American Airlines flights from Louisville to Key West

Recent searches for flights from Louisville to Key West

Sep 2026
From$389*
Updated: 1 hour ago
Round tripIEconomy
Oct 2026
From$353*
Updated: 1 hour ago
Round tripIEconomy
Nov 2026
From$353*
Updated: 1 hour ago
Round tripIEconomy
cmp-daily-histogram-bars-legend-min-price-aria-label $389
cmp-daily-histogram-bars-legend-max-price-aria-label $750
Displaying fares for September-2026
  • SDF–EYW, 09/14/26 – 09/21/26: From $519
    14

    Mo

    SEP

  • SDF–EYW, 09/15/26 – 09/22/26: From $459
    15

    Tu

  • SDF–EYW, 09/16/26 – 09/23/26: From $563
    16

    We

  • SDF–EYW, 09/17/26 – 09/24/26: From $519
    17

    Th

  • SDF–EYW, 09/18/26 – 09/25/26: From $519
    18

    Fr

  • SDF–EYW, 09/19/26 – 09/26/26: From $568
    19

    Sa

  • SDF–EYW, 09/20/26 – 09/27/26: From $750
    20

    Su

  • SDF–EYW, 09/21/26 – 09/28/26: From $509
    21

    Mo

  • SDF–EYW, 09/22/26 – 09/29/26: From $437
    22

    Tu

  • SDF–EYW, 09/23/26 – 09/30/26: From $437
    23

    We

  • SDF–EYW, 09/24/26 – 10/01/26: From $631
    24

    Th

  • SDF–EYW, 09/25/26 – 10/02/26: From $462
    25

    Fr

  • SDF–EYW, 09/26/26 – 10/03/26: From $563
    26

    Sa

  • SDF–EYW, 09/27/26 – 10/04/26: From $690
    27

    Su

  • SDF–EYW, 09/28/26 – 10/05/26: From $667
    28

    Mo

  • SDF–EYW, 09/29/26 – 10/06/26: From $389
    29

    Tu

  • SDF–EYW, 09/30/26 – 10/07/26: From $389
    30

    We

  • SDF–EYW, 10/01/26 – 10/08/26: From $673
    01

    Th

    OCT

  • SDF–EYW, 10/02/26 – 10/09/26: From $596
    02

    Fr

  • SDF–EYW, 10/03/26 – 10/10/26: From $588
    03

    Sa

  • SDF–EYW, 10/04/26 – 10/11/26: From $707
    04

    Su

  • SDF–EYW, 10/05/26 – 10/12/26: From $605
    05

    Mo

  • SDF–EYW, 10/06/26 – 10/13/26: From $563
    06

    Tu

  • SDF–EYW, 10/07/26 – 10/14/26: From $510
    07

    We

  • SDF–EYW, 10/08/26 – 10/15/26: From $610
    08

    Th

  • SDF–EYW, 10/09/26 – 10/16/26: From $568
    09

    Fr

  • SDF–EYW, 10/10/26 – 10/17/26: From $492
    10

    Sa

  • SDF–EYW, 10/11/26 – 10/18/26: From $613
    11

    Su

  • SDF–EYW: cmp-view-offers-disclaimer. Find Offers
    12

    Mo

  • SDF–EYW: cmp-view-offers-disclaimer. Find Offers
    13

    Tu

    • range$389-$750

    DisclaimerFares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Fares listed may be Basic Economy, which class is subject to additional terms and conditions. Additional baggage fees and charges for optional products and services may apply.

    Find deals on Louisville to Key West flights

    $
    keyboard_arrow_down

    Louisville (SDF)to

    Key West (EYW)
    10/20/26 - 10/27/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    Louisville (SDF)to

    Key West (EYW)
    10/27/26 - 11/03/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    Louisville (SDF)to

    Key West (EYW)
    10/28/26 - 11/04/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    Louisville (SDF)to

    Key West (EYW)
    12/09/26 - 12/16/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    Louisville (SDF)to

    Key West (EYW)
    12/08/26 - 12/15/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    Louisville (SDF)to

    Key West (EYW)
    11/10/26 - 11/17/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    Louisville (SDF)to

    Key West (EYW)
    11/17/26 - 11/24/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    Louisville (SDF)to

    Key West (EYW)
    11/24/26 - 12/01/26

    Round trip

    Economy

    from
    $353Fare subject to changes
    Updated: 1 hour ago

    *Fares displayed have been collected within the last 24hrs and may no longer be available at time of booking. Some fares listed may include one or more connections that are Basic Economy, which class is subject to additional terms and conditions. Modifying this information may result in a different fare. To find the most updated fare, please visit aa.com. Additional baggage fees and charges for optional products and services may apply.

    Finding cheap flights from Louisville to Key West

    Looking for lower fares on your trip from Louisville to Key West? Here are a few ways to save.

    • Book early: Booking 1 to 3 months ahead can help you find lower fares
    • Be flexible with dates: Midweek travel, like Tuesdays and Wednesdays, can be more affordable
    • Travel during less busy periods: Flying outside peak travel times can help find lower fares and avoid crowds

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    American Airlines flights from Louisville to Key West