09/02/26: From $338
    26

    We

  • SDF–EYW, 08/27/26 – 09/03/26: From $508
    27

    Th

  • SDF–EYW, 08/28/26 – 09/04/26: From $343
    28

    Fr

  • SDF–EYW, 08/29/26 – 09/05/26: From $338
    29

    Sa

  • SDF–EYW, 08/30/26 – 09/06/26: From $565
    30

    Su

  • SDF–EYW, 08/31/26 – 09/07/26: From $717
    31

    Mo

  • SDF–EYW: cmp-view-offers-disclaimer. Find Offers
    01

    Tu

    SEP

  • SDF–EYW: cmp-view-offers-disclaimer. Find Offers
    02

    We

  • SDF–EYW: cmp-view-offers-disclaimer. Find Offers
    03

    Th

    • range$338-$730

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Louisville to Key West flights

    $
    keyboard_arrow_down

    Louisville (SDF)to

    Key West (EYW)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    Louisville (SDF)to

    Key West (EYW)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    Louisville (SDF)to

    Key West (EYW)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    Louisville (SDF)to

    Key West (EYW)
    09/12/26 - 09/19/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    Louisville (SDF)to

    Key West (EYW)
    09/16/26 - 09/23/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    Louisville (SDF)to

    Key West (EYW)
    09/22/26 - 09/29/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    Louisville (SDF)to

    Key West (EYW)
    09/29/26 - 10/06/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    Louisville (SDF)to

    Key West (EYW)
    09/30/26 - 10/07/26

    Round trip

    Economy

    from
    $333Fare subject to changes
    Updated: 4 hours ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Louisville to Key West

    Looking for lower fares on your trip from Louisville to Key West? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

    Earn up to $500 back on your next American Airlines flight plus, 30,000 bonus miles. Offers vary elsewhere. Opens another site in a new window that may not meet accessibility guidelines.

    Upgrade your flight with Main Cabin Extra

    Make your trip more comfortable with Main Cabin Extra. Enjoy benefits like:

    • Extra legroom: More space with seats at the front of the Main Cabin or in exit rows.
    • Early boarding: Preferred Group 5 boarding allows easier access to overhead bins.
    • Complimentary drinks: Enjoy beer, wine and spirits on flights with full beverage service.

    Discover how Main Cabin Extra can enhance your trip.

    American Airlines flights from Louisville to Key West